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Histocompatibility Technologist Jobs (NOW HIRING)

University Health

Histocompatibility Tech

San Antonio, TX · On-site

$21 - $37/hr

We are currently looking for a Histocompatibility Technologist to join our team. This is an exciting opportunity to join a company with a reputation for exceptional service and patient care. POSITION ...

University Health

Histocompatibility Tech

San Antonio, TX · On-site

$21 - $37/hr

We are currently looking for a Histocompatibility Technologist to join our team. This is an exciting opportunity to join a company with a reputation for exceptional service and patient care. POSITION ...

The University of Toledo

Lab Sr Tech

Toledo, OH · On-site

$32.83 - $39.68/hr

... Histocompatibility Technologist (CHT) or Clinical Histocompatibility Specialist (CHS) certification by the American College of Histocompatibility and Immunogenetics (ACHI) • Ability to multi-task ...

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How much do histocompatibility technologist jobs pay per hour?

As of Jun 14, 2026, the average hourly pay for histocompatibility technologist in the United States is $33.01, according to ZipRecruiter salary data. Most workers in this role earn between $22.36 and $40.14 per hour, depending on experience, location, and employer.

What is a Histocompatibility Technologist job?

A Histocompatibility Technologist performs specialized laboratory tests to assess tissue compatibility for organ and bone marrow transplantation. They analyze blood and tissue samples to determine human leukocyte antigen (HLA) matching, detect antibodies, and identify potential transplant rejection risks. Their work ensures successful organ transplants by minimizing immune system complications. These professionals typically work in transplant laboratories, hospitals, or research institutions. Strong attention to detail and expertise in molecular biology, immunology, and laboratory techniques are essential for this role.

What are the key skills and qualifications needed to thrive in the Histocompatibility Technologist position, and why are they important?

To thrive as a Histocompatibility Technologist, you need a strong background in clinical laboratory science, immunology, and molecular biology, often supported by a relevant bachelor's degree and medical laboratory technician certification. Experience with specialized laboratory equipment such as flow cytometers, PCR instruments, and data management systems like HLA typing software is crucial. Attention to detail, strong analytical thinking, and effective communication are important soft skills for interpreting results and collaborating with clinical teams. These skills ensure accurate compatibility testing, which is vital for successful organ and bone marrow transplantation outcomes.

What is a histocompatibility technologist?

A histocompatibility technologist is a laboratory professional who performs tests to determine tissue compatibility for organ and bone marrow transplants. They analyze human leukocyte antigen (HLA) samples using specialized techniques and equipment, often working in clinical or research laboratories. Certification and knowledge of immunology, laboratory procedures, and quality control are typically required for this role.

What jobs can I get with SLT?

A Histocompatibility Technologist with SLT (Serology and Lymphocyte Typing) training can pursue roles in tissue typing laboratories, transplant centers, and research institutions. These positions involve performing HLA typing, crossmatching, and immunogenetic testing to support organ and tissue transplantation processes. Certification and familiarity with laboratory techniques and equipment are often required for these roles.

What lab techs make the most money?

Among laboratory technologists, histocompatibility technologists tend to earn higher salaries due to specialized skills in tissue typing and transplant compatibility testing. Salaries for these roles are influenced by experience, certifications, and work setting, with those in hospital or research environments typically earning more. Overall, advanced certifications and years of experience can significantly increase earning potential for lab technicians in specialized fields.

How do you become a histocompatibility technologist?

To become a histocompatibility technologist, one typically needs a bachelor's degree in biology, immunology, or a related field, along with specialized training in histocompatibility testing. Certification from organizations such as the American Society for Histocompatibility and Immunogenetics (ASHI) is often required or preferred, and on-the-job training is common in clinical laboratory settings.

What are the typical daily responsibilities of a Histocompatibility Technologist?

As a Histocompatibility Technologist, your daily responsibilities include performing and analyzing tissue typing and antibody screening tests, preparing specimens, operating complex laboratory instrumentation, and accurately documenting and reporting results. You will collaborate closely with transplant coordinators, physicians, and other laboratory staff to ensure timely and reliable compatibility results for organ and stem cell transplantation. Additionally, you may participate in troubleshooting equipment issues and maintaining quality control standards. This role requires a commitment to precision and effective teamwork to support critical patient care decisions.

