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Director Program Management Jobs in Needham, MA (NOW HIRING)

Alkermes

Director, Clinical Program Management

Waltham, MA · On-site

$220K - $235K/yr

... management, oversight, and execution of clinical programs in support of Alkermes' R&D portfolio ... direct reports fostering talent development, performance management, and a culture aligned with ...

Alkermes

Director, Clinical Program Management

Waltham, MA · Hybrid

$220K - $235K/yr

... management, oversight, and execution of clinical programs in support of Alkermes' R&D portfolio ... Provides oversight and support to direct reports fostering talent development, performance ...

PTC

PMO Lead/Program Director

Boston, MA

Program Director * Own program governance and ensure alignment with customer business objectives and PTC strategic vision. * Develop and manage multi-year roadmaps for PLM/ALM adoption and ...

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Director Program Management information

See Needham, MA salary details

$34.9K

$118.8K

$199.4K

How much do director program management jobs pay per year?

As of Aug 7, 2026, the average yearly pay for director program management in Needham, MA is $118,800.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,600.00 and $126,900.00 per year, depending on experience, location, and employer.

How does a director of program management typically collaborate with cross-functional teams to drive project success?

Directors of Program Management play a pivotal role in aligning cross-functional teams—such as engineering, product, marketing, and operations—to ensure that complex projects are delivered on time and within scope. They facilitate regular communication, resolve interdepartmental conflicts, and coordinate resources to keep everyone moving toward shared goals. This role often requires balancing strategic oversight with hands-on problem-solving, as well as fostering a collaborative culture that enables team members to contribute their expertise effectively. Strong relationship-building and negotiation skills are essential to proactively address challenges and maintain momentum across multiple initiatives.

What does a director of program management do?

A Director of Program Management oversees multiple projects or programs within an organization, ensuring they align with the company's strategic goals. They are responsible for setting priorities, allocating resources, and managing teams of project managers. This role involves coordinating across departments, mitigating risks, and ensuring that programs are delivered on time and within budget. Directors of Program Management also communicate with executive leadership and stakeholders to report on progress and outcomes.

What are the key skills and qualifications needed to thrive as a director of program management?

To thrive as a Director of Program Management, you need extensive experience in program and project management, a relevant degree (often in business or engineering), and proven leadership abilities. Familiarity with tools like Microsoft Project, Jira, and portfolio management software, along with certifications such as PMP or PgMP, is typically required. Exceptional communication, strategic thinking, and stakeholder management skills distinguish top performers in this role. These skills ensure the effective delivery of complex initiatives, alignment with organizational goals, and strong cross-functional collaboration.
What job categories do people searching Director Program Management jobs in Needham, MA look for? The top searched job categories for Director Program Management jobs in Needham, MA are:
What cities near Needham, MA are hiring for Director Program Management jobs? Cities near Needham, MA with the most Director Program Management job openings:
Director Program Management jobs near you
Infographic showing various Director Program Management job openings in Needham, MA as of August 2026, with employment types broken down into 79% Full Time, 16% Part Time, 2% Temporary, and 3% Contract. Highlights an 87% Physical, 2% Hybrid, and 11% Remote job distribution, with an average salary of $118,800 per year, or $57.1 per hour.

Senior Director, Program Lead

Deciphera Pharmaceuticals

Waltham, MA • On-site

$226K - $310K/yr

Full-time

Re-posted 4 days ago

Job description

Company Description
Job Description
Role Summary:
Deciphera's cross-functional program teams drive the strategy and operations of our late preclinical, clinical, and commercial assets. We are seeking a dynamic, seasoned Sr Director, Program Lead (PL) who will be responsible and accountable for one or more therapeutic assets. The successful candidate will be a strategic leader who can leverage their strong drug development expertise, EQ, and organizational skills to develop and drive the asset strategy and for leading all development and life-cycle management projects associated with the asset. Key attributes of the successful candidate include:
Key Responsibilities:
  • Program Strategy & Execution Accountability (60%)
    • For a given asset/program, responsible for the development and execution of the overarching global program strategy. The PL leads all research and development activities associated with an asset from approximately nomination of lead candidates to the marketplace with full accountability.
    • Drive the development and execution of the strategic plan, appropriately balancing data quality, timelines and costs based on current internal corporate considerations and the external landscape.
    • Lead one or more cross-functional program teams to define program vision, strategy, goals, decision points, investments and areas of risk and associated mitigations and contingencies.
    • Partners closely with the program manager to provide strategic, process and operational leadership to the Program team
    • Identifies and communicates risks and appropriate mitigations
    • Lead data-driven decision-making processes to enable timely and objective development decisions
  • Communicate (20%)
    • Holistic and confident communication: ensure PT clearly understands expectations from leadership, ensure leadership clearly understands program status, timelines, milestones, risks and mitigations
    • Focus team efforts on most critical tasks; identify and resolve communication bottlenecks
    • Participate in Portfolio Strategy Steering Committee meetings as the key representative of the program team
    • Liaise with relevant stakeholders within the Ono Pharma Group to ensure alignment across entities. Liaise with peers within the Program Leadership and Management function to maintain consistent cross-project standards, ensure aligned strategies, and to determine overlap of competing priorities.
  • Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively with other Deciphera PLs (20%)
    • PLs are experienced, versatile and strong enterprise leaders
    • PLs are highly collaborative cross-functional leaders who consistently drive top performance and deliver against challenging goals
    • PLs ensure that risks and challenges are addressed proactively and collaboratively with partner functions, with joint decision making when appropriate to drive, deliver and maximize asset value.
    • PLs are effective in communicating to partners and stakeholders at an appropriate level of detail.
  • Other duties and responsibilities as assigned.

Qualifications
Required Qualifications
  • A minimum of 15 years drug development experience in the biopharmaceutical industry including a minimum of 3 years' development program leadership experience
  • Solid understanding of drug development process (steps, functions and their roles, key interdependencies)
  • Strong interpersonal skills, with a proven track record of influencing without authority across a matrixed organization
  • Highly effective influencer without authority at all levels
  • Builds consensus, but identifies a final decision maker / escalates when required
  • Outstanding written and oral communicator, able to clearly and accurately express complex ideas
  • Demonstrated ability to be flexible and open to adjusting approaches as new information or circumstances emerge
  • Resilient in a fast-paced, rapidly evolving environment
  • Highly motivated with a "hands on" leadership style - no task is too big or small!
  • Strategic, efficient, organized, and empathetic leader who can zoom both in and out
  • Committed to driving the program forward to the next strategic inflection point to enable an informed decision for next steps, in line with corporate objectives.

Preferred Capabilities
  • Has experience managing cross functional teams
  • Late Phase/commercial experience a plus
  • Experience working with the Alliance and Business Development Teams and understanding the importance of partnerships
  • Experience with MS office suite (PowerPoint, Excel, MS Teams) required, project management tools (Smartsheet, ThinkCell, MS Project) a plus

Additional Information
Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $226,200 - $310,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.
Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera's competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.

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