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Informatics Engineer Jobs in Boston, MA (NOW HIRING)

Software Engineer, UI

Boston, MA · On-site

$113K - $151K/yr

... Watershed Informatics is hiring an experienced UI Software Engineer to design and build powerful interface features for our genomic analysis and system management software. We're looking for ...

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Informatics Engineer information

See Boston, MA salary details

$42.4K

$110.5K

$149.4K

How much do informatics engineer jobs pay per year?

As of Aug 4, 2026, the average yearly pay for informatics engineer in Boston, MA is $110,544.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,300.00 and $126,600.00 per year, depending on experience, location, and employer.

How does an informatics engineer typically collaborate with cross-functional teams in a healthcare setting?

Informatics Engineers often work closely with clinicians, IT professionals, and administrative staff to ensure that health information systems meet the needs of all stakeholders. They facilitate communication between technical and non-technical team members, translate clinical requirements into technical specifications, and support the integration of new technologies. This collaborative approach helps ensure that data workflows are efficient, secure, and aligned with healthcare regulations. Regular meetings, user training sessions, and feedback loops are common aspects of this teamwork.

What is an informatics engineer?

Informatics Engineers are professionals who design, develop, and maintain systems that manage and process information, often in fields like healthcare, business, or research. They combine expertise in computer science, information technology, and domain-specific knowledge to develop solutions that improve data management, analysis, and security. Their work often involves creating software tools, managing databases, and ensuring the efficient flow of information within organizations. Informatics Engineers play a crucial role in integrating technology with real-world processes to enhance decision-making and operational efficiency.

What is the difference between Informatics Engineer vs Data Analyst?

AspectInformatics EngineerData Analyst
Required CredentialsBachelor's or higher in Computer Science, Information Systems, or related fieldsBachelor's in Statistics, Mathematics, or related fields; often with data analysis certifications
Work EnvironmentHealthcare, technology, or research settings focusing on information systemsBusiness, finance, marketing, or healthcare sectors analyzing data trends
Employer & Industry UsageDevelops and manages health or information systems in healthcare and tech industriesInterprets data to inform business decisions across various industries

Informatics Engineers and Data Analysts both work with data, but Informatics Engineers focus on developing and managing information systems, especially in healthcare and tech sectors. Data Analysts primarily interpret data to support business insights. While their skills overlap, their roles differ in scope and application.

What are the key skills and qualifications needed to thrive as an informatics engineer, and why are they important?

To thrive as an Informatics Engineer, you need a strong background in computer science, data management, and information systems, usually supported by a relevant degree and experience in software development. Familiarity with programming languages (such as Python or Java), database systems (like SQL), and health informatics standards or certifications (e.g., HL7, Certified Health Informatician) is commonly required. Strong analytical thinking, problem-solving, and effective communication skills help bridge the gap between technical teams and stakeholders. These skills ensure the efficient design, implementation, and maintenance of information systems that support organizational goals and data-driven decision-making.

Is an informatics engineer still in demand?

Informatics engineers are in high demand due to the increasing reliance on healthcare data management, electronic health records, and health IT systems. They often require skills in programming, data analysis, and knowledge of healthcare regulations, making them valuable in various healthcare and technology environments.
Infographic showing various Informatics Engineer job openings in Boston, MA as of July 2026, with employment types broken down into 92% Full Time, 4% Part Time, and 4% Contract. Highlights an 88% Physical, 5% Hybrid, and 7% Remote job distribution, with an average salary of $110,544 per year, or $53.1 per hour.

Clinical Informatics Specialist

InterSystems

Boston, MA

Other

Re-posted 29 days ago


Job description

We are seeking a highly skilled Clinical Informatics Specialist to play a pivotal role in the architecture and development of our canonical data model and transformation framework within the InterSystems ecosystem. Focus areas include data modeling, comprehensive documentation, and validating clinical workflows to ensure real-world clinical alignment.

In this role, you will act as the bridge between clinical experts and technical engineering teams.  You will be responsible for translating clinical needs into product requirements, defining complex data mappings, validating clinical logic, and ensuring our data models adhere to global HIT standards (FHIR, HL7v2, CDA, OMOP, etc.) while maintaining the highest standards of patient safety and data privacy.

Key Responsibilities
  1. Data Modeling & Transformation Strategy
  • Manage the governance of the canonical data model definition and maintenance processes in alignment with product strategy, ensuring it supports diverse clinical domains across the care continuum.
  • Design and document detailed logic for data transformations and mappings between various healthcare data standards (e.g., HL7v2, C-CDA, FHIR, X12, OMOP, openEHR).
  • Analyze emerging national and international Implementation Guides and regulatory standards, translating them into technical specifications for the engineering team to support future product capabilities.
  1. Clinical Terminology Management
  • Serve as the subject matter expert on standard terminologies and code sets, (e.g., SNOMED CT, LOINC, ICD-10, CPT/HCPCS, RxNorm).
  • Define concept maps and value sets to ensure semantic interoperability across the platform.
  • Troubleshoot terminology binding issues that arise during data ingestion or exchange.
  1. Clinical Requirements & Translation
  • Collaborate with clinical subject matter experts (SMEs) to gather requirements and translate "clinical intent" into precise technical specifications.
  • Author functional specifications that allow engineers to build robust interoperability pipelines within InterSystems product suite.
  • Act as a translator, explaining complex technical data constraints to clinicians and complex clinical workflows to engineers.
  1. Quality Assurance & Safety Validation
  • Validate data models and transformation logic to ensure they are clinically sound and accurately reflect the patient story.
  • Conduct clinical safety assessments on proposed data structures to identify and mitigate risks related to data loss, misinterpretation, or context stripping.
  • Ensure all data designs comply with privacy regulations (HIPAA, GDPR) and data governance policies.
Qualifications

Education & Experience

  • Clinical Background: Clinical degree (MD, DO, RN, PharmD, NP/PA) with active or previous licensure preferred; OR equivalent deep domain experience in Health Informatics.
  • Informatics Experience: 5+ years of experience in clinical informatics, data modeling, or interoperability analysis.
  • InterSystems Expertise: Proven experience working within InterSystems IRIS for Health or HealthShare environments is highly desired. Experience with other major integration engines combined with a willingness to learn InterSystems technology will also be considered.

Technical Skills & Knowledge

  • Standards: Deep mastery of HL7v2, C-CDA, and FHIR (resources, profiles, and implementation guides). Familiarity with OMOP CDM or openEHR archetypes is a strong plus.
  • Terminologies: Proficiency with LOINC, SNOMED CT, ICD-10, and RxNorm browsers and hierarchy structures.
  • Tools: Experience with mapping tools, SQL, and data modeling software.
  • Regulatory: Understanding of ONC certification rules (USCDI), TEFCA, and CMS interoperability rules.

Competencies

  • Translation: Ability to demystify technical jargon for clinicians and clinical workflows for developers.
  • Analytical Thinking: Strong capability to visualize data flows and identify edge cases in complex clinical scenarios.
  • Communication: Excellent written and verbal communication skills for creating documentation and specifications.
  • Leverage AI-assisted tools (e.g., large language models, copilots) to accelerate documentation, specification authoring, and data mapping workflows - while applying clinical judgment to validate outputs for accuracy and patient safety.
  • AI Fluency: Comfort using AI/LLM-based tools (e.g., coding assistants, document drafting copilots, terminology mapping aids) to improve productivity; ability to critically evaluate AI-generated outputs for clinical correctness and safety.

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.