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Lnp Formulation Jobs in California (NOW HIRING)

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Scientist I

San Diego, CA · On-site

$48/hr

LNP Expertise: Minimum of 1-2 years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA). * Analytical Skills: Proficiency with ...

APN Software Services Inc

Scientist I

San Diego, CA · On-site

Resume must haves: - LNP (Lipid Nanoparticle) formulation. - industry/company experience, not accepting purely academic experience. Position Summary We are seeking a motivated and detail-oriented ...

Genentech

Director - Nanotechnology

San Diego, CA · On-site

$158K - $293K/yr

The Opportunity * Lead all research efforts for nanoparticle formulation, analytical ... Discover and optimize applications of novel lipids from diverse structural families for LNP ...

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Lnp Formulation information

What are some common challenges faced by professionals working in LNP formulation, and how can they be addressed?

Professionals in LNP (Lipid Nanoparticle) formulation often face challenges such as optimizing particle size and encapsulation efficiency, ensuring batch-to-batch consistency, and maintaining stability of formulations during scale-up. Addressing these challenges typically requires close collaboration with analytical, process development, and quality assurance teams, as well as staying current with advances in lipid chemistry and manufacturing technologies. Continuous learning and hands-on problem-solving are key to overcoming these hurdles and ensuring successful formulation outcomes.

What are the key skills and qualifications needed to thrive as an LNP Formulation Scientist, and why are they important?

To excel as an LNP (Lipid Nanoparticle) Formulation Scientist, a strong background in chemistry, pharmaceutical sciences, or related fields—typically with at least a bachelor's or master's degree—is essential. Familiarity with analytical instruments such as HPLC, DLS, and particle size analyzers, as well as experience using formulation and characterization software, is highly valuable. Attention to detail, problem-solving abilities, and effective teamwork are critical soft skills for designing and optimizing formulations. These competencies ensure the development of stable, effective lipid nanoparticles, which are crucial for drug delivery and therapeutic success.

What is LNP formulation?

LNP formulation refers to the process of creating lipid nanoparticles (LNPs), which are tiny particles made from lipids that can encapsulate and deliver drugs, such as mRNA, to specific cells in the body. This technology is crucial for the delivery of genetic medicines, including mRNA vaccines like those developed for COVID-19. The formulation process involves selecting the appropriate lipids, optimizing their ratios, and using specific techniques to assemble the nanoparticles to ensure they are stable, effective, and safe for use.

What is the difference between Lnp Formulation vs Pharmaceutical Scientist?

AspectLnp FormulationPharmaceutical Scientist
CredentialsDegree in pharmacy, chemistry, or pharmaceutical sciencesDegree in pharmacy, chemistry, or pharmaceutical sciences
Work EnvironmentLaboratories focused on drug delivery systemsResearch labs, manufacturing, or R&D departments
Industry UsageSpecialized in lipid nanoparticle formulations for drug deliveryBroader role in drug development, including formulation, testing, and analysis
Search/Comparison IntentOften compared for formulation expertise in drug deliveryMore general, encompassing various pharmaceutical development roles

In summary, Lnp Formulation specialists focus specifically on developing lipid nanoparticle delivery systems, requiring specialized knowledge in nanotechnology and formulation techniques. Pharmaceutical Scientists have a broader scope, working on various aspects of drug development, including formulation, testing, and regulatory compliance. Both roles often share similar educational backgrounds but differ in their specific focus and work environment.

What are popular job titles related to Lnp Formulation jobs in California? For Lnp Formulation jobs in California, the most frequently searched job titles are:
What job categories do people searching Lnp Formulation jobs in California look for? The top searched job categories for Lnp Formulation jobs in California are:
What cities in California are hiring for Lnp Formulation jobs? Cities in California with the most Lnp Formulation job openings:
Lnp Formulation jobs near you
Infographic showing various Lnp Formulation job openings in California as of July 2026, with employment types broken down into 1% As Needed, 81% Full Time, 14% Part Time, 1% Temporary, and 3% Contract. Highlights an 90% Physical, 2% Hybrid, and 8% Remote job distribution.
Lipid Nanoparticle Formulation Senior Scientist to Associate Director

Lipid Nanoparticle Formulation Senior Scientist to Associate Director

New Co.,

San Diego, CA • On-site

Other

Medical, Dental, Vision, Life, Retirement

Posted 15 days ago

Job description

Company Description

We are a privately held, stealth mode start-up biotechnology company developing lipid nanoparticle-based approaches to address unmet medical needs.


The Role

We are seeking an experienced hands-on and strategic Lipid Nanoparticle (LNP) Formulation Scientist to drive the design, execution, and analysis of Design of Experiments (DOE) to establish cutting-edge next-generation LNP platforms focusing on different disease areas. This role will play a critical part in developing, optimizing, and characterizing LNP systems for nucleic acid delivery in a fast-paced, collaborative research environment.


Key responsibilities

• Design, execute, and analyze DOE-based formulation experiments to develop and optimize novel LNP formulations

• Lead formulation innovation efforts, including lipid selection, composition optimization, and novel process development

• Perform LNP screening and characterization, including size, PDI, encapsulation efficiency, stability, and performance metrics

• Lead formulation process scale-up and technology transfer as needed

• Collaborate closely with cross-functional teams (biology, analytics, chemistry, and project management) to advance programs

• Maintain thorough experimental documentation and clearly communicate results and recommendations to stakeholders

• Contribute to troubleshooting formulation challenges and continuously improve experimental workflows


Professional experience and qualifications

•Senior Scientist, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 3-5 years relevant experience;

•Principal Scientist or Associate Director, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 6+ years relevant experience

• Strong hands-on experience with LNP formulations, including formulation development and optimization, process development and scaling-up

• Demonstrated expertise in DOE methodologies and statistical experimental design

• Extensive experience with LNP screening and analytical techniques

• Deep understanding of lipid-based delivery systems and formulation science principles

• Proven ability to work effectively in a team-oriented, fast-paced environment

• Strong problem-solving skills and ability to manage multiple priorities simultaneously

• Strong communication skills for presenting data and influencing technical decisions


What We Offer

• Opportunity to work at the forefront of LNP formulation innovation

• Collaborative, science-driven culture with high impact research

• Competitive compensation and benefits package, including health, dental, vision, and life insurance

• 401(k) with company match


Apply