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It Infrastructure Manager Jobs in Madison, WI (NOW HIRING)

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IT Infrastructure Administrator

Madison, WI · On-site

Manage the daily health of the macOS fleet using Jamf Pro by monitoring Automated Device Enrollment tokens and troubleshooting failed pre-stage enrollments to ensure zero-touch deployment success.

Freedom Graphic Systems

IT Network Administrator

Milton, WI · On-site

$60K - $80K/yr

The Network Administrator operates under the direction of the IT Infrastructure Manager and works closely with other IT staff. They have a strong understanding of network infrastructure and endpoints ...

New

Realta Fusion Inc.

Information Technology Manager

Madison, WI · On-site

$95K - $117K/yr

We are seeking an Information Technology Manager to oversee and support the company's internal IT operations, infrastructure, cybersecurity, and vendor management as we continue to scale. This role ...

Quartz

Manager, Technology Operations

Madison, WI · On-site

$116K - $146K/yr

Quartz Health Solutions is seeking a Manager, Technology Operations (Tech Ops) to lead a team ... Or high school equivalency with 11+ years of experience in IT infrastructure, technical support ...

SmartIPlace

REQ :: IT Project Manager

Madison, WI · On-site

$50 - $55/hr

Skills Required * 10 years - Experience managing large & complex IT projects, leading teams, supporting stakeholders, and implementing IT infrastructure * 10 years - Knowledge and direct experience ...

Quartz

Manager, Technology Operations

Madison, WI · On-site

$116K - $146K/yr

Quartz Health Solutions is seeking a Manager, Technology Operations (Tech Ops) to lead a team ... Or high school equivalency with 11+ years of experience in IT infrastructure, technical support ...

FGS-WI LLC

Network Administrator

Milton, WI · On-site

$60K - $80K/yr

The Network Administrator operates under the direction of the IT Infrastructure Manager and works closely with other IT staff. They have a strong understanding of network infrastructure and endpoints ...

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All JobsIt Infrastructure JobsIt Infrastructure Manager JobsIt Infrastructure Manager Jobs in Madison, WI

It Infrastructure Manager information

See Madison, WI salary details

$69.5K

$124.6K

$182.9K

How much do it infrastructure manager jobs pay per year?

As of Aug 22, 2026, the average yearly pay for it infrastructure manager in Madison, WI is $124,590.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,700.00 and $147,600.00 per year, depending on experience, location, and employer.

What does an IT infrastructure manager do?

An IT Infrastructure Manager is responsible for overseeing the design, implementation, and maintenance of an organization's technology infrastructure, including servers, networks, and data storage. They ensure that all IT systems are secure, reliable, and meet the company's needs. This role involves managing IT staff, coordinating with other departments, and planning for future technology upgrades or expansions. Additionally, IT Infrastructure Managers are often responsible for disaster recovery planning and ensuring compliance with relevant regulations.

What are the key skills and qualifications needed to thrive as an IT infrastructure manager?

To thrive as an IT Infrastructure Manager, you need a solid background in IT systems, network administration, and project management, often supported by a bachelor's degree in computer science or related fields. Familiarity with virtualization platforms, cloud services (like AWS or Azure), and certifications such as ITIL or Cisco are typically essential. Leadership, problem-solving, and strong communication skills help you effectively manage teams and coordinate with stakeholders. These skills are crucial for ensuring reliable IT operations, efficient project delivery, and alignment with organizational goals.

How does an IT infrastructure manager typically collaborate with other departments to ensure seamless technology operations?

An IT Infrastructure Manager works closely with various departments such as security, application development, and business operations to ensure that technology systems align with organizational needs. This involves regular meetings to understand requirements, coordinating system upgrades or migrations, and addressing any technical challenges that may impact other teams. Effective communication and cross-functional collaboration are essential, as the manager often acts as a bridge between technical staff and non-technical stakeholders. Building strong relationships helps proactively identify issues and implement solutions that support the entire organization's objectives.

What is the difference between It Infrastructure Manager vs Network Administrator?

