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Lnp Formulation Jobs (NOW HIRING)

Crispr Therapeutics

Scientist II, LNP

South Boston, MA · On-site

$130K - $140K/yr

The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different ...

Sail Biomedicines

Sr. Engineer, Drug Product

Cambridge, MA · On-site +1

$130K - $150K/yr

Support process optimization and characterization activities for LNP formulation, TFF, mAb sterile filtration, and final fill. * Support definition and refinement of CPPs, KPPs, CMAs, IPCs, IPTs, and ...

Sail Biomedicines

Sr. Engineer, Drug Product

Cambridge, MA · On-site

$130K - $150K/yr

Support process optimization and characterization activities for LNP formulation, TFF, mAb sterile filtration, and final fill. * Support definition and refinement of CPPs, KPPs, CMAs, IPCs, IPTs, and ...

Crispr Therapeutics

Director, LNP Discovery

Boston, MA

$195K - $215K/yr

Oversee the development of novel LNPs (e.g., lipid chemistry, composition, formulation process) * Oversee the development of cellbased assays and animal models for LNP testing. * Lead LNP Delivery ...

ElevateBio

Scientist, Process Development

Waltham, MA · On-site

Experience with mRNA-LNP formulation and mixing technologies/equipment * Ability to use statistical software such as JMP for Design of Experiments (DoE) and data analysis. * Familiarity with GMP ...

ElevateBio

Scientist, Process Development

Waltham, MA · On-site

Experience with mRNA-LNP formulation and mixing technologies/equipment * Ability to use statistical software such as JMP for Design of Experiments (DoE) and data analysis. * Familiarity with GMP ...

Retro

PhD Candidate, Tissue Rejuvenation

Redwood City, CA · On-site

$96K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

Leverage AI/ML-guided design to support LNP formulation optimization * Execute cell culture, flow cytometry, and live animal work as the team needs. * Maintain timely, accurate experimental records ...

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Lnp Formulation information

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How much do lnp formulation jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for lnp formulation in the United States is $22.83, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $22.84 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in LNP formulation, and how can they be addressed?

Professionals in LNP (Lipid Nanoparticle) formulation often face challenges such as optimizing particle size and encapsulation efficiency, ensuring batch-to-batch consistency, and maintaining stability of formulations during scale-up. Addressing these challenges typically requires close collaboration with analytical, process development, and quality assurance teams, as well as staying current with advances in lipid chemistry and manufacturing technologies. Continuous learning and hands-on problem-solving are key to overcoming these hurdles and ensuring successful formulation outcomes.

What are the key skills and qualifications needed to thrive as an LNP formulation scientist?

To excel as an LNP (Lipid Nanoparticle) Formulation Scientist, a strong background in chemistry, pharmaceutical sciences, or related fields—typically with at least a bachelor's or master's degree—is essential. Familiarity with analytical instruments such as HPLC, DLS, and particle size analyzers, as well as experience using formulation and characterization software, is highly valuable. Attention to detail, problem-solving abilities, and effective teamwork are critical soft skills for designing and optimizing formulations. These competencies ensure the development of stable, effective lipid nanoparticles, which are crucial for drug delivery and therapeutic success.

What is LNP formulation?

LNP formulation refers to the process of creating lipid nanoparticles (LNPs), which are tiny particles made from lipids that can encapsulate and deliver drugs, such as mRNA, to specific cells in the body. This technology is crucial for the delivery of genetic medicines, including mRNA vaccines like those developed for COVID-19. The formulation process involves selecting the appropriate lipids, optimizing their ratios, and using specific techniques to assemble the nanoparticles to ensure they are stable, effective, and safe for use.

What is the difference between Lnp Formulation vs Pharmaceutical Scientist?

