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Immatics Jobs (NOW HIRING)

Senior CMC Program Manager

Houston, TX

$110K - $111K/yr

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Clinical Trial Manager

$130K - $150K/yr

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Senior CMC Program Manager

Houston, TX · On-site

$110K - $111K/yr

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Director, Medical Communications

Houston, TX · On-site +1

$220K - $270K/yr

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our ...

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Immatics information

What are some typical challenges faced by researchers working at Immatics in the field of immuno-oncology?

Researchers at Immatics often work on cutting-edge projects in immuno-oncology, which can present challenges such as navigating complex scientific problems and adapting to rapidly evolving technologies. Collaboration across multidisciplinary teams—including bioinformatics, clinical development, and laboratory groups—is essential, and effective communication is key to success. Additionally, balancing project timelines with the rigor required for high-quality research can be demanding but also highly rewarding for those passionate about making an impact in cancer therapy.

What is Immatics and what does the company do?

Immatics is a biotechnology company specializing in the development of immunotherapies for the treatment of cancer. The company focuses on discovering and developing T cell receptor (TCR)-based therapies that target cancer-specific antigens. Immatics combines its proprietary target discovery platform with advanced cell therapy and biologics technologies to create personalized cancer treatments. Their mission is to harness the power of the immune system to fight cancer more effectively and improve patient outcomes.

What is the difference between Immatics vs Clinical Research Associate?

AspectImmaticsClinical Research Associate
Required CredentialsBiotech or medical degree, relevant research experienceLife sciences degree, clinical research certification often preferred
Work EnvironmentBiotech or pharmaceutical company, research labsClinical trial sites, hospitals, research organizations
Employer & IndustryBiotech, immunotherapy, cancer researchPharmaceutical companies, contract research organizations
Common Search & ComparisonImmatics vs Clinical Research Associate

Immatics professionals focus on developing immunotherapy treatments in biotech settings, while Clinical Research Associates oversee clinical trials at research sites. Both roles require a background in life sciences, but Immatics roles are more research and development-oriented, whereas Clinical Research Associates are involved in trial management and compliance.

What are the key skills and qualifications needed to thrive as an employee at Immatics, a biotechnology company focused on cancer immunotherapies, and why are they important?

To thrive at Immatics, you generally need a strong background in biotechnology, molecular biology, or immunology, often with an advanced degree and relevant laboratory experience. Familiarity with tools such as flow cytometry, CRISPR gene editing, cell culture techniques, and data analysis software is highly valued, along with knowledge of regulatory standards. Strong teamwork, problem-solving, and effective communication skills help employees collaborate across multidisciplinary teams and adapt to a rapidly evolving research environment. These competencies are essential for advancing innovative cancer therapies and ensuring rigorous, high-quality scientific outcomes.
What cities are hiring for Immatics jobs? Cities with the most Immatics job openings:
What states have the most Immatics jobs? States with the most job openings for Immatics jobs include:
Infographic showing various Immatics job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Director, Facilities, Engineering, and Maintenance

Immatics NV

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 26 days ago


Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
  • Innovative Environment: Help to pioneer advancements in cancer immunotherapy.

  • Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

  • Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview:
Immatics is seeking an experienced Director of Facilities, Engineering & Maintenance to lead the infrastructure and engineering operations that power our next-generation cell therapy manufacturing environments. This role is instrumental in ensuring our highly specialized GMP facilities can support clinical manufacturing, operational scalability, and future commercial readiness for innovative cancer immunotherapies. The ideal candidate combines deep technical expertise in regulated biopharmaceutical operations with strong leadership, operational excellence, and the ability to scale complex infrastructure in a high-growth environment.
Reports to: Chief Operating Officer
Location: 13203 Murphy Road, Suite 100, Stafford, TX 77477
Basic Qualifications:
  • Bachelor's degree in Engineering (Mechanical, Electrical, Chemical, or related field)

  • 10+ years of experience in facilities engineering and maintenance within biotech, pharmaceutical, or other GMP-regulated environments

  • 5+ years of leadership experience managing engineering or facility operations teams

  • Demonstrated experience leading GMP facility projects (e.g., startup, expansion, or upgrades) and managing critical utilities and cleanroom operations

  • Proven experience ensuring compliance with GMP regulations, audits/inspections, and managing external contractors and capital projects

Preferred Qualifications:
  • Master's degree in Engineering, Facilities Management, or a related discipline

  • Experience in commercial-stage cGMP manufacturing environments

  • Experience in cell therapy, biologics, or advanced therapy medicinal products (ATMPs)

  • Certification in Project Management (PMP), Facilities Management (CFM), or similar

  • Experience with advanced systems (e.g., BMS/EMS, MES, LIMS, ERP, automation, digital maintenance platforms)

  • Advanced expertise in reliability engineering, risk management, and large-scale infrastructure planning in regulated environments

  • Demonstrated ability to lead complex, cross-functional initiatives in high-growth settings

In this role you will:
  • Lead facility engineering and maintenance strategy to support GMP manufacturing, R&D operations, and company growth

  • Oversee operation, maintenance, and lifecycle management of critical systems (e.g., HVAC, cleanrooms, utilities, automation)

  • Ensure facility compliance with regulatory standards and maintain audit and inspection readiness

  • Drive capital planning, facility expansion projects, and infrastructure scaling for commercial manufacturing

  • Partner cross-functionally on deviations, CAPAs, change controls, and validation activities

  • Manage external vendors, contractors, and budgets to deliver projects on time and within scope

  • Build and lead a high-performing engineering team while driving continuous improvement, safety, and operational excellence

Travel required: up to 10% travel required, domestically and internationally.
What do we offer?
At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics
Comprehensive Benefits:
  • Competitive rates for Health, Dental, and Vision Insurance

  • 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.

  • 12 company paid holidays

  • 7 days of sick time

  • 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars

  • 100% employer-paid short- and long-Term disability coverage

  • 401(k) with immediate eligibility and company match...

  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.

  • Partially paid parental leave for eligible employees.

  • Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity
We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.
Reasonable Accommodations
We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at PRIOR:
Work authorization/security clearance requirements
Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment
Affirmative Action/EEO statement
Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.