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Informatics Engineer Jobs (NOW HIRING)

Aptive

Health Informatics Program Manager

The ideal candidate will have experience leading software engineering, data and test teams and an interest in improving our healthcare system through data science applied across patient safety ...

STI

Clinical Informatics Analyst

Richmond, VA · On-site

Clinical Informatics Analyst Location: Richmond, VA Duration: 12+ Months IN PERSON IVS (No ... Provides technical leadership, estimates, technical training, process engineering and technical ...

Inovalon

Clinical Informatics & Ontology Lead

Collaborate closely with Data Engineering, Product, and Clinical teams to ensure that data ... Lead Informatics input into the migration of legacy reference tables to scalable terminology ...

Predicine

$150 - $200/hr

Software Engineer (Production Informatics) Full Time Professional Hayward, CA, US Software Engineer, Production Informatics About Predicine Predicine is a precision oncology company advancing the ...

Zifo

Head of Manufacturing Informatics

Define and execute the Manufacturing Informatics business strategy aligned with company growth ... , and Operations leaders. * Lead customer discovery sessions and understand manufacturing ...

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How much do informatics engineer jobs pay per year?

As of Sep 9, 2026, the average yearly pay for informatics engineer in the United States is $101,752.00, according to ZipRecruiter salary data. Most workers in this role earn between $84,000.00 and $116,500.00 per year, depending on experience, location, and employer.

What is an informatics engineer?

Informatics Engineers are professionals who design, develop, and maintain systems that manage and process information, often in fields like healthcare, business, or research. They combine expertise in computer science, information technology, and domain-specific knowledge to develop solutions that improve data management, analysis, and security. Their work often involves creating software tools, managing databases, and ensuring the efficient flow of information within organizations. Informatics Engineers play a crucial role in integrating technology with real-world processes to enhance decision-making and operational efficiency.

How does an informatics engineer typically collaborate with cross-functional teams in a healthcare setting?

Informatics Engineers often work closely with clinicians, IT professionals, and administrative staff to ensure that health information systems meet the needs of all stakeholders. They facilitate communication between technical and non-technical team members, translate clinical requirements into technical specifications, and support the integration of new technologies. This collaborative approach helps ensure that data workflows are efficient, secure, and aligned with healthcare regulations. Regular meetings, user training sessions, and feedback loops are common aspects of this teamwork.

What are the key skills and qualifications needed to thrive as an informatics engineer, and why are they important?

To thrive as an Informatics Engineer, you need a strong background in computer science, data management, and information systems, usually supported by a relevant degree and experience in software development. Familiarity with programming languages (such as Python or Java), database systems (like SQL), and health informatics standards or certifications (e.g., HL7, Certified Health Informatician) is commonly required. Strong analytical thinking, problem-solving, and effective communication skills help bridge the gap between technical teams and stakeholders. These skills ensure the efficient design, implementation, and maintenance of information systems that support organizational goals and data-driven decision-making.

What is the difference between Informatics Engineer vs Data Analyst?

AspectInformatics EngineerData Analyst
Required CredentialsBachelor's or higher in Computer Science, Information Systems, or related fieldsBachelor's in Statistics, Mathematics, or related fields; often with data analysis certifications
Work EnvironmentHealthcare, technology, or research settings focusing on information systemsBusiness, finance, marketing, or healthcare sectors analyzing data trends
Employer & Industry UsageDevelops and manages health or information systems in healthcare and tech industriesInterprets data to inform business decisions across various industries

Informatics Engineers and Data Analysts both work with data, but Informatics Engineers focus on developing and managing information systems, especially in healthcare and tech sectors. Data Analysts primarily interpret data to support business insights. While their skills overlap, their roles differ in scope and application.

Is an informatics engineer still in demand?

Informatics engineers are currently in demand due to the growing reliance on healthcare data management, electronic health records, and health IT systems. They often require skills in programming, data analysis, and knowledge of healthcare regulations, making them valuable in both healthcare and technology sectors.

