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High Throughput Screening information

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How much do high throughput screening jobs pay per hour?

As of Jul 13, 2026, the average hourly pay for high throughput screening in the United States is $23.94, according to ZipRecruiter salary data. Most workers in this role earn between $18.99 and $28.37 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a High Throughput Screening (HTS) Scientist, and why are they important?

To thrive as a High Throughput Screening Scientist, you need a solid background in biology or chemistry, experience with assay development, and often a relevant advanced degree. Familiarity with automated liquid handling systems, data analysis software, and laboratory information management systems (LIMS) is essential. Strong problem-solving, attention to detail, and effective teamwork are standout soft skills in this role. These skills are critical for efficiently identifying potential drug candidates and ensuring accurate, reproducible results in a fast-paced research environment.

What is high throughput screening in drug discovery?

High throughput screening (HTS) is a laboratory technique used in drug discovery to quickly test thousands to millions of chemical compounds for activity against a biological target. By using automated equipment, robotics, and data analysis tools, researchers can identify potential drug candidates more efficiently than traditional methods. HTS accelerates the early stages of drug development by providing rapid, large-scale screening, which helps scientists prioritize compounds for further study. This approach is widely used in pharmaceutical research and biotechnology companies.

What are some common challenges faced in a High Throughput Screening (HTS) role, and how can they be addressed?

One common challenge in High Throughput Screening is managing large volumes of data generated from automated assays, which requires strong data analysis skills and attention to detail. Another challenge is ensuring assay reliability and minimizing variability, which often involves close collaboration with assay development scientists and automation engineers. Effective communication within multidisciplinary teams is essential to troubleshoot issues quickly and adapt protocols as needed. Staying organized and proactively addressing equipment maintenance can also help minimize downtime and improve screening efficiency.

What is the difference between High Throughput Screening vs Laboratory Technician?

AspectHigh Throughput ScreeningLaboratory Technician
Required credentialsBachelor's degree in biology, chemistry, or related field; experience with automationAssociate's or bachelor's degree; basic lab skills
Work environmentResearch labs focused on drug discovery and screeningGeneral laboratory settings across various industries
Employer and industry usagePharmaceutical, biotech, research institutionsHospitals, research labs, manufacturing plants
Common search and comparison intentUnderstanding roles in drug discovery and screening processesGeneral lab work and technical support roles

High Throughput Screening specialists focus on automating and conducting large-scale testing of compounds to identify potential drug candidates, requiring specialized skills and equipment. Laboratory Technicians perform routine lab tasks across various settings, supporting research and testing processes. While both roles work in laboratory environments, their responsibilities, skills, and industry focus differ significantly.

More about High Throughput Screening jobs
What cities are hiring for High Throughput Screening jobs? Cities with the most High Throughput Screening job openings:
What states have the most High Throughput Screening jobs? States with the most job openings for High Throughput Screening jobs include:
What job categories do people searching High Throughput Screening jobs look for? The top searched job categories for High Throughput Screening jobs are:
High Throughput Screening jobs near you
Infographic showing various High Throughput Screening job openings in the United States as of July 2026, with employment types broken down into 96% Full Time, and 4% Part Time. Highlights an 100% In-person job distribution, with an average salary of $49,790 per year, or $23.9 per hour.
Scientist - High-Throughput Screening & Analytical Chemistry

Scientist - High-Throughput Screening & Analytical Chemistry

Manus Bio

Waltham, MA • On-site

Full-time

Re-posted 24 days ago

Job description

Scientist - High-Throughput Screening & Analytical Chemistry - Waltham, MA, Full-time
Manus works across industries and value chains to accelerate the transition to BioAlternatives - better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biotechnology today.
We are seeking a Scientist in Screening & Analytical Chemistry to lead development of high-throughput analytical workflows. This role focuses on method development for rapid, targeted metabolite quantification and integration with screening pipelines.
This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus's research and development team located in Waltham, MA.
Why work at Manus:
  • Opportunity - For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability - You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion - We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities
  • Develop and optimize analytical methods for targeted metabolite quantification
  • Lead method development on GC/MS, GC-FID, and LC-QQQ-MS platforms
  • Design high-throughput analytical workflows with fast cycle times
  • Develop sample preparation and derivatization strategies
  • Work with automation and screening teams to support microtiter plate-based fermentations
  • Analyze and interpret large datasets
  • Mentor junior staff
  • Interface with instrument vendors to maintain uptime and optimal performance
  • Author SOPs and technical reports

Basic Qualifications
  • PhD in Analytical Chemistry, Chemistry, or related field OR
  • MS with 8+ years or BS with 13+ years relevant experience
  • Strong experience in analytical method development

Required Technical Expertise
  • GC-FID and GC/MS assay development for targeted quantitation and metabolite profiling
  • LC/QQQ-MS assay develop for targeted quantitation
  • Assay optimization for speed, sensitivity, and throughput

Preferred Experience
  • Experience with high-throughput screening environments
  • Integration of analytical workflows with automation
  • Familiarity with liquid handling platforms
  • Experience with LIMS (e.g. Benching) and large datasets
  • Industrial biotech or applied R&D experience
  • Experience with the following types of analytical instrumentation
    • UHPLC
    • GC-FID
    • GC/MS
    • LC/QQQ-MS
  • Experience with a variety of sample extraction and preparation techniques, applying automated solutions when appropriate, from complex matrices
    • Microbial fermentation broth
    • Microbial biomass
    • Purified extracts

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