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Home Based Scientific Software Developer Jobs (NOW HIRING)

OpenEye Scientific

Within OpenEye's Cloud-based platform Orion, our team has already delivered to our clients ... home internet costs, public transportation reimbursement, and much more. We're doing work that ...

Cgg

Scientific Software Developer

Houston, TX · Hybrid

Master's degree or higher in Physics, Engineering, Mathematics, or Computer Science, or 5 years of ... Performance-based monthly bonus averaging at 10-15% at entry level ( contingent on financial ...

Cadence Design Systems Inc.

Within OpenEye's Cloud-based platform Orion, our team has already delivered to our clients ... home internet costs, public transportation reimbursement, and much more. We're doing work that ...

Viridien

Scientific Software Developer

Houston, TX · Hybrid

Master's degree or higher in Physics, Engineering, Mathematics, or Computer Science, or 5 years of ... Performance-based monthly bonus averaging at 10-15% at entry level ( contingent on financial ...

Cadence Design Systems Inc.

$101K - $188K/yr

Extend OpenEye's programming toolkits by developing and implementing new and useful scientific and ... Please note that the salary range is a guideline and compensation may vary based on factors such as ...

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Home Based Scientific Software Developer information

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$83.5K

$102.5K

$135.5K

How much do home based scientific software developer jobs pay per year?

As of Jun 21, 2026, the average yearly pay for home based scientific software developer in the United States is $102,500.00, according to ZipRecruiter salary data. Most workers in this role earn between $90,000.00 and $115,000.00 per year, depending on experience, location, and employer.

What is the difference between Home Based Scientific Software Developer vs Scientific Software Engineer?

AspectHome Based Scientific Software DeveloperScientific Software Engineer
CredentialsBachelor's or Master's in Computer Science, Physics, or related fieldsBachelor's or Master's in Computer Science, Engineering, or related fields
Work EnvironmentRemote, home-based setupTypically office or lab environment, but may include remote work
Industry UsageResearch institutions, academia, biotech, environmental agenciesResearch labs, industry R&D, government agencies
Common Search/ComparisonYesYes

The main difference is that a Home Based Scientific Software Developer primarily works remotely on scientific software projects, often in academia or research settings, while a Scientific Software Engineer may work in more traditional office or lab environments within industry or government. Both roles require similar educational backgrounds and skills, but their work settings and typical employers differ.

What are some common challenges for home-based scientific software developers and how can they be addressed?

Home-based scientific software developers often face challenges such as maintaining clear communication with research teams, managing time effectively without in-person supervision, and ensuring access to necessary computing resources. Overcoming these challenges typically involves using collaborative tools like version control systems (e.g., Git), regular video meetings, and cloud-based platforms for code sharing and testing. Establishing a structured daily routine and staying updated with scientific advancements also helps developers stay productive and connected with their team.

What are the key skills and qualifications needed to thrive as a Home Based Scientific Software Developer, and why are they important?

A Home Based Scientific Software Developer needs strong programming skills (often in Python, C++, or MATLAB), a solid background in mathematics or a scientific discipline, and typically at least a bachelor's degree in computer science, engineering, or a related field. Familiarity with scientific computing libraries, version control systems like Git, and experience with cloud-based or distributed computing platforms are commonly required. Excellent problem-solving abilities, self-motivation, and effective remote communication are vital soft skills for success in a home-based setting. These competencies ensure the developer can build reliable, efficient scientific software, collaborate virtually with researchers, and deliver solutions that advance scientific discovery.

What is a Home Based Scientific Software Developer?

A Home Based Scientific Software Developer is a professional who designs, develops, and maintains software tools used for scientific research and analysis, while working remotely from home. They often collaborate with scientists, researchers, and engineers to create programs that process data, simulate experiments, or visualize scientific phenomena. This role requires strong programming skills, knowledge of scientific principles, and the ability to work independently using remote communication tools. Home based roles offer flexibility, allowing developers to contribute to research projects and software solutions from anywhere. These professionals are essential in fields like bioinformatics, physics, chemistry, and environmental science.
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What cities are hiring for Home Based Scientific Software Developer jobs? Cities with the most Home Based Scientific Software Developer job openings:
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Home Based Scientific Software Developer jobs near you
Infographic showing various Home Based Scientific Software Developer job openings in the United States as of June 2026, with employment types broken down into 60% Full Time, 25% Part Time, and 15% Contract. Highlights an 87% Physical, 1% Hybrid, and 12% Remote job distribution, with an average salary of $102,500 per year, or $49.3 per hour.
Scientific Software Developer - Affinity

Scientific Software Developer - Affinity

OpenEye Scientific

Santa Fe, NM • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 21 days ago

Job description

Over the last eight years, OpenEye Scientific has developed the field's most advanced large-scale compute platform, Orion, built on Amazon Web Services. In this position, you will be working at the cutting edge of cloud computing, C++/Python development, and advanced MD simulation techniques. Your work will have the potential to make a major impact in drug discovery, and will be available to many pharmaceutical and biotech companies.
OpenEye, Cadence Molecular Sciences, an industry leader in computational molecular design, uses a scientific approach to deliver rapid, robust, and scalable software, toolkits, and technology & design services for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors and fragrances. We are passionate about science and about taking care of our team members, with leaders supporting your development and recognizing your contributions by providing an unmatched total compensation package in a collaborative, caring, energetic and fun work environment.
The Affinity Group at OpenEye seeks to hire a scientific software developer to join a growing team delivering Molecular Dynamics (MD) based solutions for predicting protein-ligand binding affinities. Within OpenEye's Cloud-based platform Orion, our team has already delivered to our clients massively parallel Relative Binding Free Energy (RBFE) tools capable of calculating affinities on dozens of ligands in only hours, using hundreds of GPUs. We are also developing faster, higher throughput MD-based prescreening approaches to use upstream of the heavier free energy methods. With your experience in MD and programming, you will help us to extend our capabilities in this area, making both our science and our tools better: more robust, more accurate, and more efficient. The work you do will have a high impact, contributing to the science of many organizations, both industry-based and academic. In this you will be collaborating with experienced scientific developers with expertise in small molecule drug discovery and long track records of delivering useful solutions and liaising with academic collaborators in the simulations community.
Please include a cover letter.
What you should have:
  • PhD. with PostDoc in an area related to structure-based ligand design methods.
  • 3 or more years of experience in scientific programming with Python.
  • 3 or more years of experience with Molecular Dynamics including Free Energy Calculations.
  • Experience in computational chemistry methods development, implementation, and validation
  • Team-oriented with good communication skills and professional scientific presentation skills.
  • Ability and desire to learn new ideas and adapt to new development practices

The following are a PLUS, but not required:
  • Knowledge & skill in programming and professional software development practices & tools
  • Experience with a multi platform and/or distributed computing environment including cloud computing.
  • Knowledge of chemistry and/or drug discovery & development

Benefits:
OpenEye is passionate about the welfare of its employees and offers competitive benefits that include medical, dental, vision, flexible working schedule, 401k retirement plans, paid vacation, paid sick leave, home internet costs, public transportation reimbursement, and much more.
We're doing work that matters. Help us solve what others can't.

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