AspectLnp FormulationPharmaceutical Scientist
CredentialsDegree in pharmacy, chemistry, or pharmaceutical sciencesDegree in pharmacy, chemistry, or pharmaceutical sciences
Work EnvironmentLaboratories focused on drug delivery systemsResearch labs, manufacturing, or R&D departments
Industry UsageSpecialized in lipid nanoparticle formulations for drug deliveryBroader role in drug development, including formulation, testing, and analysis
Search/Comparison IntentOften compared for formulation expertise in drug deliveryMore general, encompassing various pharmaceutical development roles

In summary, Lnp Formulation specialists focus specifically on developing lipid nanoparticle delivery systems, requiring specialized knowledge in nanotechnology and formulation techniques. Pharmaceutical Scientists have a broader scope, working on various aspects of drug development, including formulation, testing, and regulatory compliance. Both roles often share similar educational backgrounds but differ in their specific focus and work environment.

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Lnp Formulation jobs near you
Infographic showing various Lnp Formulation job openings in the United States as of August 2026, with employment types broken down into 2% As Needed, 82% Full Time, 10% Part Time, 1% Temporary, 3% Contract, and 2% Nights. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution, with an average salary of $47,488 per year, or $22.8 per hour.

Scientist II, LNP

Crispr Therapeutics

South Boston, MA • On-site

$130K - $140K/yr

Full-time

Re-posted 6 days ago

Job description

Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
We are seeking a highly motivated Scientist II to join our LNP team. This is a critical, hands-on laboratory role focused on the design, development, and characterization of novel nanoparticle delivery systems.
The ideal candidate will have experience in lipid nanoparticle (LNP) design, formulation and characterization, with proven experience in designing novel solutions for encapsulation of different nucleic acid payloads (such as mRNA, siRNA, etc.). Experience in the space of target delivery or extra-hepatic delivery strategies is highly desirable. You will be part of a team responsible for driving the development of our delivery platform, from initial concept and screening through in vivo proof of concept studies.
Responsibilities
  • Design, formulate and optimize novel lipid nanoparticle (LNP) compositions through different production methods and scale.
  • Perform comprehensive analytical characterization of nanoparticles including but not limited to size, zeta potential, morphology, payload and lipid quantification, encapsulation efficiency, etc.
  • Develop and execute bioconjugation strategies to functionalize LNP surfaces with targeting ligands of different sizes or nature.
  • Analyze, interpret and present complex experimental data clearly and concisely at team and company meetings.
  • Work closely with cross-functional teams to design and execute experiments that evaluate formulation performance, toxicity, and efficacy.
  • Stay current with scientific literature, troubleshoot technical challenges, and proactively evaluate new technologies to improve our delivery platform.
  • Maintain meticulous and accurate electronic laboratory notebooks (ELN) and contribute to technical reports and regulatory filings.
  • Collaborate with IP counsels to support CRISPR Therapeutics patent applications and prosecutions

Minimum Qualifications
  • Degree in Pharmaceutical Sciences, Biomedical Engineering, Chemical Engineering, Chemistry, or a related field with PhD with 2-5 years of relevant experience or postdoctoral experience or non-PhD with 10-12+ years of relevant experience
  • Deep, hands-on experience in the formulation of lipid nanoparticles or similar non-viral delivery systems.
  • Demonstrated experience with encapsulating nucleic acids and associated analytical techniques.
  • Experience with bioconjugation chemistry and protein modification and purification.
  • Proficiency in nanoparticle characterization techniques.
  • Strong problem-solving skills and the ability to design experiments independently.
  • Excellent communication skills and a highly collaborative, team-oriented mindset.

Preferred Qualifications
  • Knowledge of LNP process development, scale-up and stability testing.
  • Experience with HPLC/UPLC for lipid and payload analysis.
  • Familiar with in vivo models for evaluating drug delivery systems.
  • Experience working in a fast-paced biotech or pharmaceutical industry environment.
  • Understanding of Design of Experiments (DoE) principles

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Scientist II: Base pay range of $130,000 to $140,000+ bonus, equity and benefits
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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