AspectIt Infrastructure ManagerNetwork Administrator
ResponsibilitiesOversees entire IT infrastructure, including servers, storage, and network systems; manages teams and strategic planningMaintains and supports network hardware, software, and security; ensures network connectivity and performance
CertificationsITIL, PMP, Cisco, Microsoft certifications often preferredCCNA, CompTIA Network+, Cisco certifications
Work EnvironmentLeadership roles in IT departments, strategic planning, vendor managementHands-on technical work, troubleshooting, network configuration

The main difference is that an It Infrastructure Manager oversees the entire IT infrastructure and manages teams, while a Network Administrator focuses on maintaining and supporting network systems. The Infrastructure Manager has broader strategic responsibilities, whereas the Network Administrator handles day-to-day network operations.

What are the 4 types of IT infrastructure?

The four main types of IT infrastructure are hardware infrastructure, software infrastructure, network infrastructure, and data infrastructure. An IT Infrastructure Manager oversees these components to ensure reliable and secure technology operations within an organization. Understanding these types helps in designing, managing, and maintaining effective IT environments.

What is the role of IT infrastructure management?

IT infrastructure management involves overseeing and maintaining an organization's hardware, software, networks, and data centers to ensure reliable and secure IT operations. It includes tasks such as system deployment, monitoring, troubleshooting, and implementing security protocols, often requiring knowledge of tools like network management systems and certifications such as ITIL or CompTIA. The role ensures that technology supports business objectives efficiently and securely.

What is the role of IT infrastructure manager?

An IT infrastructure manager oversees the planning, implementation, and maintenance of an organization’s IT systems, including networks, servers, and hardware. They ensure the reliability, security, and efficiency of technology infrastructure, often managing teams and working with tools like cloud platforms and network security protocols.

What are the most commonly searched types of It Infrastructure jobs in Madison, WI?

The most popular types of It Infrastructure jobs in Madison, WI are:

What job categories do people searching It Infrastructure Manager jobs in Madison, WI look for?

The top searched job categories for It Infrastructure Manager jobs in Madison, WI are:

What cities near Madison, WI are hiring for It Infrastructure Manager jobs?

Cities near Madison, WI with the most It Infrastructure Manager job openings:

It Infrastructure Manager jobs near you
Infographic showing various It Infrastructure Manager job openings in Madison, WI as of August 2026, with employment types broken down into 84% Full Time, 13% Part Time, and 3% Contract. Highlights an 83% Physical, 2% Hybrid, and 15% Remote job distribution, with an average salary of $124,590 per year, or $59.9 per hour.

Director, IT Infrastructure

Arrowhead Pharmaceuticals

Madison, WI • On-site

Full-time

Re-posted 26 days ago

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Director of IT Infrastructure is a leadership role responsible for the strategy, design, implementation, and ongoing operations of the company's enterprise IT infrastructure. This leader will oversee a geographically distributed environment spanning on-premises and public cloud platforms (Microsoft Azure and Amazon Web Services). The Director will lead a team of infrastructure staff to support business needs, drive modernization initiatives, and ensure the reliability and scalability of all infrastructure services in alignment with pharmaceutical industry standards.

This role is based onsite 5 days a week from one of Arrowhead's office locations.

Responsibilities

  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
  • Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
  • Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
  • Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
  • Manage a Microsoft Active Directory environment
  • Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
  • Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
  • Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
  • Oversee server patching and configuration management standards across the enterprise.
  • Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
  • Ensure all infrastructure platforms and processes comply with regulatory requirements as applicable.
  • Support internal and external audits by providing documentation, evidence, and technical guidance related to infrastructure controls.
  • Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
  • Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
  • Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
  • Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.

Requirements

  • Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
  • 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
  • Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
  • Demonstrated experience managing Microsoft Active Directory.
  • Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
  • Experience managing multi-site enterprise IT environments in a regulated industry.
  • Proven track record of building, leading, and developing high-performing infrastructure teams.
  • Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
  • Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).

Preferred

  • Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
  • Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
  • Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
  • Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
  • Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
  • Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
  • Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
  • Data-driven decision-making and a continuous improvement mindset.
Wisconsin pay range
$190,000—$210,000 USD
California pay range
$210,000—$230,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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