What does an informatics engineer do?

An informatics engineer designs, develops, and maintains information systems and software solutions to manage and analyze data effectively. They often work with programming languages, databases, and data analysis tools to improve healthcare, business, or technology processes. Strong problem-solving skills and knowledge of data security are essential in this role.
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Informatics Engineer jobs near you
Infographic showing various Informatics Engineer job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 92% Full Time, 3% Part Time, and 4% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $101,752 per year, or $48.9 per hour.

Director, Research Informatics

South San Francisco, CA • On-site

Denali Therapeutics
Scientific Research and Development Services • 201 - 500 employees
Learn more about Denali Therapeuticsexternal

$204K - $265K/yr

Full-time

Medical, Retirement

Re-posted 14 hours ago

Key responsibilities

  • Owns the strategy, roadmap, and operational delivery of Research Informatics platforms and AI integration.

  • Leads and develops a team responsible for platform support, configuration, validation, and continuous improvement.

  • Partners with scientists and lab operations to translate requirements into scalable platform solutions.

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Research Informatics is responsible for the scientific data platforms and internal software that underpin the full research and development pipeline at Denali Therapeutics. This function owns the strategy, implementation, and ongoing support of the digital tools that enable scientists to register molecular entities and to track, analyze, and document associated experimental data across the full lifecycle, from early discovery through translational and development handoffs. These tools include Denali's Electronic Laboratory Notebook (ELN), the internal experiment data management platforms that underpin our scientific documentation, and the AI capabilities that unlock the full value of our data.
The Director of Research Informatics will lead this function, serving as the strategic and operational owner of our scientific data platforms, including Benchling, Dotmatics, and our internal software and AI tool integration. This individual will define the informatics roadmap, drive stakeholder alignment behind it, and build a high-caliber engineering team, while serving as a trusted technical partner to Discovery, enterprise IT, and other operational leadership. This is a hands-on leadership role: the Director will set technical direction and make software architecture and design-space decisions, not simply manage from a distance.
Key Accountabilities / Core Job Responsibilities
  • Owns the strategy, roadmap, and operational delivery of Research Informatics, including Benchling, Dotmatics, internal software systems, and AI integration.
  • Leads and grows a team responsible for platform support, configuration, validation, and continuous improvement across Discovery, Development, and Technical Operations.
  • Partners with scientists and lab operations leads to translate business and scientific requirements into scalable, well-engineered platform solutions.
  • Serves as subject matter expert on ELN capabilities and experiment data workflows, advising on platform selection and integration strategy.
  • Communicates platform strategy, status, and risk clearly to senior stakeholders, from group leaders to senior management.
  • Engages hands-on in configuration and platform build work, alongside strategic oversight.
  • Drives vendor relationships and manages platform migrations, escalations, and contract performance.
  • Explores and integrates next-generation, AI-driven experiment capture concepts, including passive documentation architectures that reduce manual interface dependency while preserving compliant, attributable records.
  • Owns roadmap prioritization and backlog decisions, balancing input from scientific, engineering, and IT stakeholders.
  • Leads direct report(s) through annual goal setting, growth planning, adherence to company policies, maintains training compliance, and provides ongoing feedback on growth, development, and areas of improvement.

Qualifications/Skills
  • Typically requires a Bachelor's degree in a technical field (computer science, data science, engineering, or related); advanced degree preferred.
  • Typically requires 10+ years building and delivering software solutions, including 7+ years in pharma, biotech, or life sciences supporting laboratory informatics or scientific platforms.
  • Typically requires 8+ years of people management experience, including building and growing engineering teams.
  • Hands-on expertise with scientific data platforms (e.g., Benchling, Dotmatics) and experience leading ELN/registry migrations preferred.
  • Experience partnering with enterprise IT on security, licensing, and infrastructure, and familiarity applying AI/ML workflows to biological or chemical data, preferred.

Salary Range: $204,000.00 to $265,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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