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Lnp Formulation Jobs in California (NOW HIRING)

Analytical Scientist, Ph.D.

San Diego, CA · On-site

$110K - $140K/yr

Characterize LNP drug product attributes including lipid composition and ratios, encapsulation ... Support formulation development, process development, and stability studies by providing timely ...

Characterize LNP drug product attributes including lipid composition and ratios, encapsulation ... Support formulation development, process development, and stability studies by providing timely ...

Showing results 21-36

Lnp Formulation information

What is LNP formulation?

LNP formulation refers to the process of creating lipid nanoparticles (LNPs), which are tiny particles made from lipids that can encapsulate and deliver drugs, such as mRNA, to specific cells in the body. This technology is crucial for the delivery of genetic medicines, including mRNA vaccines like those developed for COVID-19. The formulation process involves selecting the appropriate lipids, optimizing their ratios, and using specific techniques to assemble the nanoparticles to ensure they are stable, effective, and safe for use.

What are the key skills and qualifications needed to thrive as an LNP formulation scientist?

To excel as an LNP (Lipid Nanoparticle) Formulation Scientist, a strong background in chemistry, pharmaceutical sciences, or related fields—typically with at least a bachelor's or master's degree—is essential. Familiarity with analytical instruments such as HPLC, DLS, and particle size analyzers, as well as experience using formulation and characterization software, is highly valuable. Attention to detail, problem-solving abilities, and effective teamwork are critical soft skills for designing and optimizing formulations. These competencies ensure the development of stable, effective lipid nanoparticles, which are crucial for drug delivery and therapeutic success.

What are some common challenges faced by professionals working in LNP formulation, and how can they be addressed?

Professionals in LNP (Lipid Nanoparticle) formulation often face challenges such as optimizing particle size and encapsulation efficiency, ensuring batch-to-batch consistency, and maintaining stability of formulations during scale-up. Addressing these challenges typically requires close collaboration with analytical, process development, and quality assurance teams, as well as staying current with advances in lipid chemistry and manufacturing technologies. Continuous learning and hands-on problem-solving are key to overcoming these hurdles and ensuring successful formulation outcomes.

What is the difference between Lnp Formulation vs Pharmaceutical Scientist?

AspectLnp FormulationPharmaceutical Scientist
CredentialsDegree in pharmacy, chemistry, or pharmaceutical sciencesDegree in pharmacy, chemistry, or pharmaceutical sciences
Work EnvironmentLaboratories focused on drug delivery systemsResearch labs, manufacturing, or R&D departments
Industry UsageSpecialized in lipid nanoparticle formulations for drug deliveryBroader role in drug development, including formulation, testing, and analysis
Search/Comparison IntentOften compared for formulation expertise in drug deliveryMore general, encompassing various pharmaceutical development roles

In summary, Lnp Formulation specialists focus specifically on developing lipid nanoparticle delivery systems, requiring specialized knowledge in nanotechnology and formulation techniques. Pharmaceutical Scientists have a broader scope, working on various aspects of drug development, including formulation, testing, and regulatory compliance. Both roles often share similar educational backgrounds but differ in their specific focus and work environment.

What cities in California are hiring for Lnp Formulation jobs?

Cities in California with the most Lnp Formulation job openings:

Infographic showing various Lnp Formulation job openings in California as of August 2026, with employment types broken down into 82% Full Time, and 18% Contract. Highlights an 94% In-person, and 6% Remote job distribution.

Associate Director/Director, Formulation & Downstream Process Development

Pivotal

San Diego, CA • On-site

$65 - $100/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 17 days ago


Job description

Research Associate, Formulation Development

Location: San Diego, CA

Job Type: Full-Time, Onsite

About Us

We are an innovative, stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing.

Job Summary

We are seeking a highly motivated and skilled individual to join our team as a Research Associate in Formulation Development. The successful candidate will be responsible for designing, executing, analyzing, and making recommendations on research protocols for lipid nanoparticle (LNP) drug delivery systems aimed at gene editing. Title level and salary will be commensurate with experience.

Responsibilities
  • Develop lipid nanoparticle (LNP) formulations for gene editing applications.
  • Conduct experiments to optimize formulation parameters such as particle size, encapsulation efficiency, and stability.
  • Optimize production processes to improve yields and scalability.
  • Troubleshoot and resolve issues related to formulation processes.
  • Perform analytical characterization of LNPs using techniques such as dynamic light scattering (DLS), zeta potential measurement, and electron microscopy.
  • Support in vitro and in vivo studies to evaluate the efficacy and safety of LNP formulations.
  • Collaborate with preclinical and clinical teams to ensure successful translation of formulations.
  • Maintain accurate and detailed laboratory records.
  • Prepare technical reports and presentations to communicate findings.
  • Stay current with advancements in LNP technologies and methodologies.
Qualifications
  • Bachelor's degree or higher in Chemistry, Pharmaceutics, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
  • 3+ years of experience in pharmaceutical formulation, with a focus on lipid nanoparticle drug delivery systems.
  • Experience with techniques such as DLS, zeta potential measurement, and other analytical tools used in nanoparticle characterization.
  • Strong analytical and problem-solving skills.
  • Excellent communication and teamwork abilities.
  • Ability to work independently and manage multiple tasks effectively.
Preferred Qualifications
  • GMP production experience.
  • Familiarity with regulatory requirements and quality control in bioprocessing.
Benefits
  • Competitive salary, equity, and benefits package.
  • Opportunities for professional growth and development.
  • Fast paced collaborative and innovative work environment.
  • We offer an exceptional benefits package to include Medical, Dental, Vision, Life, Disability, a 401k Match of 4%, Paid Time Off and Equity.
Equal Opportunity Employer

We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

Salary Range

$65,000 - $100,000

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