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High Throughput Screening Jobs (NOW HIRING)

The ideal candidate is experienced in molecular biology, biochemistry, mammalian cell culture, and high-throughput screening methods. You will work both collaboratively and independently with ...

Biology Lab Technician - Automation

Austin, TX · On-site

$18.75 - $25/hr

We work across protein engineering, synthetic biology, and high-throughput screening to create biological tools that operate in extreme environments and at field scale. Then we do the hard part ...

Biology Lab Technician - Automation

Austin, TX · On-site

$18.75 - $25/hr

We work across protein engineering, synthetic biology, and high-throughput screening to create biological tools that operate in extreme environments and at field scale. Then we do the hard part ...

Position Manifold Bio is seeking a scientist to build and own a high-throughput, automated cell-free display platform for screening computationally designed protein binder libraries against hundreds ...

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High Throughput Screening information

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$14

$23

$34

How much do high throughput screening jobs pay per hour?

As of Jun 7, 2026, the average hourly pay for high throughput screening in the United States is $23.94, according to ZipRecruiter salary data. Most workers in this role earn between $18.99 and $28.37 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a High Throughput Screening (HTS) Scientist, and why are they important?

To thrive as a High Throughput Screening Scientist, you need a solid background in biology or chemistry, experience with assay development, and often a relevant advanced degree. Familiarity with automated liquid handling systems, data analysis software, and laboratory information management systems (LIMS) is essential. Strong problem-solving, attention to detail, and effective teamwork are standout soft skills in this role. These skills are critical for efficiently identifying potential drug candidates and ensuring accurate, reproducible results in a fast-paced research environment.

What is high throughput screening in drug discovery?

High throughput screening (HTS) is a laboratory technique used in drug discovery to quickly test thousands to millions of chemical compounds for activity against a biological target. By using automated equipment, robotics, and data analysis tools, researchers can identify potential drug candidates more efficiently than traditional methods. HTS accelerates the early stages of drug development by providing rapid, large-scale screening, which helps scientists prioritize compounds for further study. This approach is widely used in pharmaceutical research and biotechnology companies.

What are some common challenges faced in a High Throughput Screening (HTS) role, and how can they be addressed?

One common challenge in High Throughput Screening is managing large volumes of data generated from automated assays, which requires strong data analysis skills and attention to detail. Another challenge is ensuring assay reliability and minimizing variability, which often involves close collaboration with assay development scientists and automation engineers. Effective communication within multidisciplinary teams is essential to troubleshoot issues quickly and adapt protocols as needed. Staying organized and proactively addressing equipment maintenance can also help minimize downtime and improve screening efficiency.

What is the difference between High Throughput Screening vs Laboratory Technician?

AspectHigh Throughput ScreeningLaboratory Technician
Required credentialsBachelor's degree in biology, chemistry, or related field; experience with automationAssociate's or bachelor's degree; basic lab skills
Work environmentResearch labs focused on drug discovery and screeningGeneral laboratory settings across various industries
Employer and industry usagePharmaceutical, biotech, research institutionsHospitals, research labs, manufacturing plants
Common search and comparison intentUnderstanding roles in drug discovery and screening processesGeneral lab work and technical support roles

High Throughput Screening specialists focus on automating and conducting large-scale testing of compounds to identify potential drug candidates, requiring specialized skills and equipment. Laboratory Technicians perform routine lab tasks across various settings, supporting research and testing processes. While both roles work in laboratory environments, their responsibilities, skills, and industry focus differ significantly.

More about High Throughput Screening jobs
What cities are hiring for High Throughput Screening jobs? Cities with the most High Throughput Screening job openings:
What states have the most High Throughput Screening jobs? States with the most job openings for High Throughput Screening jobs include:
Infographic showing various High Throughput Screening job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 88% In-person, and 12% Hybrid job distribution, with an average salary of $49,790 per year, or $23.9 per hour.

