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Infrastructure Manager Jobs in Frederick, MD (NOW HIRING)

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Infrastructure Manager information

See Frederick, MD salary details

$80K

$153.1K

$196.9K

How much do infrastructure manager jobs pay per year?

As of Aug 9, 2026, the average yearly pay for infrastructure manager in Frederick, MD is $153,145.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,400.00 and $195,900.00 per year, depending on experience, location, and employer.

What does an infrastructure manager do?

An infrastructure manager works with an organization’s IT department to plan, design, and implement the technology ecosystem. Your responsibilities in this career include a range of other tasks to prepare and maintain the IT infrastructure. Duties can involve working with either hardware, software, or both, depending on the size of the business. You can also specialize in a particular aspect of the network. Your primary goal is to guarantee the security and integrity of the system. Some infrastructure manager positions also focus on budget, periodic reviews, or negotiations with vendors.

How much do infrastructure managers make?

In New York City, infrastructure managers typically earn between $100,000 and $150,000 annually, depending on experience, certifications, and the size of the organization. Salaries can vary based on industry sector and specific responsibilities, with senior roles often exceeding this range.

What are some common challenges an infrastructure manager faces when overseeing hybrid cloud environments?

Infrastructure Managers frequently encounter challenges in balancing on-premises and cloud-based resources, ensuring seamless integration, and maintaining consistent performance across platforms. Managing security, compliance, and cost optimization becomes more complex in a hybrid setup, requiring close collaboration with cybersecurity, application, and DevOps teams. Staying current with evolving technologies and orchestrating efficient workflows are essential for success in this role.

What is the difference between Infrastructure Manager vs Network Engineer?

AspectInfrastructure ManagerNetwork Engineer
CertificationsITIL, PMP, Cisco certificationsCCNA, CCNP, CompTIA Network+
Work EnvironmentOversees entire IT infrastructure, including servers, storage, and networksFocuses on designing, implementing, and maintaining network systems
Employer & Industry UsageCommon in large enterprises, data centers, and IT service providersFound in organizations needing network setup and support

While both roles involve IT infrastructure, the Infrastructure Manager oversees the entire infrastructure ecosystem, including networks, servers, and storage, whereas the Network Engineer specializes specifically in network design, implementation, and troubleshooting. The Infrastructure Manager has broader responsibilities, often managing teams and strategic planning, while the Network Engineer focuses on network-specific tasks.

What are the key skills and qualifications needed to thrive as an infrastructure manager, and why are they important?

To thrive as an Infrastructure Manager, you need expertise in IT infrastructure management, networking, and systems administration, often backed by a bachelor's degree in computer science or a related field. Familiarity with infrastructure-as-code tools, virtualization platforms, cloud services (like AWS or Azure), and certifications such as ITIL or Cisco are typically required. Strong leadership, problem-solving abilities, and effective communication skills help foster teamwork and drive strategic initiatives. These competencies ensure reliable, secure, and scalable technology operations critical to organizational success.

What is an infrastructure manager?

Infrastructure Managers are professionals responsible for overseeing and maintaining an organization's IT infrastructure, including networks, servers, data centers, and related hardware and software systems. They ensure that all IT systems are running efficiently, securely, and reliably to support business operations. Their duties often include managing IT staff, planning infrastructure upgrades, coordinating with vendors, and developing disaster recovery strategies. Infrastructure Managers play a crucial role in minimizing downtime and optimizing the performance and security of technological assets.
What are popular job titles related to Infrastructure Manager jobs in Frederick, MD? For Infrastructure Manager jobs in Frederick, MD, the most frequently searched job titles are:
What job categories do people searching Infrastructure Manager jobs in Frederick, MD look for? The top searched job categories for Infrastructure Manager jobs in Frederick, MD are:
What cities near Frederick, MD are hiring for Infrastructure Manager jobs? Cities near Frederick, MD with the most Infrastructure Manager job openings:
Infographic showing various Infrastructure Manager job openings in Frederick, MD as of August 2026, with employment types broken down into 83% Full Time, 16% Part Time, and 1% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $153,145 per year, or $73.6 per hour.

