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Downstream Process Jobs in Indiana (NOW HIRING)

... downstream finishing, stamping, tooling, and tubing. We offer an excellent total compensation ... process, please send an e-mail to careers@clevelandcliffs.com or call 1-(312) 899-3097 and let us ...

The Process Technician is responsible for the setup, monitoring, and optimization of plastic ... Set up and operate secondary or downstream equipment as needed. * Perform routine preventive ...

The Process Technician is responsible for the setup, monitoring, and optimization of plastic ... Set up and operate secondary or downstream equipment as needed. * Perform routine preventive ...

The Process Technician is responsible for the setup, monitoring, and optimization of plastic ... Set up and operate secondary or downstream equipment as needed. * Perform routine preventive ...

Postdoctoral Fellow

Bloomington, IN ยท On-site

$45K - $61K/yr

The primary goal of the lab is to characterize the role of nuclear pore complex machinery in mediating HIV-1 nuclear entry and subsequent downstream process that leads to productive viral gene ...

Production and Manufacturing Downstream Worker Type: Regular Posting Start Date: July 9, 2026 ... Perform in-process analytical testing, analyze in-process test results, and apply appropriate ...

Process Operator

Michigan City, IN ยท On-site

$37.59/hr

Production and Manufacturing Downstream Worker Type: Regular Posting Start Date: July 6, 2026 ... Perform in-process analytical testing, analyze in-process test results, and apply appropriate ...

Senior Quality Systems Engineer

Spencer, IN ยท On-site

$76K - $103K/yr

... and downstream process owners to maintain effective integration between Global Risk Management and related quality system processes, including Design Controls, Production and Process Controls ...

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Downstream Process information

See Indiana salary details

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How much do downstream process jobs pay per hour?

As of Jul 10, 2026, the average hourly pay for downstream process in Indiana is $23.48, according to ZipRecruiter salary data. Most workers in this role earn between $18.75 and $26.78 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What cities in Indiana are hiring for Downstream Process jobs? Cities in Indiana with the most Downstream Process job openings:
Infographic showing various Downstream Process job openings in Indiana as of July 2026, with employment types broken down into 18% Locum Tenens, 73% Full Time, 6% Part Time, 2% Contract, and 1% Summer. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $48,833 per year, or $23.5 per hour.

Operations Support Specialist (OSS)

Samtec, Inc Careers

New Albany, IN โ€ข On-site

$47K - $63K/yr

Other

Posted 15 days ago


Job description

Description
Position at Samtec, Inc

JOB DESCRIPTION

Job title:ย  OPERATIONS SUPPORT SPECIALIST (OSS)ย 

Monday-Friday 8am-4:30pm

Summary/Objective:ย  The Operations Support Specialist (OSS) will be responsible for the material flow in the production work centers and will coordinate and communicate to cross functional sections, upstream and downstream production work centers to manage the order flow until customer delivery.

Essential Functions/ Responsibilities:

  • Schedule and plan the order by using Scheduling Dashboard or any other equivalent tool to meet the MDD (Manufacturing Due Date) by ensuring the material, people and machine capacity availability.
  • Look for the opportunities to batch orders to minimize changeovers without compromising due dates.
  • Communicate and coordinate with other shift supervisors to ensure smooth execution according to the plan.
  • Monitor, manage and follow through (physically locate) on orders to ensure they flow through the processes and are on track to meet the MDD. Proactively work with relevant parties to address any potential issues to avoid any past due orders.
  • Report to Supervisor when there is any risk that an order may miss the due date.
  • Follow up with material planner or upstream process on material requirement for orders.
  • Drive OTD improvements to achieve the target by working with relevant parties to close the gap (example: material availability, machine downtime, insufficient lead time etc.).
  • Ensure correct reschedule code is entered together with realistic date for any order that is past due.
  • Inform appropriate departments especially the downstream process / work center of orders that deviate from the schedule so that opportunities of recovery can be explored.
  • Utilize reports to proactively manage large orders (example Daily Order Report and Pocket Report) to meet the MDD.
  • Assume supervisor responsibilities during the absence of the Supervisor including but not limited to: Pass down, order traceability, expedites, dashboard, and personnel management.
  • Responsible for pulling in material in a 7-day window or any other window set up by the Supervisor, updating material comments according to the production plan, (examples: reviewing PO transactions, shipment due dates, materials in transit), and expediting Planners when needed.
  • Responsible for printing shop orders and creating materials sessions, based on the window assigned by the supervisor.
  • Responsible for creating parcel ID's for parts that go to Sudden Saving.
  • Responsible for following up material arrival with shipment packing list and prioritizing material needs on the production floor

* The responsibilities as defined are intended to serve as a general guideline for this position. Associates may be asked to perform additional tasks depending on strengths and capabilities. *ย 

Required/Preferred Experience:

  • Minimum of 3 years' experience in manufacturing is desired.
  • Proficient with Samtec Global Network (SGN), Shop Floor Control, PC Man, Inventory Suite, Pocket Database etc.
  • Excellent problem-solving skills, investigative skills, and detail oriented
  • Must possess good communication skills - written and verbal.
  • Must be able to use Microsoft Software (Outlook, Excel, Word, Access)
  • Team player and must be able to work with multiple groups of people - Operators, Floor Mgr.'s, Engineers, etc.
  • Must be able to sit/stand for at least 90 consecutive minutes.
  • Lifting Requirements: Must be able to lift up to 50 pounds from floor to waist.
  • Hazards and Atmospheric Conditions: Must be willing to adhere to department safety rules and regulations.ย  May be exposed to noise (required to wear protective gear).ย  May be exposed to Hazardous Materials & Chemicals (required to wear safety glasses and other protective gear).

Education:ย 

  • High School diploma or equivalent is required.ย 
  • College education (4 year Bachelor's Degree in applicable fields)ย 

Training required: On the job training as appropriate

Languages:ย  Englishย 


SAMTEC, Inc. is an Equal Opportunity Employer and committed to creating a diverse environment. All employment decisions at Samtec are based in business needs, job requirements and individual qualifications, without regard to race, color, religion or belief, national, social or ethnic origin, pregnancy or parental status, age, disability, sexual orientation, gender and/or gender identity/expression, marital status, past or present military service, family medical history or genetic information, or any other status protected by applicable laws. Privacy Policy: https://www.samtec.com/about/legal/#privacyrightspage