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Oligonucleotide Jobs (NOW HIRING)

GSK

Scientist, Oligonucleotide Synthesis

Cambridge, MA · On-site

$96K - $160K/yr

Support pre-clinical oligonucleotide high-throughput and mid-scale synthesis capabilities of ASOs, siRNA, SSO, and RNA editors with routine and novel next generation amidite chemistries. * Perform ...

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How much do oligonucleotide jobs pay per hour?

As of Jul 27, 2026, the average hourly pay for oligonucleotide in the United States is $23.35, according to ZipRecruiter salary data. Most workers in this role earn between $18.27 and $26.44 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Oligonucleotide position, and why are they important?

To thrive in an Oligonucleotide Specialist or Research Scientist role, a background in molecular biology, biochemistry, or a related life science—usually with a bachelor’s or advanced degree—is essential. Familiarity with DNA/RNA synthesis platforms, analytical instruments like HPLC and mass spectrometry, and quality control processes is crucial, along with knowledge of relevant regulatory standards. Attention to detail, strong problem-solving abilities, and effective teamwork skills help individuals excel in a laboratory environment. These competencies ensure precise design, synthesis, and validation of oligonucleotides, which are critical for quality research and development in biotechnology.

What is an Oligonucleotide job?

An Oligonucleotide job typically involves the synthesis, purification, analysis, and quality control of short DNA or RNA sequences used in research, diagnostics, and therapeutics. Professionals in this role may work in biotechnology, pharmaceutical, or academic settings, ensuring the accurate production of oligonucleotides for applications such as PCR, gene editing, and drug development. Responsibilities often include operating automated synthesizers, troubleshooting synthesis issues, and maintaining laboratory protocols. Strong knowledge of molecular biology, chemistry, and instrumentation is essential.

What typical responsibilities does an Oligonucleotide Specialist handle day-to-day, and how does the role collaborate with others in the lab?

Oligonucleotide Specialists are primarily responsible for synthesizing, purifying, and characterizing short strands of DNA or RNA according to project specifications, often following strict protocols to ensure accuracy and reproducibility. They frequently utilize specialized laboratory equipment and maintain detailed records to support quality control and reporting requirements. Collaboration is integral, as they often work closely with molecular biologists, chemists, and quality assurance teams to troubleshoot issues and meet project deadlines. This teamwork enhances the development of custom oligonucleotides for research, diagnostics, or therapeutic applications.

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What cities are hiring for Oligonucleotide jobs? Cities with the most Oligonucleotide job openings:
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Oligonucleotide jobs near you
Infographic showing various Oligonucleotide job openings in the United States as of July 2026, with employment types broken down into 97% Full Time, and 3% Contract. Highlights an 90% Physical, 5% Hybrid, and 5% Remote job distribution, with an average salary of $48,570 per year, or $23.4 per hour.
Oligonucleotide Scientist

Oligonucleotide Scientist

Aequor

South San Francisco, CA • On-site

Other

This job post has expired today. Applications are no longer accepted.

Job description

Job Details:

Title: Oligonucleotide Scientist

Location: South San Francisco, CA (Onsite)

Duration: 12+ Months Contract (Extendable)


Job Description

*** Hands-on expertise in oligonucleotide therapeutics discovery, synthesis, and nucleic acid chemistry to support RNAi drug discovery programs.

** BS/MS degree in Chemistry or a related scientific discipline.

** Hands-on experience with automated oligonucleotide synthesizers, oligonucleotide synthesis, purification, and characterization techniques.

** Strong experience with analytical platforms including HPLC and Mass Spectrometry for oligonucleotide purification, characterization, and impurity profiling.

** Knowledge of RNAi therapeutics and nucleic acid therapeutic modalities within pharmaceutical or biotechnology research environments.

** Preferred experience in large molecule drug discovery, oligonucleotide delivery technologies, or bioconjugation approaches.

Education

*A minimum of a Bachelor's degree is required for this role. Candidates with a Ph.D. may be considered overqualified for the position.


Thanks & Regards,

Sanjay Kumar Lead Recruiter - Staffing

Aequor Technologies LLC

377 Hoes Lane, Suite 300

Piscataway, NJ 08854

Ph: 732-289-3815 || sanjay.kumar@aequor.com

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