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Internship Downstream Process Development Scientist Jobs

Legend Biotech USA, Inc.

The successful candidate will drive scientific excellence in downstream processing (DSP)-including ... Direct the development and optimization of downstream processes including and not limited to ...

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How much do internship downstream process development scientist jobs pay per hour?

As of Aug 21, 2026, the average hourly pay for internship downstream process development scientist in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What does an internship downstream process development scientist do?

An Internship Downstream Process Development Scientist works in the biopharmaceutical industry, assisting with the development and optimization of processes that purify biological products such as proteins, antibodies, or vaccines after they are produced by cells. Their role often involves supporting laboratory experiments, analyzing samples, and documenting results to improve the efficiency and scalability of downstream processes like filtration and chromatography. Interns in this position gain hands-on experience with cutting-edge technologies and learn about regulatory requirements and industry standards. This role helps prepare students or recent graduates for a career in process development or biomanufacturing.

What types of projects and responsibilities can an internship downstream process development scientist expect to work on?

As an Internship Downstream Process Development Scientist, you can expect to be involved in hands-on laboratory work focusing on the purification and characterization of biopharmaceutical products. Typical responsibilities include preparing buffer solutions, operating chromatography and filtration systems, analyzing samples using various analytical techniques, and documenting experimental results. Interns often collaborate with experienced scientists and engineers, contributing to process optimization and troubleshooting. The role provides valuable exposure to industry-standard procedures and the opportunity to develop technical skills in a team-oriented environment.

What are the key skills and qualifications needed to thrive as an internship downstream process development scientist, and why are they important?

To thrive as an Internship Downstream Process Development Scientist, you need foundational knowledge in biochemistry, molecular biology, or chemical engineering, often supported by ongoing or recent enrollment in a relevant degree program. Familiarity with laboratory techniques such as chromatography, filtration, and analytical instruments, as well as experience with lab management software, is typically expected. Attention to detail, problem-solving abilities, and effective teamwork are standout soft skills in this role. These skills and qualifications are crucial for conducting reliable experiments, analyzing data, and contributing to the optimization of bioprocesses in a collaborative research environment.
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Internship Downstream Process Development Scientist jobs near you
Infographic showing various Internship Downstream Process Development Scientist job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $80,420 per year, or $38.7 per hour.

Scientist I, Downstream Process Development

Abzena Inc.

San Diego, CA • On-site

Full-time

Re-posted 15 days ago

Job description

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.
Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.
We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.
We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.
The Scientist I leads all aspects of purification process development from process definition to process characterization for client programs. Manages a team of associates to design and execute a series of experiments to drive program objectives. May propose new processes and technologies which lead to the acceleration of projects or drive business value. Serves as a client interface subject matter expert in purification. Functions as an advisor to management on technical matters.
Responsibilities
  • Applies extensive practical and theoretical scientific or engineering expertise to the development of scalable and robust purification processes.
  • With minimal direction, manages, designs and conducts a series of specific scientific experiments which contribute to client program objectives. Leads troubleshooting of processes, instrumentation and equipment.
  • Functions as a technical lead in technology transfer from process development to clinical cGMP manufacturing including definition of bill of materials, process definition and batch record review. Serves as a process development lead during downstream operations. Provides technical troubleshooting and may recommend process equipment improvements.
  • Designs and performs a series of bench scale experiments related to purification development and scale up such as depth filtration, sterile membrane filtration, tangential flow filtration, viral filtration and chromatography.
  • May propose new technologies which lead to the acceleration of programs. Proactively identifies purification challenges and drives solutions.
  • Consistently demonstrates a high level of scientific leadership.
  • Leads and mentors a team of associates to effectively execute a series of experiments designed to meet the goals and objectives of client programs. This includes production of materials under standards and practices required for toxicology studies.
  • Collaborates with cell line development, cell culture development, analytical method development, and manufacturing sciences and technology for achievement of program objectives.
  • Effective communicator of ideas, project goals and results across functions and to clients.
  • Functions as an advisor to top management on technical matters.
  • Authors and reviews technical documents including experimental plans, development reports, toxicology production reports, process optimization reports, scale down model protocols and reports, and process characterization protocols and reports.
  • Provides detailed observations, analyzes data, interprets results and develops scientifically-sound solutions.
  • Acts as a Subject Matter Expert (SME) to train others in areas of expertise. Assists and offers guidance to the Process Development group and Manufacturing group as necessary to train in correlated processes.
  • This role has direct reports. Will be responsible for guiding and mentoring junior staff including conducting performance evaluations and encouraging career development within the organization.
  • Oversees production schedules, materials, equipment and resource requirements.
  • Maintains records to comply with regulatory requirements.
  • Operates and ensures appropriate maintenance of production equipment as it relates to downstream production activities.
  • Represents departmental activities as needed, including project teams, task forces, audits and business or technical meetings with outside groups.
  • Develops effective working relationships with both internal and external partners.
  • Operates to the highest ethical and moral standards.
  • Complies with Abzena's policies and procedures.
  • Communicates effectively with clients, supervisors, colleagues and staff.
  • Participates effectively as a team player in all aspects of Abzena's business.
  • Adheres to quality standards set by regulations and Abzena policies, procedures, and mission.
  • Performs other duties as assigned.

Qualifications
  • BS, MS, or PhD degree in applicable scientific field.
  • Minimum of 9 years directly related experience with a BS degree; Minimum of 6 years directly related experience with an MS degree; Minimum of 2 years' experience with a PhD degree.
  • Knowledge of purification concepts including biochemical properties, protein production, characterization, and scaling of purification processes.
  • Knowledge and skills in relation to purification process steps including depth filtration harvest, chromatography, tangential flow filtration, and viral clearance considerations.
  • Understanding of purification process design limits for implementation in a clinical manufacturing environment.
  • Knowledge of design of experiments using statistical software for increased purity in relation to operation of multivariate experiments.
  • Knowledge of quantitative and qualitative analytical methods and interpretation of analytical data.
  • Ability to organize workload, oversee direct reports, and relevant resource requirements.
  • Skills in leadership, including time management and planning.
  • Knowledge cGMP requirements.
  • Ability to observe technical issues with troubleshooting knowledge of process and equipment problems.
  • Ability to operate complex systems and equipment and optimize their use in manufacturing in accordance with defined goals.
  • Ability to mentor and train purification associates in process transfer, scale-up, from scientific and engineering perspective.

$110,000 - $135,000 a year
FLSA: Exempt
Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.

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