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Hplc Service Engineer Jobs in California (NOW HIRING)

Orion Group

Associate Scientist I

San Mateo, CA · On-site

$36 - $40/hr

... Services and our largest US client are seeking entry level scientists to support cell culture ... Basic: * BS in Biological Sciences or Chemical/Biochemical Engineering or related field with 0-3 ...

Shimadzu Scientific Instruments

$81K - $83K/yr

For Service, Technical Support, Marketing & Sales Roles: Additional compensation is available ... Chromatography (GC and HPLC) Mass Spectrometry (GCMS and LCMS Single Quadrupoles) Spectroscopy ...

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Hplc Service Engineer information

See California salary details

$19

$39

$65

How much do hplc service engineer jobs pay per hour?

As of Aug 23, 2026, the average hourly pay for hplc service engineer in California is $39.90, according to ZipRecruiter salary data. Most workers in this role earn between $31.78 and $45.10 per hour, depending on experience, location, and employer.

What is an HPLC Service Engineer?

HPLC Service Engineers are specialized professionals who install, maintain, troubleshoot, and repair High Performance Liquid Chromatography (HPLC) instruments used in laboratories. They ensure that these complex analytical machines operate properly, perform calibration, and provide technical support to laboratory staff. Their role is critical in pharmaceutical, chemical, and research labs where accurate and reliable analysis is essential. In addition to technical expertise, HPLC Service Engineers often train users on proper instrument operation and routine maintenance.

What skills and qualifications are needed to be an HPLC Service Engineer?

To thrive as an HPLC Service Engineer, you need a background in analytical chemistry or engineering, hands-on experience with HPLC systems, and often a relevant technical degree. Familiarity with chromatography software, diagnostic tools, and manufacturer certifications (such as from Agilent or Waters) is typically required. Strong problem-solving skills, customer service orientation, and effective communication are essential soft skills for this role. These competencies ensure accurate troubleshooting, minimal instrument downtime, and high customer satisfaction in laboratory environments.

What challenges do HPLC Service Engineers face and how can they be managed?

HPLC Service Engineers often encounter challenges such as diagnosing complex instrument malfunctions, managing tight service schedules, and adapting to rapidly changing technology. Effective troubleshooting requires a strong understanding of both hardware and software components, as well as clear communication with laboratory staff to accurately assess issues. Staying up-to-date with manufacturer training and maintaining a well-organized toolkit can greatly improve efficiency. Additionally, collaborating with other engineers or technical support teams is essential when addressing particularly difficult or unusual problems.

What is the difference between Hplc Service Engineer vs Laboratory Technician?

AspectHplc Service EngineerLaboratory Technician
CredentialsTechnical certifications, engineering or science degreeAssociate degree or diploma in laboratory sciences
Work EnvironmentField service, technical support, on-site repairsLaboratory setting, sample analysis, routine testing
Industry UsageManufacturers, biotech, pharmaceutical companiesResearch labs, clinical labs, educational institutions

The Hplc Service Engineer primarily focuses on maintaining and repairing HPLC systems, often working on-site at client locations. In contrast, Laboratory Technicians perform routine sample analysis within laboratory settings. While both roles require technical knowledge, the Hplc Service Engineer emphasizes equipment troubleshooting and servicing, whereas Laboratory Technicians focus on analytical testing and data collection.

What are popular job titles related to Hplc Service Engineer jobs in California?

For Hplc Service Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Hplc Service Engineer jobs in California look for?

The top searched job categories for Hplc Service Engineer jobs in California are:

Hplc Service Engineer jobs near you
Infographic showing various Hplc Service Engineer job openings in California as of August 2026, with employment types broken down into 85% Full Time, 5% Part Time, 2% Temporary, and 8% Contract. Highlights an 95% In-person, 2% Hybrid, and 3% Remote job distribution, with an average salary of $82,987 per year, or $39.9 per hour.

Process Engineer II, Life Sciences Industry (Direct Hire)

Marquee Staffing - Technical

Carlsbad, CA • On-site

$100K - $120K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 19 days ago

Job description

Process Engineer II

Carlsbad Area


This position reports to the Director of Technical Operations and will be responsible for providing expertise and guidance in the field of reagent formulation, filling and finishing activities for the Molecular Diagnostics & Life Sciences manufacturing segment of Argonaut Manufacturing Services. This individual will be hands-on and be directly involved with floor technicians to ensure proper techniques and guidelines are being followed.

This role is an on-site position Monday - Friday 8 hours/day (excluding lunch break). Overtime, weekends and holidays may be required. Flexible start time between 7:00 am - 9:00 am with a consistent schedule.

Duties and Responsibilities

  • Develop and validate methods associated with QC and Manufacturing processes
  • Design, specify and validate equipment and processes
  • Design and execute experiments to support process changes
  • Facilitate transition of new methodologies into manufacturing laboratory
  • Troubleshoot existing processes and provide guidance on potential enhancements
  • Perform IQ, OQ, and PQ for laboratory instruments
  • Respond to process and instrument failures to minimize downtime
  • Improve formulation processes and procedures
  • Review and support the transfer of client process steps for formulation/filling and improve, when possible
  • Responsible for development and implementation of production and analytical "In-process" controls for commercial manufacturing
  • Responsible for leading and executing transfer of NPIs from development to manufacturing shopfloor
  • Responsible for independently designing and executing experimental protocols, interpreting data from different sources/format and preparing scientific/operations development reports
  • Effective communication with all levels of organizational structure, through multiple departments
  • Responsible for leading quality investigations like deviations, CAPAs, NCMRs, OOS, OOT issues
  • Take initiative to develop and implement new processes to collect data around and analyze the health of production areas
  • Create and format technical documents like SOPs, master batch record and work instructions
  • Assist in defining technical requirements for new products
  • Responsible for identifying and on-boarding laboratory/floor equipment
  • Characterize and develop key metrics to drive efficiency and robustness improvements in product development
  • Collaborate with Development, Equipment engineering, Quality, Manufacturing, supply chain, and other departments as needed to address issues with and set appropriate specifications for manufactured products

Qualifications and Requirements

  • Bachelor's degree in Biology, Engineering, or Computer Science or related field and 4 or more years of experience in industrial setting
  • Knowledge of ISO 13485 Quality Management System and GMP
  • Must be meticulous and organized with excellent problem solving and analytical skills
  • Effective interpersonal and communication skills
  • Self-starter who can independently drive projects and day-to-day work tasks to completion while staying on schedule
  • Must work cross functionally with team
  • An understanding of LEAN practices and the use of continuous improvement tools like Kaizen, 5 why's, fishbone diagrams, DMAIC, poka yoke, value stream mapping
  • Understanding of FMEA and risk management
  • Experience in organic chemistry, chromatography (HPLC/UPLC, MPLC), NMR and other analytical techniques used in organic synthesis is preferred
  • Experience in large scale organic synthesis, clean room manufacturing is a plus
  • Familiarity with nucleoside/nucleotide chemistry, oligo synthesis is preferred
  • Familiarity with Statistical Process Control and DOE techniques is preferred
  • Experience in manufacturing support/sustaining and transferring products from R&D to production preferred
  • Experience in laboratory equipment identification and on-boarding is a plus
  • Experience with project management and associated organization tools is a plus