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Manager Principal Scientist Jobs (NOW HIRING)

Arclin

Principal Scientist

Macon, GA · On-site

Principal Scientist - Rubber & Tire Technologies Location: Macon, GA Department: Research ... Strong project management skills and ability to manage multiple priorities. * History of mentoring ...

Exponent

Principal Scientist

Seattle, WA · On-site

$225K - $275K/yr

Principal Scientist ID: 2025-2214 Location: US-CA-Menlo Park Practice: Polymers and Chemistry ... Building, managing, and empowering multidisciplinary teams, fostering a collaborative and inclusive ...

Exponent

Principal Scientist

Menlo Park, CA · On-site

$225K - $275K/yr

Principal Scientist ID: 2025-2214 Location: US-CA-Menlo Park Practice: Polymers and Chemistry ... Building, managing, and empowering multidisciplinary teams, fostering a collaborative and inclusive ...

Arclin

Principal Scientist

Macon, GA · On-site

Principal Scientist - Rubber & Tire Technologies Location: Macon, GA Department: Research ... Strong project management skills and ability to manage multiple priorities. * History of mentoring ...

Arclin

Principal Scientist

Macon, GA · On-site

Principal Scientist - Rubber & Tire Technologies Location: Macon, GA Department: Research ... Strong project management skills and ability to manage multiple priorities. * History of mentoring ...

Actalent

Principal Scientist

Bartlett, IL · On-site

$100K - $150K/yr

Principal Scientist As a Principal Scientist, you will lead advanced enzyme research and product ... Manage external relationships with food research institutes. * Optimize operational performance and ...

Arclin USA LLC

Principal Scientist

Macon, GA · On-site

Principal Scientist - Rubber & Tire Technologies Location: Macon, GA Department: Research ... Strong project management skills and ability to manage multiple priorities. * History of mentoring ...

Focus Laboratories

Principal Scientist

Cherry Hill, NJ · On-site

$118K - $135K/yr

What You'll Lead TPM Laboratories is hiring a Principal Scientist to serve as the lab's top ... management strategy. - Direct complex studies (including forced degradation) and resolve high ...

Focus Lab

Principal Scientist

Cherry Hill, NJ · On-site

What You'll Lead TPM Laboratories is hiring a Principal Scientist to serve as the lab's top ... Lead method development, validation, transfer, and lifecycle management strategy. * Direct complex ...

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Manager Principal Scientist information

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$68.5K

$144K

$190.5K

How much do manager principal scientist jobs pay per year?

As of Sep 14, 2026, the average yearly pay for manager principal scientist in the United States is $144,009.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,500.00 and $169,000.00 per year, depending on experience, location, and employer.

What is a manager principal scientist?

Manager Principal Scientists are experienced researchers who lead scientific teams and projects, often within industries like pharmaceuticals, biotechnology, or environmental science. They combine deep scientific expertise with leadership responsibilities, overseeing research activities, mentoring staff, and ensuring project goals align with organizational strategy. In addition to conducting high-level research, they manage budgets, collaborate across departments, and contribute to setting the scientific direction of their organization.

What are the key skills and qualifications needed to thrive as a manager principal scientist?

To thrive as a Manager Principal Scientist, you need advanced scientific expertise, typically a PhD in a relevant field, and substantial experience in research and project leadership. Proficiency with specialized laboratory equipment, data analysis software, and familiarity with regulatory compliance systems are commonly required. Outstanding leadership, mentoring abilities, and cross-functional communication skills help distinguish top performers in this role. These competencies are crucial for driving innovative research, ensuring project success, and effectively leading scientific teams.

How does a manager principal scientist typically balance leadership responsibilities with hands-on scientific research?

A Manager Principal Scientist is often expected to split their time between leading a team and contributing directly to research projects. This means overseeing the scientific direction, mentoring junior scientists, and ensuring project milestones are met, while also designing experiments and analyzing data themselves. Balancing these responsibilities can be challenging, but strong organizational skills and effective delegation are crucial. Collaborating with other departments, such as regulatory, clinical, or product development teams, is also a key part of the role, ensuring scientific objectives align with broader organizational goals.

