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How much do high throughput screening jobs pay per hour?

As of Jun 7, 2026, the average hourly pay for high throughput screening in the United States is $23.94, according to ZipRecruiter salary data. Most workers in this role earn between $18.99 and $28.37 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a High Throughput Screening (HTS) Scientist, and why are they important?

To thrive as a High Throughput Screening Scientist, you need a solid background in biology or chemistry, experience with assay development, and often a relevant advanced degree. Familiarity with automated liquid handling systems, data analysis software, and laboratory information management systems (LIMS) is essential. Strong problem-solving, attention to detail, and effective teamwork are standout soft skills in this role. These skills are critical for efficiently identifying potential drug candidates and ensuring accurate, reproducible results in a fast-paced research environment.

What is high throughput screening in drug discovery?

High throughput screening (HTS) is a laboratory technique used in drug discovery to quickly test thousands to millions of chemical compounds for activity against a biological target. By using automated equipment, robotics, and data analysis tools, researchers can identify potential drug candidates more efficiently than traditional methods. HTS accelerates the early stages of drug development by providing rapid, large-scale screening, which helps scientists prioritize compounds for further study. This approach is widely used in pharmaceutical research and biotechnology companies.

What are some common challenges faced in a High Throughput Screening (HTS) role, and how can they be addressed?

One common challenge in High Throughput Screening is managing large volumes of data generated from automated assays, which requires strong data analysis skills and attention to detail. Another challenge is ensuring assay reliability and minimizing variability, which often involves close collaboration with assay development scientists and automation engineers. Effective communication within multidisciplinary teams is essential to troubleshoot issues quickly and adapt protocols as needed. Staying organized and proactively addressing equipment maintenance can also help minimize downtime and improve screening efficiency.

What is the difference between High Throughput Screening vs Laboratory Technician?

AspectHigh Throughput ScreeningLaboratory Technician
Required credentialsBachelor's degree in biology, chemistry, or related field; experience with automationAssociate's or bachelor's degree; basic lab skills
Work environmentResearch labs focused on drug discovery and screeningGeneral laboratory settings across various industries
Employer and industry usagePharmaceutical, biotech, research institutionsHospitals, research labs, manufacturing plants
Common search and comparison intentUnderstanding roles in drug discovery and screening processesGeneral lab work and technical support roles

High Throughput Screening specialists focus on automating and conducting large-scale testing of compounds to identify potential drug candidates, requiring specialized skills and equipment. Laboratory Technicians perform routine lab tasks across various settings, supporting research and testing processes. While both roles work in laboratory environments, their responsibilities, skills, and industry focus differ significantly.

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High Throughput Screening jobs near you
Infographic showing various High Throughput Screening job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 88% In-person, and 12% Hybrid job distribution, with an average salary of $49,790 per year, or $23.9 per hour.
Research Associate / Sr. Research Associate - Automation & Screening

Research Associate / Sr. Research Associate - Automation & Screening

Manus Bio

Waltham, MA • On-site

Full-time

Posted 17 days ago

Job description

Research Associate / Sr. Research Associate - Automation & Screening, Waltham, MA -Full-time
Manus works across industries and value chains to accelerate the transition to BioAlternatives - better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of biotechnology today.
Manus is seeking a Research Associate (RA) or Senior Research Associate (SRA) to support high-throughput screening (HTS) and laboratory automation workflows to identify engineered microbial strains with enhanced performance. This role focuses on execution of screening campaigns, automation, and sample preparation in a fast-paced, cross-functional environment.
This hands-on position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative. This person will be expected to play an integral part of Manus's research and development team located in Waltham, MA.
Why work at Manus:
  • Opportunity - For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability - You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion - We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities
  • Execute high-throughput screening workflows in microtiter plate formats
  • Operate and maintain automated liquid handling platforms (e.g., Tecan, Bravo)
  • Perform automated and manual sample preparation workflows
  • Support plate-based cultivation and screening experiments
  • Ensure accurate data collection, processing, and upload to LIMS systems
  • Collaborate with cross-functional teams to execute screening campaigns
  • Collaborate with Fermentation teams to enhance plate to bioreactor predictions
  • Troubleshoot and optimize automation workflows
  • Maintain instrumentation readiness and lab organization
  • Author and update SOPs and documentation
  • Ensure compliance with EH&S standards

Basic Qualifications
  • Research Associate: Bachelor's degree with 0-4 years' experience
  • Senior Research Associate: Bachelor's with 4-7 years' or Master's with 2-4 years' experience
  • Degree in biology, chemistry, bioengineering, or related field
  • Experience with automation, liquid handling, or screening workflows

Preferred Experience
  • Experience with Tecan, Bravo, or similar liquid handling systems
  • Experience supporting high-throughput screening campaigns
  • Experience with LIMS systems (e.g., Benchling)
  • Data analysis experience (JMP, Python, SQL)
  • Familiarity with analytical instrumentation (GC, LC, MS)
  • Experience with sample extraction and preparation from microbial fermentation broth

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