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Histocompatibility Technologist Jobs (NOW HIRING)

We are currently looking for a Histocompatibility Technologist to join our team. This is an exciting opportunity to join a company with a reputation for exceptional service and patient care. POSITION ...

We are currently looking for a Histocompatibility Technologist to join our team. This is an exciting opportunity to join a company with a reputation for exceptional service and patient care. POSITION ...

The Histocompatibility Technologist provide accurate and timely clinical diagnostic information to healthcare professionals to ensure high quality patient care and customer service. Performs testing ...

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Histocompatibility Technologist information

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How much do histocompatibility technologist jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for histocompatibility technologist in the United States is $33.01, according to ZipRecruiter salary data. Most workers in this role earn between $22.36 and $40.14 per hour, depending on experience, location, and employer.

What is a histocompatibility technologist?

A Histocompatibility Technologist performs specialized laboratory tests to assess tissue compatibility for organ and bone marrow transplantation. They analyze blood and tissue samples to determine human leukocyte antigen (HLA) matching, detect antibodies, and identify potential transplant rejection risks. Their work ensures successful organ transplants by minimizing immune system complications. These professionals typically work in transplant laboratories, hospitals, or research institutions. Strong attention to detail and expertise in molecular biology, immunology, and laboratory techniques are essential for this role.

What are the key skills and qualifications needed to thrive as a histocompatibility technologist?

To thrive as a Histocompatibility Technologist, you need a strong background in clinical laboratory science, immunology, and molecular biology, often supported by a relevant bachelor's degree and medical laboratory technician certification. Experience with specialized laboratory equipment such as flow cytometers, PCR instruments, and data management systems like HLA typing software is crucial. Attention to detail, strong analytical thinking, and effective communication are important soft skills for interpreting results and collaborating with clinical teams. These skills ensure accurate compatibility testing, which is vital for successful organ and bone marrow transplantation outcomes.

Is histocompatibility technologist a good career?

A histocompatibility technologist plays a vital role in tissue typing and transplant compatibility testing, requiring knowledge of immunology and laboratory techniques. The profession offers stable employment opportunities, often with certification requirements, and can lead to advancement in clinical laboratory settings. It is considered a reliable career choice for those interested in healthcare and laboratory science.

What are the typical daily responsibilities of a histocompatibility technologist?

As a Histocompatibility Technologist, your daily responsibilities include performing and analyzing tissue typing and antibody screening tests, preparing specimens, operating complex laboratory instrumentation, and accurately documenting and reporting results. You will collaborate closely with transplant coordinators, physicians, and other laboratory staff to ensure timely and reliable compatibility results for organ and stem cell transplantation. Additionally, you may participate in troubleshooting equipment issues and maintaining quality control standards. This role requires a commitment to precision and effective teamwork to support critical patient care decisions.

What does a histocompatibility technologist do?

A histocompatibility technologist performs laboratory tests to determine tissue compatibility between donors and recipients, primarily for organ and bone marrow transplants. They analyze blood and tissue samples using techniques like crossmatching and HLA typing, often working with specialized equipment and adhering to strict quality standards. Certification and attention to detail are important in this role.
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Infographic showing various Histocompatibility Technologist job openings in the United States as of August 2026, with employment types broken down into 96% Full Time, and 4% Part Time. Highlights an 100% In-person job distribution, with an average salary of $68,664 per year, or $33 per hour.

Histocompatibility Technologist

UnityPoint Health

Des Moines, IA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 23 days ago


UnityPoint Health rating

7.3

Company rating: 7.3 out of 10

Based on 361 frontline employees who took The Breakroom Quiz

270th of 887 rated healthcare providers


Job description

$5,000 Sign on Bonus!

The Histocompatibility Technologist provide accurate and timely clinical diagnostic information to healthcare professionals to ensure high quality patient care and customer service. Performs testing for both living and deceased donor transplantation including human leukocyte antigen (HLA) testing, antibody screening, and flow cytometric crossmatches. Rotates into call schedules as determined by department. 


At UnityPoint Health, you matter. We’re proud to be recognized as a Top Place to Work in Healthcare by Becker's Healthcare several years in a row for our commitment to our team members.


Our competitive Total Rewards program offers benefits options focused on your needs and priorities, no matter what life stage you’re in.Here are just a few:


• Expect paid time off, parental leave, 401K matching and an employee recognition program.
• Dental, health and vision insurance, paid holidays, short and long-term disability and more. We even offer pet insurance for your four-legged family members.
• Early access to earned wages with Daily Pay, tuition reimbursement to help further your career and adoption assistance to help you grow your family.

With a collective goal to champion a culture of belonging where everyone feels valued and respected, we honor the ways people are unique and embrace what brings us together.

And, we believe equipping you with support and development opportunities is a vital part of delivering an exceptional employment experience.

Join our team of experts and make a difference with UnityPoint Health.


Performs immunological work-ups within the required time of current organ preservation methods.

· Performs crossmatches between recipients and donors (live or deceased) identified by the United Network for Organ Sharing (UNOS) and the Iowa Donor Network. Responsible for extent of crossmatching and selection of appropriate sera.

· Performs complex laboratory procedures utilized for the diagnosis and treatment of disease as appropriate for patient age to include neonates, infants, children, adolescents, adults, and geriatric adults; recognizes deviation from expected results; analyzes and corrects problems using scientific principles.

· Screens potential recipients for anti-HLA antibody determination.

Training  

  • Instructs, trains, and evaluates students and new employees. 
  • Quality 

    • Documents and maintains quality control (QC), proficiency testing, quality assurance, and other records to meet regulatory requirements. 
    • Critical Thinking 

      • Performs, evaluates, and documents advanced troubleshooting and problem-solving activities; liaisons with clients and nursing personnel, and interprets data for appropriate health professionals. 

Previous Histocompatibility Laboratory experience preferred. 

Bachelor’s Degree in Science must be obtained which is sufficient to allow certification under one of the Medical Technologist (MT)/Medical Laboratory Scientist (MLS) or Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS)  Certifying Agencies’ examination routes.  Must meet Clinical Laboratory Improvement Amendments (CLIA) requirements to perform highly complex testing.  

Certifying Agencies include but are not limited to the American Society for Clinical Pathology (ASCP),  Board of Certification (BOC), American Medical Technologist (AMT) Certification, American Association of Bioanalysts (AAB) Board of Registry (ABOR) and American Board of Histocompatibility and Immunogenetics (ABHI). As long as these are met, any exam may be taken. Additionally, any regulatory agency personnel standards, which are applicable to the position, must be met.     

Experience in clinical laboratory disciplines sufficient to allow certification under one of the Medical Technologist (MT)/Medical Laboratory Scientist (MLS) or a Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS).  Certifying Agencies’ examination routes is required.  One year of experience with PRA and DSA testing.  

Technician Certification Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS) Technologist/Scientist (MT/MLS)  

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About UnityPoint Health

Sourced by ZipRecruiter

At UnityPoint Health, we provide care in nine regions throughout Illinois, Iowa, and Wisconsin. As the nation's fourth largest nondenominational health system in America, UnityPoint Health keeps people at the center of all we do. We are looking for dynamic and talented individuals to join our team. You'll find opportunities for every sized dream.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

West Des Moines, IA, US

Year founded

1995