ZipRecruiter

Log In

1

Infrastructure Manager Jobs in San Ramon, CA (NOW HIRING)

Meta

Finance Manager, Infrastructure

Menlo Park, CA

$195K/yr

The Infrastructure Finance team manages Meta's capital and operating expenses for Infrastructure which is one of the largest areas of investment at the company as we invest in advanced AI ...

Meta

Infrastructure Materials Manager

Menlo Park, CA

$115K/yr

The Infrastructure Materials Manager would engage various internal customers, manage material inventory ordering & fulfillment, manage material escalation, coordinate execution activities, enable ...

Meta

Manager, Infrastructure OEM Operations

Menlo Park, CA · On-site

$179K - $249K/yr

Meta is seeking an experienced sourcing and commodity management leader to oversee infrastructure OEM operations supporting Meta's global data center and hardware supply chain. In this role, you will ...

New

next page

Showing results 1-20

All JobsInfrastructure JobsInfrastructure Manager JobsInfrastructure Manager Jobs in San Ramon, CA

Infrastructure Manager information

See San Ramon, CA salary details

$90K

$172.1K

$221.3K

How much do infrastructure manager jobs pay per year?

As of Jul 20, 2026, the average yearly pay for infrastructure manager in San Ramon, CA is $172,129.00, according to ZipRecruiter salary data. Most workers in this role earn between $126,300.00 and $220,200.00 per year, depending on experience, location, and employer.

What skills are needed for infrastructure management?

Infrastructure managers need strong technical skills in network, server, and cloud technologies, along with project management and problem-solving abilities. Knowledge of cybersecurity, system administration, and relevant certifications like ITIL or Cisco can enhance effectiveness. Effective communication and leadership skills are also essential for coordinating teams and stakeholders.

What is the highest paying manager position?

The highest paying manager positions are often executive roles such as Chief Executive Officer (CEO), Chief Operating Officer (COO), or Chief Financial Officer (CFO), with salaries significantly higher than other management roles. Among non-executive managers, senior roles like Vice President or Director in specialized fields such as technology, finance, or healthcare tend to have the highest compensation, especially with relevant certifications and extensive experience.

What Does an Infrastructure Manager Do?

An infrastructure manager works with an organization’s IT department to plan, design, and implement the technology ecosystem. Your responsibilities in this career include a range of other tasks to prepare and maintain the IT infrastructure. Duties can involve working with either hardware, software, or both, depending on the size of the business. You can also specialize in a particular aspect of the network. Your primary goal is to guarantee the security and integrity of the system. Some infrastructure manager positions also focus on budget, periodic reviews, or negotiations with vendors.

How much do infrastructure managers make in the US?

Infrastructure managers in the US typically earn a median annual salary of around $100,000 to $130,000, depending on experience, industry, and location. Senior roles or those with specialized skills in network, cloud, or systems management can earn higher salaries, often exceeding $150,000 annually.

What are some common challenges an Infrastructure Manager faces when overseeing hybrid cloud environments?

Infrastructure Managers frequently encounter challenges in balancing on-premises and cloud-based resources, ensuring seamless integration, and maintaining consistent performance across platforms. Managing security, compliance, and cost optimization becomes more complex in a hybrid setup, requiring close collaboration with cybersecurity, application, and DevOps teams. Staying current with evolving technologies and orchestrating efficient workflows are essential for success in this role.

What is the role of Infrastructure Manager?

An Infrastructure Manager oversees an organization’s IT infrastructure, including networks, servers, data centers, and cloud services. They plan, implement, and maintain hardware and software systems, ensuring security, reliability, and efficiency, often coordinating with IT teams and managing budgets. Strong technical knowledge, project management skills, and certifications like ITIL or Cisco are typically required.

What is the difference between Infrastructure Manager vs Network Engineer?

AspectInfrastructure ManagerNetwork Engineer
CertificationsITIL, PMP, Cisco certificationsCCNA, CCNP, CompTIA Network+
Work EnvironmentOversees entire IT infrastructure, including servers, storage, and networksFocuses on designing, implementing, and maintaining network systems
Employer & Industry UsageCommon in large enterprises, data centers, and IT service providersFound in organizations needing network setup and support

While both roles involve IT infrastructure, the Infrastructure Manager oversees the entire infrastructure ecosystem, including networks, servers, and storage, whereas the Network Engineer specializes specifically in network design, implementation, and troubleshooting. The Infrastructure Manager has broader responsibilities, often managing teams and strategic planning, while the Network Engineer focuses on network-specific tasks.