What is the difference between Manager Principal Scientist vs Principal Scientist?

AspectManager Principal ScientistPrincipal Scientist
CredentialsAdvanced degrees (PhD), leadership experience, often managerial certificationsAdvanced degrees (PhD), deep technical expertise, research-focused
Work EnvironmentLeads teams, manages projects, strategic planningConducts independent research, develops scientific innovations
Employer & Industry UsageCommon in biotech, pharma, and R&D firms with team managementFound in similar industries, focusing on technical expertise

The main difference is that a Manager Principal Scientist combines scientific expertise with team leadership and project management, whereas a Principal Scientist primarily focuses on advanced research and technical contributions without managerial duties.

What cities are hiring for Manager Principal Scientist jobs?

Cities with the most Manager Principal Scientist job openings:

What are the most commonly searched types of Principal Scientist jobs?

The most popular types of Principal Scientist jobs are:

What states have the most Manager Principal Scientist jobs?

States with the most job openings for Manager Principal Scientist jobs include:

What are popular job titles related to Manager Principal Scientist jobs?

For Manager Principal Scientist jobs, the most frequently searched job titles are:

Manager Principal Scientist jobs near you

Principal Scientist (Research Scientist)

Lenexa, KS • On-site

ICON
See more jobs at ICONexternal

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 8 days ago

Job description

Principal Scientist (Research Scientist)- Bioanalytical, LC/MS/MS) - Full time, Salary, Benefits - Lenexa, Kansas (KS)
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
Are you a scientist with expertise in method development? Take the next step in your career by joining ICON where you'll advance groundbreaking clinical therapies by leading global client programs.
We are excited to be seeking a new Principal Scientist (Research Scientist) at ICON in Lenexa, Kansas (KS). The Principal Scientist (Research Scientist) will lead and conduct scientific research aimed at advancing clinical trials and developing innovative therapies. You will manage sponsor programs, shape assay strategies, and provide expertise for new and complex modalities.
We are seeking candidates with strong bioanalytical method development experience and expertise in emerging biological modalities.
What You Will Do:
The Principal Scientist (Research Scientist) is responsible for method development and validation for testing preclinical and clinical specimens using LC/MS/MS analytical methods. In addition, you will oversee transfer robust LC/MS/MS methods for biologics for bioanalytical testing.
Key responsibilities include:
  • Independently direct development and validation of new LC/MS/MS assays using appropriate methods such as (but not limited to) Tomtec, Hamilton, Kingfisher, Integra Assist plus, etc.
  • Ensure robust LC/MS/MS methods are developed for successful method validation of both small molecules, radiolabeled analytes and biologics such as proteins, peptides, ADCs, oligonucleotides, monoclonal antibodies (mAb), etc.
  • Review data presentations for accuracy and clarity prior to sharing with sponsors
  • Provide support to Laboratory Operations staff regarding assay quality, expected results, troubleshooting and data review
  • Provide technical input for ICON Marketing collateral, attend conferences, publish papers in the peer-reviewed literature
  • Drive new business by consulting with sponsors on assay requirements for new projects
  • Collaborate with inter-departmental functions to write and review validation plans, reports and SOP's
  • Lead assay transfers to other ICON lab locations

Your Profile:
Required qualifications and experience:
  • PhD or equivalent degree in a relevant scientific field such as biology, chemistry, pharmacology, or clinical research.
  • MS degrees considered with proven LC/MS/MS method development experience in the pharmaceutical or clinical research industry.
  • Experience with some or all of the following: radiolabeled analytes and biologics such as proteins, peptides, ADCs, oligonucleotides, monoclonal antibodies (mAb), etc.
  • Experience in conducting research within the clinical or pharmaceutical industry, with a proven track record of managing scientific projects.
  • Strong analytical skills and expertise in data interpretation and statistical analysis.
  • Excellent written and verbal communication skills, with the ability to present complex scientific information to both technical and non-technical audiences.
  • Willingness to travel as required (approximately 5%)

#LI-KM3
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply

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