GMP IT Infrastructure and System (Sr) Engineer

AbelZeta Inc

Rockville, MD • On-site

$94K - $151K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 14 days ago


Job description

AbelZeta Inc. is a clinical-stage biopharmaceutical company focused on the development of novel immunotherapy products. AbelZeta operates a state-of-the-art facility in Rockville, Maryland with five GMP rooms and a QC laboratory in order to augment its global research and development capabilities and to support clinical development of multiple cell therapy platform technologies. We are on a rapid growth trajectory and have a highly energized and accomplished team driving to new frontiers of care for cancer and autoimmune disease patients.

We are seeking a GMP IT Infrastructure and System (Sr) Engineer to join our team. He or she will play a pivotal role in establishing and maintaining GMP Computer System, Data Integrity and Compliance and network security procedures. This role will be also responsible for managing the day-to-day IT operations activities.

Responsibilities and Duties:

  • Design, implement, and maintain GMP IT system infrastructure.
  • Manage day-to-day IT operations, partnering with vendors for support and ensure office internet/wifi reliability.
  • Set up and administration of lab instruments (including implementation of active directory, setting up user groups, user access, configuring systems, etc)
  • Identifies and implements software, hardware, and cloud solutions for data backup processes and other processes as needed
  • Build and maintain business continuity and disaster recovery strategies to minimize downtime and ensure rapid recovery of critical systems
  • Work with internal partners to understand strategy and business challenges to proactively recommend IT solutions and to deliver key programs and projects for the site.
  • Ensure compliance of company IT operations with the regulations and standards including but not limited to data security.
  • Provide IT support for computer system validation (CSV) to ensure data integrity per FDA regulation.
  • Works with Quality department to present change plans, change actions, and close assigned workflows
  • Assist with SOP generation as needed including, but not limited to, administration SOPs and access management procedures
  • IT suppliers management: overseeing the selection and onboarding of IT suppliers, monitoring performance metrics and cost, etc
  • IT fix assets management: tracking inventory of hardware, software, and network components and optimizing asset utilization to reduce costs and prevent redundancy, etc.
  • Other duties as assigned.

Qualifications and Requirements:

  • Bachelor’s degree in technology, engineering or computer science
  • At least 5 years of relevant and progressive experience driving process improvement and systems implementations and leading projects from design, development to implementation of IT solutions.
  • Familiarity with cell therapy laboratory instrument software, such as FACSLyric
  • Experience in biotech, pharma or life sciences manufacturing and lab with an understanding of what is required in a GMP environment is a must.
  • Expertise with implementing, configuring, and testing solutions.
  • Knowledge of 21 CFR Part 11, Annex 11, GAMP5, data integrity, and Computer systems Validation process
  • Experience in the life cycle management of computerized systems, including but not limited to: operation, change, upgrade, migration, file archiving, periodic review, retirement management, etc.
  • Experience in the internal and external audit support of computerized systems

Key Attributes

  • Self-starter with a go-getter attitude and the ability to proactively identify and solve problems.
  • Highly motivated with a strong sense of ownership and accountability.
  • Strong communication skills to effectively support both technical and non-technical users.
  • Empathetic and professional approach, with the ability to remain calm and supportive under pressure.
  • Team-oriented with the ability to collaborate across office and lab functions.

Why You Should Join AbelZeta

  • Join a high-growth and fast-paced organization.
  • Defined career path and annual performance review and feedback process.
  • Comprehensive Benefits Plan, including 100% company paid medical, dental, vision, life Insurance, short-term and long-term disability insurance, and more!
  • Competitive company 401k match.
  • Paid holidays, sick leave, and annual leave.

AbelZeta is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. AbelZeta validates right to work using E-Verify. Salary at AbelZeta is determined by various factors, including but not limited to location, the individual’s particular combination of education, knowledge, skills, competencies, and experience, as well as contract-specific affordability and organizational requirements. The estimate displayed represents the typical salary range for this position and is just one component of AbelZeta’s total compensation package for employees.