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Lead It Infrastructure Engineer Jobs (NOW HIRING)

Certara

Sr. IT Infrastructure Engineer

Radnor, PA · On-site

$97K - $133K/yr

Lead or participate in implementations across cloud, networking, virtualization, identity, and ... IT operations or infrastructure engineering within medium-to-large enterprises. * 10+ years of ...

Grant PUD

IT Infrastructure Engineer I-III

Ephrata, WA · On-site

$112K - $192K/yr

Position Summary IT Infrastructure Engineer I Under general supervision, this position performs professional-level infrastructure systems, analysis, configuration, documentation, testing ...

CAR-FRESHNER

IT Infrastructure Engineer

Watertown, NY · On-site

$90K - $130K/yr

The IT Infrastructure Engineer is a hands-on technical owner responsible for the day-to-day operation, reliability, security, and performance of the network infrastructure and business-critical ...

Fabergent

IT Infrastructure Engineer

Miami, FL · On-site

... experience in corporate infrastructure environment Knowledge and experience installing and ... IT team and the ability to assist and teach less advanced team members Must be capable of ...

American Trim

IT Infrastructure Engineer

Sidney, OH · On-site

Under the direction of the IT Director, the IT Infrastructure Engineer is a hands on leader responsible for the design, installation, analysis, troubleshooting, and maintenance of all American Trim ...

MacLean-Fogg

IT Infrastructure Manager

Mundelein, IL

Lead efforts to optimize infrastructure resources, increasing system efficiency, reliability, and ... Oversee daily IT infrastructure operations, ensuring stable, secure, and scalable systems across ...

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Lead It Infrastructure Engineer information

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$46.5K

$127.1K

$182K

How much do lead it infrastructure engineer jobs pay per year?

As of Jun 23, 2026, the average yearly pay for lead it infrastructure engineer in the United States is $127,066.00, according to ZipRecruiter salary data. Most workers in this role earn between $107,500.00 and $141,000.00 per year, depending on experience, location, and employer.

How does a Lead IT Infrastructure Engineer typically collaborate with other departments to support business objectives?

As a Lead IT Infrastructure Engineer, you will frequently partner with teams across the organization, such as application development, cybersecurity, and operations. Your role involves translating business requirements into scalable infrastructure solutions and ensuring that new technologies align with organizational goals. You'll participate in cross-functional meetings, lead infrastructure projects, and provide technical guidance to both IT staff and non-technical stakeholders. Strong communication and project management skills are essential for balancing technical needs with business priorities.

What are the key skills and qualifications needed to thrive as a Lead IT Infrastructure Engineer, and why are they important?

To thrive as a Lead IT Infrastructure Engineer, you need deep expertise in network architecture, server administration, cloud technologies, and a relevant degree or equivalent experience. Familiarity with systems such as VMware, Microsoft Azure or AWS, and certifications like CCNP, MCSE, or AWS Certified Solutions Architect are highly valued. Leadership, problem-solving, and effective communication are essential soft skills for managing teams and complex projects. These skills ensure the reliability, security, and scalability of IT systems critical to organizational operations.

What does a Lead IT Infrastructure Engineer do?

A Lead IT Infrastructure Engineer is responsible for overseeing the design, implementation, and management of an organization's IT infrastructure, including servers, networks, and storage systems. They lead a team of engineers, ensure systems are secure and reliable, and coordinate with other departments to support business goals. This role often involves planning upgrades, troubleshooting complex issues, and maintaining high availability and performance of critical IT services.
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What job categories do people searching Lead It Infrastructure Engineer jobs look for? The top searched job categories for Lead It Infrastructure Engineer jobs are:
Lead It Infrastructure Engineer jobs near you
Infographic showing various Lead It Infrastructure Engineer job openings in the United States as of June 2026, with employment types broken down into 97% Full Time, 1% Part Time, and 2% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $127,066 per year, or $61.1 per hour.
Sr. IT Infrastructure Engineer