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Histocompatibility Technologist jobs near you
Infographic showing various Histocompatibility Technologist job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $68,664 per year, or $33 per hour.
Histocompatibility Technologist

Histocompatibility Technologist

UnityPoint Health

Des Moines, IA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 20 days ago

UnityPoint Health rating

7.3

Company rating: 7.3 out of 10

Based on 354 frontline employees who took The Breakroom Quiz

294th of 872 rated healthcare providers

Job description

Overview
$5,000 Sign on Bonus!
The Histocompatibility Technologist provide accurate and timely clinical diagnostic information to healthcare professionals to ensure high quality patient care and customer service Performs testing for both living and deceased donor transplantation including human leukocyte antigen (HLA) testing, antibody screening, and flow cytometric crossmatches. Rotates into call schedules as determined by department.
Why UnityPoint Health?
At UnityPoint Health, you matter. We're proud to be recognized as a Top Place to Work in Healthcare by Becker's Healthcare several years in a row for our commitment to our team members.
Our competitive Total Rewards program offers benefits options focused on your needs and priorities, no matter what life stage you're in. Here are just a few:
• Expect paid time off, parental leave, 401K matching and an employee recognition program.
• Dental, health and vision insurance, paid holidays, short and long-term disability and more. We even offer pet insurance for your four-legged family members.
• Early access to earned wages with Daily Pay, tuition reimbursement to help further your career and adoption assistance to help you grow your family.
With a collective goal to champion a culture of belonging where everyone feels valued and respected, we honor the ways people are unique and embrace what brings us together.
And, we believe equipping you with support and development opportunities is a vital part of delivering an exceptional employment experience.
Join our team of experts and make a difference with UnityPoint Health.
Responsibilities
Performs immunological work-ups within the required time of current organ preservation methods.
• Performs crossmatches between recipients and donors (live or deceased) identified by the United Network for Organ Sharing (UNOS) and the Iowa Donor Network. Responsible for extent of crossmatching and selection of appropriate sera.
• Performs complex laboratory procedures utilized for the diagnosis and treatment of disease as appropriate for patient age to include neonates, infants, children, adolescents, adults, and geriatric adults; recognizes deviation from expected results; analyzes and corrects problems using scientific principles.
• Screens potential recipients for anti-HLA antibody determination.
Training
  • Instructs, trains, and evaluates students and new employees.
  • Quality
    • Documents and maintains quality control (QC), proficiency testing, quality assurance, and other records to meet regulatory requirements.
    • Critical Thinking
      • Performs, evaluates, and documents advanced troubleshooting and problem-solving activities; liaisons with clients and nursing personnel, and interprets data for appropriate health professionals.

Qualifications
Previous Histocompatibility Laboratory experience preferred.
Bachelor's Degree in Science must be obtained which is sufficient to allow certification under one of the Medical Technologist (MT)/Medical Laboratory Scientist (MLS) or Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS) Certifying Agencies' examination routes. Must meet Clinical Laboratory Improvement Amendments (CLIA) requirements to perform highly complex testing.
Certifying Agencies include but are not limited to the American Society for Clinical Pathology (ASCP), Board of Certification (BOC), American Medical Technologist (AMT) Certification, American Association of Bioanalysts (AAB) Board of Registry (ABOR) and American Board of Histocompatibility and Immunogenetics (ABHI). As long as these are met, any exam may be taken. Additionally, any regulatory agency personnel standards, which are applicable to the position, must be met.
Experience in clinical laboratory disciplines sufficient to allow certification under one of the Medical Technologist (MT)/Medical Laboratory Scientist (MLS) or a Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS). Certifying Agencies' examination routes is required. One year of experience with PRA and DSA testing.
Technician Certification Histocompatibility Technologist (CHT)/Histocompatibility Specialist (CHS) Technologist/Scientist (MT/MLS)

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About UnityPoint Health

Sourced by ZipRecruiter

At UnityPoint Health, we provide care in nine regions throughout Illinois, Iowa, and Wisconsin. As the nation's fourth largest nondenominational health system in America, UnityPoint Health keeps people at the center of all we do. We are looking for dynamic and talented individuals to join our team. You'll find opportunities for every sized dream.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

West Des Moines, IA, US

Year founded

1995

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