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Manager Commercial Operations Jobs in California

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Manager Commercial Operations information

Is a manager commercial operations a high paying job?

A Manager of Commercial Operations typically earns a salary above the median for managerial roles, with compensation varying by industry, location, and experience. These roles often include bonuses and benefits, reflecting their seniority and responsibility level.

What are the key skills and qualifications needed to thrive as a manager commercial operations, and why are they important?

To thrive as a Manager Commercial Operations, you need strong business acumen, analytical skills, and a background in business administration or a related field, often supported by a bachelor's or master's degree. Proficiency in CRM systems, ERP software, and advanced Excel, as well as familiarity with project management tools, is typically required. Exceptional leadership, negotiation, and communication skills help you manage teams and build effective client relationships. These abilities ensure efficient operations, drive revenue growth, and support strategic business objectives in a competitive market.

How much is a manager commercial operations paid?

A Manager of Commercial Operations typically earns between $70,000 and $130,000 annually, depending on experience, industry, and location. They often oversee sales strategies, contract negotiations, and team management, with additional compensation such as bonuses or profit sharing possible.

What is a manager commercial operations?

A Manager Commercial Operations is responsible for overseeing and optimizing the commercial activities of a business, such as sales, marketing, and customer relationships. They analyze market trends, coordinate with different departments, and implement strategies to increase revenue and efficiency. The role often involves budgeting, forecasting, and ensuring that operational processes align with business objectives. Managers in this field are key to driving business growth and maintaining competitive advantage.

What are some common challenges faced by a manager commercial operations, and how can they be effectively addressed?

A Manager of Commercial Operations often navigates challenges such as aligning cross-departmental objectives, managing fluctuating market demands, and ensuring seamless communication between sales, finance, and supply chain teams. To address these, it's important to foster strong collaboration through regular interdepartmental meetings, utilize data-driven decision-making tools, and implement clear processes for information sharing. Developing strong leadership and problem-solving skills can help anticipate potential bottlenecks and promote efficient operations.

What is the difference between Manager Commercial Operations vs Sales Manager?

AspectManager Commercial OperationsSales Manager
Primary FocusOversees commercial strategies, pricing, and contract negotiationsLeads sales teams to meet revenue targets
Required CredentialsBusiness or related degree, experience in commercial strategySales or marketing background, sales certifications often preferred
Work EnvironmentCross-departmental, strategic planningCustomer-facing, team management
Industry UsageCommon in industries with complex contracts like manufacturing, energyPrevalent in retail, B2B services, and tech sectors

The Manager Commercial Operations focuses on strategic commercial activities, including pricing and contract management, while the Sales Manager concentrates on leading sales teams to achieve revenue goals. Both roles require strong business acumen but differ in their core responsibilities and daily tasks.

What are the most commonly searched types of Commercial Operations jobs in California? The most popular types of Commercial Operations jobs in California are:
What are popular job titles related to Manager Commercial Operations jobs in California? For Manager Commercial Operations jobs in California, the most frequently searched job titles are:
What job categories do people searching Manager Commercial Operations jobs in California look for? The top searched job categories for Manager Commercial Operations jobs in California are:
What cities in California are hiring for Manager Commercial Operations jobs? Cities in California with the most Manager Commercial Operations job openings:
Manager Commercial Operations jobs near you
Infographic showing various Manager Commercial Operations job openings in California as of August 2026, with employment types broken down into 96% Full Time, 2% Temporary, and 2% Contract. Highlights an 84% In-person, 8% Hybrid, and 8% Remote job distribution.

Manager, Commercial Operations

Arrowhead Pharmaceuticals

Pasadena, CA • On-site

Full-time

Re-posted 4 days ago

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Let's do something amazing together! The Manager of Sales Operations will play an important role in the commercial success of Arrowhead's leading investigational cardiometabolic medicine - Redemplo (siRNA targeting APOC3). This product has demonstrated compelling clinical data to date, has been approved by the FDA for Familial Chylomicronemia Syndrome (FCS) and is in late-stage development for the treatment of other grievous conditions, including Severe Hypertriglyceridemia (SHTG). Over time, the role will expand to cover additional indications and products in the Arrowhead portfolio.
In this key position, you will be supporting Sales Operations for our field-based teams. Reporting to the Director of Commercial Operations and working closely with Sales and Marketing leadership, you will play an important role in the execution of commercial strategy. Specifically, you will help translate commercial objectives into plan-of-action and goals for the field-based teams, you will support proper sizing, targeting and incentive compensation. You will also help optimize systems (CRM) and manage logistics including fleet administration and support for the field.
This role is based in Pasadena, California, with an expectation to be in office 5 days a week.
Responsibilities
  • Field Excellence
    • Help set national and regional sales targets in compliance with regulations and in alignment with forecasts. Help align targeting and call planning based on business strategy.
    • Help support the implementation and management of sales compensation plans and incentive programs; adjust as necessary to ensure optimal performance; help automate the targeting and incentive programs.
    • Help manage field alignment, workload calculation, and territory mapping as needed. Adjust as necessary to ensure optimal performance. Collaborate with sales leadership to ensure optimal field resource allocation.
  • Build infrastructure and improve process
    • In collaboration with IT - support management of all data pertaining to sales and marketing to ensure smooth operations and reporting, including targeting, IC, KPIs, and field sizing. Maintain customer master data. Optimize data sources for sales planning across field teams. Collaborate in the ongoing improvement of the CRM.
    • Support Commercial Operations budget tracking and assist with vendor relationships and day-to-day vendor coordination.
    • Manage the field fleet program: coordinate vehicle assignments, track lease schedules and renewals, liaise with fleet vendors, ensure compliance with company fleet policy, and serve as the primary point of contact for field team fleet-related needs.
  • Create insights
    • Support the definition, development, and regular communication of business KPIs and metrics to various stakeholders. Collaborate with commercial leadership and business analytics in tracking and reporting on KPIs.

Requirements
  • Bachelor's degree in a business-rated or life sciences field. Strong understanding of the life sciences industry.
  • 5+ years of progressive commercial experience in biotechnology or pharmaceuticals
  • 2+ years of experience in pharmaceutical data/sales operations; including roles such as brand management, data management, sales operations, analytics, forecasting.
  • Strong leadership and communication skills; effective vendor management
  • Ability to work collaboratively in a matrixed, team-based environment, with strong organizational and time management capabilities.
  • You may be required to travel for up to 20% of your time.

Preferred
  • Experience in the cardiometabolic disease space

California pay range
$120,000-$145,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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