Sr. IT Infrastructure Engineer

Certara

Radnor, PA • On-site

$97K - $133K/yr

Full-time

Posted 7 days ago

Job description

Overview
Certara accelerates the potential of bringing medicines to market and to patients using biosimulation software, technology, and services to transform traditional drug discovery and development. Our clients include more than 2,400 biopharmaceutical companies, academic institutions, and regulatory agencies across 70 countries.
As a Senior IT Infrastructure Engineer at Certara, you are part of a global, fast-paced IT organization whose mission is to deliver capable, resilient, world-class technology services to professional services, software development, and corporate business units. The team ensures employees worldwide have secure, reliable access to the systems and platforms they need to perform at the highest level in service of our customers.
IT Infrastructure spans multiple technical disciplines-including data center, cloud, networking, security, systems, and endpoint technologies, working together to create a cohesive and integrated technology stack that supports global business growth. The Senior IT Infrastructure Engineer serves as the technical owner of one or more core infrastructure platforms (including Citrix Cloud, Cisco Meraki, Azure Cloud Infrastructure, and Active Directory), ensuring operational excellence, scalability, and resiliency.
This is a hands-on, senior-level engineering role responsible for designing, maintaining, and optimizing infrastructure services in a hybrid and cloud-forward environment. Daily responsibilities include developing and maintaining operating procedures, executing maintenance routines, and providing Level 3 technical escalation support across supported technologies. The role also supports mentoring and knowledge development of global operations and service desk team members.
The ideal candidate brings a strong understanding of enterprise infrastructure architecture and how to build for scale in a regulated environment. In addition to technical execution, this role is responsible for creating documentation, operational controls, and governance processes that align with compliance frameworks including SOX, ISO 9001, ISO 27001, and SOC 2.
*The preference is for candidates on the East Coast of the US*
Responsibilities
Infrastructure Operations Management
  • Administer and optimize:
    • Citrix Cloud environments
    • Cisco Meraki networking infrastructure
    • Microsoft Azure cloud Infrastructure
    • Active Directory (on-prem & hybrid)
    • Utilize monitoring, management, and capacity planning to ensure performance, availability, and reliability.
  • Identify and remediate recurring systemic issues to reduce repeat service desk incidents.
  • Provide level 3 escalation support to Service Desk and Operations Engineers within defined SLAs.
  • Maintain and update detailed infrastructure design and operational documentation to support a distributed global team.
  • Ensure infrastructure adheres to security, compliance, and governance standards.

Research & Continuous Improvement
  • Partner with business and technical stakeholders to identify opportunities to improve operational effectiveness through technology.
  • Evaluate and recommend infrastructure enhancements, service improvements, or re-architecture initiatives.
  • Contribute to infrastructure standardization, automation, and modernization strategies.
  • Proactively assess capacity, scalability, performance, and resiliency improvements.

Project Execution
  • Execute infrastructure initiatives and modernization projects using Agile methodologies.
  • Lead or participate in implementations across cloud, networking, virtualization, identity, and endpoint delivery platforms.
  • Support cloud migrations, infrastructure upgrades, and platform consolidations.
  • Integrate DevOps and automation practices into infrastructure deployment and management workflows.

Qualifications
Qualifications
  • 7+ years of experience in IT operations or infrastructure engineering within medium-to-large enterprises.
  • 10+ years of experience supporting life sciences, professional services, and/or software development organizations.
  • Advanced experience with:
    • Citrix Cloud
    • Cisco Meraki Microsoft Azure Infrastructure (IaaS, networking, identity, storage)
    • Active Directory (Hybrid AD, Group Policy, Azure AD / Entra ID)
  • Experience managing Windows and Linux Server OS in hybrid data center environments.
  • Strong experience with backup and disaster recovery solutions (on-prem and cloud).
  • SME-level experience with monitoring and incident management systems.
  • Experience across multiple vendor stacks including:
  • Microsoft Azure
  • Networking and telecommunications management experience required.
  • Exposure to DevOps tooling supporting CI/CD pipelines.
  • Scripting and automation experience in one or more languages (PowerShell, Python, Bash, etc.). Strong written and verbal communication skills.
  • Highly organized with demonstrated experience documenting complex technical systems.
  • Strong analytical skills and ability to resolve complex technical problems.
  • Ability to collaborate effectively in cross-functional global teams.

Preferred Qualifications
  • Infrastructure architecture & design
  • Incident & problem management
  • Capacity planning
  • Systems integration
  • Automation mindset
  • Continuous improvement orientation
  • Global collaboration
  • Live on the East Coast of the United States

Certara bases all employment-related decision on merit, taking into consideration qualifications, skills, achievement, and performance. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.

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