Senior Scientist, Analytical Chemistry

Lila Sciences

Cambridge, MA • On-site

Full-time

Medical, Dental, Vision, Life

Posted 13 days ago


Job description

Your Impact at LILA
The Senior Scientist, Analytical Chemistry will develop and deploy advanced analytical and characterization strategies to support Discovery Chemistry efforts across Lila's platform, with a focus on enabling the rapid design, synthesis, screening, and optimization of small molecules and related molecular matter. This scientist will play a key role in generating high-quality, information-rich experimental data that informs chemistry decisions and accelerates platform learning.
Working closely with Discovery Chemistry, automation, AI/computational, and screening teams, this role will establish and scale multimodal characterization workflows that go beyond traditional analytical chemistry approaches. The Senior Scientist will help build an integrated analytical capability spanning compound characterization, reaction monitoring, molecular profiling, and high-throughput data generation to support fast and iterative design-make-test-analyze cycles.
This role will be critical to shaping Lila's next-generation discovery engine by combining deep expertise in analytical chemistry with high-throughput experimentation, multimodal data generation, AI-enabled workflows.
What You'll Be Building
  • Develop, optimize, and implement analytical and multimodal characterization workflows to support Discovery Chemistry programs and molecular discovery campaigns.
  • Support the design, synthesis, screening, and optimization of small molecules by delivering rapid, reliable, and information-rich analytical data.
  • Lead analytical method development for compound identification, purity assessment, impurity profiling, reaction monitoring, and molecular characterization using techniques such as liquid chromatography, mass spectroscopy, NMR, and complementary orthogonal methods.
  • Build characterization strategies that extend beyond traditional analytical methods, incorporating multimodal measurements that provide deeper insight into molecular identity, reaction outcomes, physicochemical properties, and structure-function relationships.
  • Partner closely with Discovery Chemistry and screening teams to support high-throughput screening and high-throughput experimentation workflows, including rapid sample analysis, reaction triage, and compound profiling.
  • Collaborate with automation and platform teams to integrate analytical instrumentation and data pipelines into robotics-enabled and scalable discovery workflows.
  • Work closely with AI and computational teams to ensure analytical datasets are structured, interoperable, and useful for model development, closed-loop learning, and iterative molecule design.
  • Establish robust workflows for reaction monitoring, in-process analytics, final compound quality assessment, and characterization of complex mixtures or intermediates.
  • Troubleshoot analytical and characterization challenges related to sample preparation, instrumentation, method robustness, data interpretation, and workflow integration.
  • Contribute to the development of platform-level capabilities for data-rich molecular discovery, including scalable characterization pipelines, method standardization, and best practices for analytical rigor.

What You'll Need to Succeed
  • PhD in Analytical Chemistry, Organic Chemistry, Pharmaceutical Sciences, Chemical Biology, or a related scientific discipline with 5-8+ years of relevant industry or high-performance research experience.
  • Deep expertise in analytical chemistry and molecular characterization in support of chemistry-driven discovery efforts.
  • Strong hands-on experience with key analytical techniques for small molecule analysis.
  • Demonstrated experience developing analytical methods for compound characterization, reaction monitoring, impurity analysis, and purity assessment.
  • Experience supporting Discovery Chemistry, medicinal chemistry, synthetic chemistry, or other molecule-focused R&D environments.
  • Strong understanding of how analytical data informs compound progression, screening decisions, reaction optimization, and molecular design.
  • Experience working with or supporting high-throughput workflows, including rapid analytical turnaround in fast-paced research settings.
  • Ability to solve complex analytical problems independently and work effectively across interdisciplinary teams spanning chemistry, screening, automation, and computational sciences.
  • Strong documentation, communication, and data interpretation skills, with a commitment to rigor, reproducibility, and scientific quality.

Bonus Points For
  • Experience with multimodal characterization approaches that combine orthogonal measurements to generate deeper insight into molecular systems and discovery workflows.
  • Experience supporting high-throughput screening, reaction screening, or automated discovery platforms.
  • Familiarity with analytical workflows integrated with robotics, liquid handlers, autosamplers, or other automation-enabled laboratory systems.
  • Experience working in AI-enabled or highly data-driven R&D environments where experimental data is used to drive predictive modeling or closed-loop optimization.
  • Knowledge of characterization approaches that extend beyond traditional compound QC, including molecular profiling, reaction analytics, and property-focused measurements.
  • Familiarity with data systems such as ELNs, LIMS, and software tools used to manage and analyze large analytical datasets.
  • Ability to operate effectively in a fast-moving, innovative environment with evolving platform needs and cross-functional priorities.
  • Strong scientific curiosity and interest in building next-generation analytical capabilities for molecular discovery.

Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Expected Base Salary Range
$148,000-$198,000 USD
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.