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High Throughput Screening Jobs in California (NOW HIRING)

Octant Bio

HTS Research Associate

Emeryville, CA · On-site

$75K - $93K/yr

Build, improve, and execute our high-throughput screening workflows leveraging automation infrastructure and data quality control processes to support robust operations at scale * Operate various ...

Octant Bio

HTS Research Associate

Emeryville, CA · On-site

$75K - $93K/yr

Build, improve, and execute our high-throughput screening workflows leveraging automation infrastructure and data quality control processes to support robust operations at scale * Operate various ...

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All JobsHigh Throughput Screening JobsHigh Throughput Screening Jobs in California

High Throughput Screening information

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How much do high throughput screening jobs pay per hour?

As of Aug 17, 2026, the average hourly pay for high throughput screening in California is $23.62, according to ZipRecruiter salary data. Most workers in this role earn between $18.75 and $27.98 per hour, depending on experience, location, and employer.

What is high throughput screening in drug discovery?

High throughput screening (HTS) is a laboratory technique used in drug discovery to quickly test thousands to millions of chemical compounds for activity against a biological target. By using automated equipment, robotics, and data analysis tools, researchers can identify potential drug candidates more efficiently than traditional methods. HTS accelerates the early stages of drug development by providing rapid, large-scale screening, which helps scientists prioritize compounds for further study. This approach is widely used in pharmaceutical research and biotechnology companies.

What are some common challenges faced in a high throughput screening role, and how can they be addressed?

One common challenge in High Throughput Screening is managing large volumes of data generated from automated assays, which requires strong data analysis skills and attention to detail. Another challenge is ensuring assay reliability and minimizing variability, which often involves close collaboration with assay development scientists and automation engineers. Effective communication within multidisciplinary teams is essential to troubleshoot issues quickly and adapt protocols as needed. Staying organized and proactively addressing equipment maintenance can also help minimize downtime and improve screening efficiency.

What are the key skills and qualifications needed to thrive as a high throughput screening scientist, and why are they important?

To thrive as a High Throughput Screening Scientist, you need a solid background in biology or chemistry, experience with assay development, and often a relevant advanced degree. Familiarity with automated liquid handling systems, data analysis software, and laboratory information management systems (LIMS) is essential. Strong problem-solving, attention to detail, and effective teamwork are standout soft skills in this role. These skills are critical for efficiently identifying potential drug candidates and ensuring accurate, reproducible results in a fast-paced research environment.

What is the difference between High Throughput Screening vs Laboratory Technician?

AspectHigh Throughput ScreeningLaboratory Technician
Required credentialsBachelor's degree in biology, chemistry, or related field; experience with automationAssociate's or bachelor's degree; basic lab skills
Work environmentResearch labs focused on drug discovery and screeningGeneral laboratory settings across various industries
Employer and industry usagePharmaceutical, biotech, research institutionsHospitals, research labs, manufacturing plants
Common search and comparison intentUnderstanding roles in drug discovery and screening processesGeneral lab work and technical support roles

High Throughput Screening specialists focus on automating and conducting large-scale testing of compounds to identify potential drug candidates, requiring specialized skills and equipment. Laboratory Technicians perform routine lab tasks across various settings, supporting research and testing processes. While both roles work in laboratory environments, their responsibilities, skills, and industry focus differ significantly.

What are popular job titles related to High Throughput Screening jobs in California?

For High Throughput Screening jobs in California, the most frequently searched job titles are:

What job categories do people searching High Throughput Screening jobs in California look for?

The top searched job categories for High Throughput Screening jobs in California are:

What cities in California are hiring for High Throughput Screening jobs?

Cities in California with the most High Throughput Screening job openings:

High Throughput Screening jobs near you
Infographic showing various High Throughput Screening job openings in California as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 16% Part Time, and 3% Contract. Highlights an 90% Physical, 1% Hybrid, and 9% Remote job distribution, with an average salary of $49,138 per year, or $23.6 per hour.

Director, High-Throughput Biology

Eikon Therapeutics

Millbrae, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 24 days ago

Job description

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon's discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.
Position
The Director, High-Throughput Biology (HTB) is responsible for the strategy, performance, and evolution of Eikon's high-throughput screening and discovery platforms. This role leads end-to-end high-throughput screening execution across automated and imaging-based platform technologies, ensuring delivery of scalable, reproducible, decision-enabling data that supports portfolio priorities. Operating at the intersection of biology, automation engineering, and computational science, this leader establishes standards for assay robustness, data quality, platform reliability, and technical execution, while building a high-performing organization capable of advancing discovery programs efficiently and at scale.
About You
You are a strategic and technically grounded leader who brings deep expertise in high-throughput screening and platform biology, along with the ability to lead across biology, automation, and computational disciplines. You are comfortable operating at both the strategic and technical level, balancing organizational leadership with hands-on scientific engagement where needed. You bring strong judgment, cross-functional leadership, and a commitment to building scalable, resilient systems that support high-quality discovery execution. You are also experienced in developing teams, strengthening technical depth, and creating shared ownership across critical workflows and capabilities.
What You'll Do
  • Set the vision and operating model for HTB, defining strategy, success metrics, and standards that ensure sustainable, reliable, high-quality screening data delivery across the portfolio.
  • Partner cross-functionally at the assay-to-screening interface to align assay readiness, screening feasibility, platform capabilities, and project priorities.
  • Lead high-throughput screening strategy and execution, partnering with HTB scientists and program leadership to drive prioritization, ensure feasibility, and enable data-driven decisions.
  • Optimize team resourcing and representation to support screening design, execution, analysis, and program engagement across scientists and SRAs.
  • Lead an integrated platform organization that aligns biology, automation, and data analytics into a cohesive screening engine, including workflows, robotics integration, quality control, reporting, and data practices.
  • Build, develop, and retain a high-performing team through clear accountability, coaching, and development of technical and cross-functional capability.
  • Provide hands-on technical leadership by shaping assay strategy, screening design, analytical methods, and data or automation tooling where needed.
  • Establish scalable practices through documentation, playbooks, and shared ownership of critical workflows and code to strengthen continuity and reduce single-point dependency.

Qualifications
  • PhD in Biological Sciences, Computational Sciences, or a related discipline with 10+ years of experience in high-throughput or high-content screening environments.
  • Demonstrated expertise with automated screening platforms, including 384- and/or 1536-well formats.
  • Experience screening compound libraries larger than 100k.
  • Experience advancing drug discovery programs from hit identification through lead optimization.
  • Experience with microscopy-based or imaging-enabled screening platforms.
  • Experience with genetic screens or systems biology approaches.
  • Strong expertise in statistical analysis and large-scale dataset quality control, with proficiency in Python.
  • Experience building or contributing to scalable data processing pipelines.
  • Proficiency with compound databases, LIMS, and enterprise data systems.
  • Proven cross-functional leadership across biology, chemistry, engineering, and data teams.
  • Experience with single-molecule imaging technology is preferred.
  • Experience with novel technologies or assay development for drug discovery is preferred.
  • Strong computational science capability and familiarity with machine learning or artificial intelligence applications in phenotypic or multiparametric screening are preferred.
  • Demonstrated ability to build hybrid biology and computational teams is preferred.

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:
  • 401k plan with company matching
  • Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
  • Mental health and wellness benefits
  • Weeklong summer and winter holiday shutdowns
  • Generous paid time off and holiday policies
  • Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies
  • Enhanced parental leave benefit
  • Daily subsidized lunch program when on-site

The expected salary range for this role is $213,000 to $257,250 depending on skills, competency, and the market demand for your expertise.
Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.
We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.

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