What are the key skills and qualifications needed to thrive as an Infrastructure Manager, and why are they important?

To thrive as an Infrastructure Manager, you need expertise in IT infrastructure management, networking, and systems administration, often backed by a bachelor's degree in computer science or a related field. Familiarity with infrastructure-as-code tools, virtualization platforms, cloud services (like AWS or Azure), and certifications such as ITIL or Cisco are typically required. Strong leadership, problem-solving abilities, and effective communication skills help foster teamwork and drive strategic initiatives. These competencies ensure reliable, secure, and scalable technology operations critical to organizational success.

What are Infrastructure Managers?

Infrastructure Managers are professionals responsible for overseeing and maintaining an organization's IT infrastructure, including networks, servers, data centers, and related hardware and software systems. They ensure that all IT systems are running efficiently, securely, and reliably to support business operations. Their duties often include managing IT staff, planning infrastructure upgrades, coordinating with vendors, and developing disaster recovery strategies. Infrastructure Managers play a crucial role in minimizing downtime and optimizing the performance and security of technological assets.
More about Infrastructure Manager jobs
What are the most commonly searched types of Infrastructure jobs in San Ramon, CA? The most popular types of Infrastructure jobs in San Ramon, CA are:
What job categories do people searching Infrastructure Manager jobs in San Ramon, CA look for? The top searched job categories for Infrastructure Manager jobs in San Ramon, CA are:
What cities near San Ramon, CA are hiring for Infrastructure Manager jobs? Cities near San Ramon, CA with the most Infrastructure Manager job openings:
Infrastructure Manager jobs near you
Infographic showing various Infrastructure Manager job openings in San Ramon, CA as of July 2026, with employment types broken down into 94% Full Time, 3% Part Time, and 3% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $172,129 per year, or $82.8 per hour.
IT Infrastructure Manager

IT Infrastructure Manager

Lyell Immunopharma

South San Francisco, CA • On-site

Full-time

Re-posted 2 days ago

Job description

This role will be based out of South San Francisco, California, and reports to the Director, IT Infrastructure & Operations.
POSITION SUMMARY:
The individual in this role serves as the internal technical expert for Lyell's infrastructure, cloud, identity, and collaboration environments. This is a hands-on individual contributor role responsible for the configuration, implementation, and ongoing operation of these platforms in partnership with Lyell's managed service provider (MSP). Acting as the bridge between business requirements and infrastructure, this person translates stakeholder needs into scalable, compliant solutions and ensures Lyell operates reliable, validated infrastructure in a regulated life sciences environment.
KEY ROLE AND RESPONSIBILITIES:
  • Design and build infrastructure across cloud (AWS), on-premises, networking, identity, and collaboration platforms in line with best practices, industry standards, and Lyell's technology strategy.
  • Translate approved architectures and designs into detailed configurations and implementation plans; execute builds and changes, validate against requirements, and hand off steady-state operations to the MSP while retaining configuration and implementation ownership
  • Provide key technical input and feedback into architecture standards, infrastructure strategy, and roadmap planning led by IT leadership - drawing on hands-on knowledge of platform capabilities, constraints, and operational realities - and maintain up-to-date documentation of systems configuration and project status
  • Own the configuration, operation, and optimization of Lyell's AWS environment - implementing governance, cost management, and security controls per defined standards and identifying opportunities to optimize and maximize the value of Lyell's infrastructure investment.
  • Configure and maintain on-premises server and network systems, including VMware vSphere clusters, Windows Server, Active Directory, and network platforms (Juniper, Cisco Meraki, Palo Alto Networks) spanning routing, switching, firewall policy, and segmentation.
  • Ensure backup and disaster recovery integrity (e.g., Veeam), including monitoring backup health and resolving exceptions, and manage VPN, and telecommunications infrastructure.
  • Own the configuration, and governance of Okta, Microsoft 365, Zoom, and Slack as core infrastructure platforms, ensuring identity, access, and collaboration systems meet security, audit, and compliance requirements (e.g., access reviews, joiner/mover/leaver, audit logging).
  • Support lab infrastructure, including associated software and attached instrumentation.
  • Serve as primary day-to-day contact and technical authority over the MSP: define scope, review performance against SLAs, oversee implementation to ensure adherence to defined architecture, and ensure service delivery aligns with ITIL practices (incident, problem, change, and request management).
  • Act as the Tier 3 escalation point for the service desk, personally resolving complex or time-sensitive infrastructure incidents during business hours and providing guidance to service desk staff on end-user computing systems.
  • Participate in vendor evaluations, SOW reviews, supplier and hosted-solution oversight, and ongoing contract governance.
  • Own security tooling configuration per confirmed architecture (EDR, SIEM, and related platforms), and partner with the validation team on computer system validation (CSV) to ensure infrastructure designs support compliant, audit-ready operations and SOX and GxP audit activities.
  • Own the configuration, administration, and governance of Lyell's enterprise AI platforms - primarily Anthropic Claude - including user provisioning and access controls, workspace and policy configuration, integration with identity and collaboration systems, and usage monitoring, while partnering with compliance teams to ensure responsible, audit-ready use that meets the company's data-protection and regulatory requirements.

