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Downstream Process Jobs in Georgia (NOW HIRING)

Manus

Pilot Plant Downstream Processing Operator

Augusta, GA · On-site

$15 - $19/hr

Interface with process development team to provide resources to solve fermentation and product ... Perform downstream purification operations including centrifugation, chromatography (e.g., affinity ...

RWDC Industries

Be Seen First

Process Technician

Athens, GA · On-site

$45K - $45K/yr

Process Technicians (Immediate Openings) Process Technician operating production scale bioreactors and downstream processing equipment. We are a rapidly growing biotechnology company currently ...

Ring Container Technologies

Downstream Operator

Valdosta, GA · On-site

$14 - $16.50/hr

Document machine or process changes. * Perform necessary downstream operator checklists. * Maintain accurate production reporting documentation. Responsible for active participation on plant teams ...

Ring Container Technologies

Downstream Operator-1

Valdosta, GA · On-site

$13.50 - $17.50/hr

Document machine or process changes. * Perform necessary downstream operator checklists. * Maintain accurate production reporting documentation. Responsible for active participation on plant teams ...

Ring Container Technologies

Downstream Operator-1

Valdosta, GA · On-site

$13.50 - $17.50/hr

Document machine or process changes. * Perform necessary downstream operator checklists. * Maintain accurate production reporting documentation. Responsible for active participation on plant teams ...

Mohawk Industries

Manufacturing Engineer

Dalton, GA · On-site

$59K - $76K/yr

Work hand-in-hand with production, maintenance, quality, automation, R&D, and upstream/downstream process teams to improve process stability, reliability, product performance, and cost.

Advanced Drainage Systems

Downstream Technician

Perry, GA

$19.50 - $26/hr

We value diverse perspectives, recognizing that they drive better ideas, processes, and performance. Our workplace is built on respect, inclusivity, and shared responsibility, ensuring every team ...

Manus

Pilot Plant Fermentation Operator

Augusta, GA · On-site

Work as a member of the pilot plant team which includes assisting both with fermentation and downstream work assignments. Controls, monitors, and measures processes as instructed. Abides by all ...

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Downstream Process information

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How much do downstream process jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for downstream process in Georgia is $20.83, according to ZipRecruiter salary data. Most workers in this role earn between $16.63 and $23.75 per hour, depending on experience, location, and employer.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What are popular job titles related to Downstream Process jobs in Georgia?

For Downstream Process jobs in Georgia, the most frequently searched job titles are:

What job categories do people searching Downstream Process jobs in Georgia look for?

The top searched job categories for Downstream Process jobs in Georgia are:

Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Georgia as of August 2026, with employment types broken down into 1% As Needed, 74% Full Time, 15% Part Time, 7% Contract, and 3% Nights. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $43,333 per year, or $20.8 per hour.

Pilot Plant Downstream Processing Operator

Manus Bio

Augusta, GA • On-site

$17.75 - $22.50/hr

Full-time

Re-posted 2 days ago

Job description

Pilot Plant Downstream Processing Operator
Manus
Manus works across industries and value chains to accelerate the transition to BioAlternatives � better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self-motivated and highly organized individual for a position that will specialize in laboratory operations at our Augusta BioFacility.
Why work at Manus:
  • Opportunity � For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability � You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion � We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Responsibilities:
  • Interface with process development team to provide resources to solve fermentation and product isolation challenges. Execute and help evaluate experiments. This activity includes:
  • Perform downstream purification operations including centrifugation, chromatography (e.g., affinity, ion exchange), filtration (TFF, depth, sterile).
  • Set up, operate, and clean process equipment such as columns, tanks, and filtration systems.
  • Collect, label, and process in-process and final product samples.
  • Monitor process parameters, record data, and ensure batch documentation is completed accurately.
  • Perform cleaning and sterilization of equipment and cleanroom areas (CIP/SIP procedures).
  • Assist in deviation investigations and continuous improvement initiatives.
  • Collaborate with upstream and quality departments to ensure efficient process flow and product quality.
  • Maintain inventory of DSP consumables and request resupply as needed.
  • Become familiar with all required batch records, execute according to the batch records and ensure clear communication of the targeted design parameters.
  • Execute day-to-day Pilot Plant activities, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
  • Maintain the upkeep of the Pilot Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; Be capable of correcting minor maintenance issues.
  • Adhere to company environmental, safety, and health policies and procedure. Ensure Pilot Plant compliance with safety and environmental regulations.
  • Physical demand requirements are more than sedentary work due to inspection of equipment. Must be able to climb stairs and ladders. Must be able to lift 50 pounds.

Working Hazards and Conditions:
  • This position involves work on the third floor of the facility and requires occasional manual handling of hazardous materials, including carrying pitchers of sulfuric acid and glassware (such as beakers, flasks, and similar lab equipment).
  • The role also involves working around hot steam tanks, requiring strict adherence to safety procedures and use of appropriate personal protective equipment (PPE) at all times.
  • At certain times, the employee may be required to work alone, necessitating compliance with Manus Bio's lone worker safety protocols to ensure proper communication and emergency preparedness.
  • Employees must maintain a heightened awareness of their surroundings, follow all established chemical handling and steam safety procedures, and participate in mandatory hazard and emergency response training.
  • Must be able to wear the required protective equipment, including respirators when needed.
  • Work schedule is considered shift but will vary depending on manufacturing plan and other extraordinary conditions.

Required Qualifications:
  • High school diploma or GED equivalent.
  • Minimum of 3 years downstream or related plant operator experience.
  • Must be able to follow minimal instructions and support safe work practices.
  • Must be an excellent team member with strong communication skills and a desire to work collaboratively.
  • Must be flexible with day-to-day duties and able to thrive in a start-up environment.
  • Must hold themselves to the highest professional and ethical standards.
  • Some familiarity with the production fermentation and downstream processes and equipment as well as microbiological and analytical laboratory procedures.
  • Demonstrates flexibility in job rotations/various assignments.
  • Basic PC skills which include Windows, Microsoft Office.

Preferred Qualification and Working Style:
  • SAP skills
  • Certified Train the Trainer skills
  • Delta V controls experience

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