ZipRecruiter

Log In

1

Downstream Process Jobs in Georgia (NOW HIRING)

Manus Bio

Downstream Processing Operator

Augusta, GA · On-site

This person will be expected to play an integral part of Manus Bio's manufacturing and process development team located in Augusta, GA. The Downstream Processing Operator is responsible for the ...

Manus Bio

Downstream Processing Operator

Augusta, GA

$17.75 - $22.50/hr

This person will be expected to play an integral part of Manus Bios manufacturing and process development team located in Augusta, GA. The Downstream Processing Operator is responsible for the ...

Manus

Downstream Processing Operator

Augusta, GA · On-site

This person will be expected to play an integral part of Manus Bio's manufacturing and process development team located in Augusta, GA. The Downstream Processing Operator is responsible for the ...

RWDC Industries

Be Seen First

Process Technician

Athens, GA · On-site

$45K - $45K/yr

Process Technicians (Immediate Openings) Process Technician operating production scale bioreactors and downstream processing equipment. We are a rapidly growing biotechnology company currently ...

Orbia

Downstream Operator

Tennille, GA

$17.25/hr

Every part of the manufacturing process is monitored with environmentally friendly sustainable ... Dura-Line Downstream Operator Company : Dura-Line, an Orbia Business Job Title: Entry-Level Conduit ...

Orbia

Downstream Operator

Tennille, GA · On-site

$17.25/hr

Every part of the manufacturing process is monitored with environmentally friendly sustainable ... Dura-Line Downstream Operator Company : Dura-Line, an Orbia Business Job Title: Entry-Level Conduit ...

Manus Bio

Pilot Plant Operator Apprentice

Augusta, GA · On-site

Downstream Processing (DSP) * Learn and perform downstream purification operations including centrifugation, filtration (TFF, depth, sterile), and basic chromatography under supervision. * Assist ...

Manus

Pilot Plant Operator Apprentice

Augusta, GA

Downstream Processing (DSP) * Learn and perform downstream purification operations including centrifugation, filtration (TFF, depth, sterile), and basic chromatography under supervision. * Assist ...

Mativ Holdings, Inc.

Process Engineer I

Athens, GA · On-site

The Process Engineer supports and improves manufacturing operations within a plastics extrusion ... Equipment, Tooling & Technology Support die design, calibration tooling, and downstream equipment ...

Mativ

Process Engineer I

Athens, GA · On-site

Process Engineer I Mativ is a global leader in specialty materials headquartered in Alpharetta ... Equipment, Tooling & Technology Support die design, calibration tooling, and downstream equipment ...

Nexus Circular

Process Engineering Lead

Atlanta, GA · On-site

$99K - $129K/yr

... downstream • Smooth transitions from FEL → FEED → EPC • Strong EPC alignment and reduced ... understanding of process safety, operability, and design standards (API, ASME, etc.) • ...

Nexus Circular

Process Engineering Lead

Atlanta, GA · On-site

$99K - $129K/yr

... downstream · Smooth transitions from FEL → FEED → EPC · Strong EPC alignment and reduced ... process safety, operability, and design standards (API, ASME, etc.) · Comfortable working in ...

Advanced Drainage Systems

Downstream Technician

Perry, GA

$19.50 - $26/hr

We value diverse perspectives, recognizing that they drive better ideas, processes, and performance. Our workplace is built on respect, inclusivity, and shared responsibility, ensuring every team ...

next page

Showing results 1-20

All JobsDownstream Process JobsDownstream Process Jobs in Georgia

Downstream Process information

See Georgia salary details

$11

$20

$30

How much do downstream process jobs pay per hour?

As of Jun 13, 2026, the average hourly pay for downstream process in Georgia is $20.83, according to ZipRecruiter salary data. Most workers in this role earn between $16.63 and $23.75 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Georgia? For Downstream Process jobs in Georgia, the most frequently searched job titles are:
What job categories do people searching Downstream Process jobs in Georgia look for? The top searched job categories for Downstream Process jobs in Georgia are:
Downstream Process jobs near you
Downstream Processing Operator

Downstream Processing Operator

Manus Bio

Augusta, GA • On-site

Full-time

Posted 13 days ago

Job description

Manus works across industries and value chains to accelerate the transition to BioAlternatives - better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a highly motivated Fermentation Plant Operator. This person will be expected to play an integral part of Manus Bio's manufacturing and process development team located in Augusta, GA.
The Downstream Processing Operator is responsible for the continuing efficient operation of the fermentation plant and providing overtime support as needed for production. This includes maintenance, equipment reliability, and operations. Creativity and decision-making skills are required. Must be able to maintain a good working relationship with all personnel. Work as a member of the fermentation plant team which includes assisting in the Pilot Plant. Controls, monitors, and measures fermentation processes as instructed. Abides by all safely, environmental, and quality requirements. Perform minor maintenance and duties related to product testing, including sampling.
Why work at Manus Bio:
  • Opportunity - For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
  • Accountability - You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
  • Passion - We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Responsibilities:
Interface with production to provide resources to solve fermentation and product isolation problems and help evaluate fermentation experiments. This activity includes:
  • Prepare fermentation and downstream equipment in accordance to SOPs, this include equipment setup, media make up, equipment disassembly, cleaning, etc.
  • Collect samples during manufacturing process for analytical analysis.
  • Prepare all required batch records, reflect constantly changing experimental designs and ensure clear communication to the process development subject matter expert of the targeted design parameters.
  • Collect and review all batch records. Data reduction includes electronic data conversion into and formatting in Excel for purposes of trending key operational parameters. Data is reviewed and checked. Off-line analytical data is reviewed for accuracy, retesting if necessary. Final results are organized and distributed to the process development subject matter expert.
  • Coordinate day-to-day Fermentation Plant activities, including manufacturing scheduling conflicts, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
  • Prepare SOP for new process or operations as needed.
  • Assist and provide hands-on support of Fermentation Plant maintenance activities, including rebuilding of probes and housings, changing out gear boxes on vessels, rebuilding valves, piping modifications, and modifying/fabricating new and existing equipment.
  • Maintain the upkeep of the Fermentation Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; Use your own tools to correct minor maintenance issues is encouraged.
  • Adhere to company EH&S policies and procedure. Ensure fermentation plant compliance with safety and environmental regulations.
  • Physical demand requirements are in excess of sedentary work due to inspection of equipment. Must be able to climb stairs and ladders.
  • Must be able to wear required protective equipment including respirators (if needed).
  • Work schedule is considered shift but will vary depending on manufacturing plan and and other extraordinary conditions.
  • Ensure Fermentation plant compliance with safety and environmental regulations.

Required Qualifications:
High school diploma or GED equivalent.
  • Minimum of 3 years fermentation or related plant operator experience.
  • Must be able to follow minimal instructions and support safe work practices.
  • Must be an excellent team member with strong communication skills and a desire to work collaboratively.
  • Must be flexible with day-to-day duties and able to thrive in a start-up environment.
  • Must hold themselves to the highest professional and ethical standards.
  • Familiar with the production fermentation and downstream processes and equipment as well as microbiological and analytical laboratory procedures.
  • Demonstrates flexibility in job rotations/various assignments.
  • Basic PC skills which include Windows, Microsoft Office.

Preferred Qualification and Working Style:
  • SAP skills
  • Certified Train the Trainer skills
  • Delta V controls experience

Job Type: Regular, Full-Time
Employee Status: Permanent

Apply