PREFERRED EDUCATION & EXPERIENCE:
  • BA/BS in an information technology field, or equivalent experience, with a minimum of 10 years in IT infrastructure, including 8+ years of hands-on solution architecture, technical design, and implementation across cloud, on-premises, and networking environments.
  • Demonstrated experience in a life sciences or biotech environment, including an understanding of GxP, validated systems, and regulated IT operations.
  • Deep AWS expertise - system engineering, cost governance, security, and operational best practices.
  • Extensive experience with Windows Server, VMware vSphere, and Active Directory across macOS, Windows, and Linux systems.
  • Hands-on administration and governance experience with Okta, Microsoft 365, Zoom, and Slack.
  • Strong network administration experience and fundamentals (routing, switching, firewall rules, segmentation), with hands-on experience on platforms such as Cisco Meraki and Palo Alto Networks.
  • Experience managing and monitoring system backups (e.g., Veeam), and managing VPN, telecommunications, and video conferencing solutions.
  • Experience with one or more scripting/automation languages (Python, PowerShell, Ruby, or equivalent) or leveraging AI or other workflow automation tools to automate repeatable work
  • Experience managing or overseeing MSP or third-party service delivery relationships, and serving as a Tier 3 escalation point for service desk or operations teams.
  • Familiarity administering or governing enterprise AI platforms (Anthropic Claude or equivalent), including user and workspace administration, access and policy controls, and responsible-use, data-protection, and compliance considerations.

KNOWLEDGE, SKILLS AND ABILITIES:
  • Prior experience working in the life sciences or biotech industry, with a working understanding of how IT operates in a regulated, GxP environment.
  • Comfortable working hands-on daily - designing and governing, but also personally executing and resolving incidents when speed or quality demands it.
  • Strong vendor management instincts - able to lead by influence rather than direct authority, push back, hold partners accountable, and escalate appropriately.
  • Excellent problem-solving, analytical, and decision-making skills, with the ability to navigate complex technical trade-offs and manage large projects.
  • Ability to produce clear system documentation and standards that others can execute against.
  • Excellent written and verbal communication skills; able to convey technical concepts to both technical and non-technical audiences and interact with leadership.
  • Ability to work independently and collaboratively across cross-functional teams, prioritize workflow, meet deadlines, and balance competing priorities.
  • Preferred: AWS certifications (Solutions Architect, Security Specialty, SysOps, or DevOps Engineer); experience with infrastructure-as-code tooling (Terraform, CloudFormation, or equivalent);

The salary range for this position is $175,000 to $195,000, annually, with the opportunity to earn an annual bonus. The salary range is an estimate, and the actual salary may vary based on Lyell's compensation practices and an applicant's qualifications and experience. Employees are also eligible to participate in Lyell's Equity Incentive Plan.
At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees. Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.
We've learned from experience that some of the best people don't always match our requirements perfectly - if you're interested and think you could fit, please don't hesitate to apply.

Apply