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It Infrastructure Program Manager Jobs in Wisconsin

We are in search of a proactive and knowledgeable IT Infrastructure Manager to lead the development ... Through our nVent in Action matching program, we provide funds to nonprofit and educational ...

We are in search of a proactive and knowledgeable IT Infrastructure Manager to lead the development ... Through our nVent in Action matching program, we provide funds to nonprofit and educational ...

Principal IT Program Manager

Waukesha, WI · On-site

$116K - $116K/yr

The Principal IT Program Manager partners closely with executive leadership, product organizations, engineering teams, cybersecurity, infrastructure, enterprise architecture, and business ...

In the role of IT Program Manager working in Milwaukee, WI you will be part of the global IT Project Delivery team . This position is accountable for managing large scale multinational, typically ...

In the role of IT Program Manager working in Milwaukee, WI you will be part of the global IT Project Delivery team . This position is accountable for managing large scale multinational, typically ...

In the role of IT Program Manager working in Milwaukee, WI you will be part of the global IT Project Delivery team . This position is accountable for managing large scale multinational, typically ...

In the role of IT Program Manager working in Milwaukee, WI you will be part of the global IT Project Delivery team . This position is accountable for managing large scale multinational, typically ...

In the role of IT Program Manager working in Milwaukee, WI you will be part of the global IT Project Delivery team . This position is accountable for managing large scale multinational, typically ...

... IT Infrastructure projects for our Fortune 500 client. The ideal candidate will collaborate with ... Manage infrastructure programs, including hardware/software upgrades, IT design implementations ...

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It Infrastructure Program Manager information

What is the difference between It Infrastructure Program Manager vs Network Engineer?

AspectIt Infrastructure Program ManagerNetwork Engineer
CertificationsITIL, PMP, CompTIA Security+CCNA, CCNP, CompTIA Network+
Work EnvironmentProject management, strategic planning, cross-department collaborationNetwork design, troubleshooting, implementation
Employer & Industry UsageIT departments, managed service providers, large enterprisesTelecommunications, data centers, corporate IT teams

The It Infrastructure Program Manager oversees large-scale IT projects, focusing on planning and coordination, while a Network Engineer specializes in designing and maintaining network systems. Both roles require technical certifications and work within IT environments, but their daily responsibilities and focus areas differ significantly.

What does an IT Infrastructure Program Manager do?

An IT Infrastructure Program Manager oversees and coordinates large-scale technology projects related to an organization's IT infrastructure, such as networks, servers, data centers, and cloud environments. They ensure that projects are delivered on time, within budget, and according to technical and business requirements. Their responsibilities include project planning, stakeholder communication, risk management, resource allocation, and aligning IT initiatives with organizational goals. They typically work closely with technical teams, vendors, and senior management to ensure successful program outcomes.

What are some typical challenges faced by IT Infrastructure Program Managers when coordinating cross-functional teams?

IT Infrastructure Program Managers often navigate complex projects involving multiple departments such as networking, security, and operations. One common challenge is aligning varying priorities and timelines across these teams, which requires strong communication and negotiation skills. Additionally, they must manage resource constraints and adapt quickly to evolving technical requirements or unexpected issues. Building effective relationships and fostering collaboration are key to overcoming these hurdles and ensuring project success.

What are the key skills and qualifications needed to thrive as an IT Infrastructure Program Manager?

To thrive as an IT Infrastructure Program Manager, you need strong project management skills, a deep understanding of IT systems and networks, and experience with large-scale infrastructure deployments, often supported by a bachelor's degree in a related field. Familiarity with tools such as Microsoft Project, ITIL frameworks, and certifications like PMP or ITIL are highly valued. Outstanding leadership, communication, and problem-solving abilities help you coordinate diverse teams and manage stakeholder expectations. These skills and qualities are crucial for delivering complex technology projects on time and within budget while ensuring alignment with organizational goals.
What are popular job titles related to It Infrastructure Program Manager jobs in Wisconsin? For It Infrastructure Program Manager jobs in Wisconsin, the most frequently searched job titles are:
What cities in Wisconsin are hiring for It Infrastructure Program Manager jobs? Cities in Wisconsin with the most It Infrastructure Program Manager job openings:
Infographic showing various It Infrastructure Program Manager job openings in Wisconsin as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 18% Part Time, 1% Temporary, and 2% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution.

Director, IT Infrastructure

Arrowhead Pharmaceuticals

Madison, WI

Full-time

Re-posted 17 days ago


Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Director of IT Infrastructure is a leadership role responsible for the strategy, design, implementation, and ongoing operations of the company's enterprise IT infrastructure. This leader will oversee a geographically distributed environment spanning on-premises and public cloud platforms (Microsoft Azure and Amazon Web Services). The Director will lead a team of infrastructure staff to support business needs, drive modernization initiatives, and ensure the reliability and scalability of all infrastructure services in alignment with pharmaceutical industry standards.

This role is based onsite 5 days a week from one of Arrowhead's office locations.

Responsibilities

  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
  • Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
  • Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
  • Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
  • Manage a Microsoft Active Directory environment
  • Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
  • Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
  • Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
  • Oversee server patching and configuration management standards across the enterprise.
  • Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
  • Ensure all infrastructure platforms and processes comply with regulatory requirements as applicable.
  • Support internal and external audits by providing documentation, evidence, and technical guidance related to infrastructure controls.
  • Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
  • Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
  • Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
  • Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.

Requirements

  • Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
  • 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
  • Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
  • Demonstrated experience managing Microsoft Active Directory.
  • Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
  • Experience managing multi-site enterprise IT environments in a regulated industry.
  • Proven track record of building, leading, and developing high-performing infrastructure teams.
  • Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
  • Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).

Preferred

  • Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
  • Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
  • Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
  • Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
  • Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
  • Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
  • Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
  • Data-driven decision-making and a continuous improvement mindset.
Wisconsin pay range
$190,000—$210,000 USD
California pay range
$210,000—$230,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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