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Director Program Management Jobs in Cambridge, MA

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Director Program Management information

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$35K

$119.2K

$200K

How much do director program management jobs pay per year?

As of Aug 16, 2026, the average yearly pay for director program management in Cambridge, MA is $119,194.00, according to ZipRecruiter salary data. Most workers in this role earn between $92,900.00 and $127,300.00 per year, depending on experience, location, and employer.

What does a director of program management do?

A Director of Program Management oversees multiple projects or programs within an organization, ensuring they align with the company's strategic goals. They are responsible for setting priorities, allocating resources, and managing teams of project managers. This role involves coordinating across departments, mitigating risks, and ensuring that programs are delivered on time and within budget. Directors of Program Management also communicate with executive leadership and stakeholders to report on progress and outcomes.

What are the key skills and qualifications needed to thrive as a director of program management?

To thrive as a Director of Program Management, you need extensive experience in program and project management, a relevant degree (often in business or engineering), and proven leadership abilities. Familiarity with tools like Microsoft Project, Jira, and portfolio management software, along with certifications such as PMP or PgMP, is typically required. Exceptional communication, strategic thinking, and stakeholder management skills distinguish top performers in this role. These skills ensure the effective delivery of complex initiatives, alignment with organizational goals, and strong cross-functional collaboration.

How does a director of program management typically collaborate with cross-functional teams to drive project success?

Directors of Program Management play a pivotal role in aligning cross-functional teams—such as engineering, product, marketing, and operations—to ensure that complex projects are delivered on time and within scope. They facilitate regular communication, resolve interdepartmental conflicts, and coordinate resources to keep everyone moving toward shared goals. This role often requires balancing strategic oversight with hands-on problem-solving, as well as fostering a collaborative culture that enables team members to contribute their expertise effectively. Strong relationship-building and negotiation skills are essential to proactively address challenges and maintain momentum across multiple initiatives.

What are the most commonly searched types of Program Management jobs in Cambridge, MA?

The most popular types of Program Management jobs in Cambridge, MA are:

What job categories do people searching Director Program Management jobs in Cambridge, MA look for?

The top searched job categories for Director Program Management jobs in Cambridge, MA are:

What cities near Cambridge, MA are hiring for Director Program Management jobs?

Cities near Cambridge, MA with the most Director Program Management job openings:

Director Program Management jobs near you
Infographic showing various Director Program Management job openings in Cambridge, MA as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 20% Part Time, and 2% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $119,194 per year, or $57.3 per hour.

Director, Program Management

Rhythm Pharmaceuticals

Boston, MA • On-site

$182K - $275K/yr

Full-time

Posted 3 days ago

New

Job description

Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
Rhythm is seeking an experienced and highly motivated Director, Program Management to join its program management team, reporting to the Head of Program Management. In this role, you will serve as a strategic partner and operational lead for one or multiple programs in different stages of development. You will be responsible for driving program strategy forward, developing and maintaining an integrated development plan, and holding program teams accountable for program execution. In addition, this role will have responsibility for cross-functional project management activities, serving as project management lead for operational excellence and continuous improvement defined projects. In this role, you will communicate and interface across all levels including executive leadership.
Responsibilities and Duties
  • Lead cross-functional execution of program strategy and operations to move one or more asset programs through the drug development lifecycle
  • Lead/Facilitate program core team meetings, develop agendas & communicate/track action items to completion
  • Develop and maintain integrated development plans, project timelines, risk logs, and integrated program budgets
  • Lead program core team/subteams in risk identification and mitigation, scenario planning, decision criteria, and milestone stage gates ensuring teams stay on track
  • Work with functional-area program leads to prioritize activities on critical path
  • Identify, communicate, and escalate program-wide interdependencies, issues, and key decisions to sr. leadership and appropriate forums
  • Serve as thought partner to head of program mgmt. through defining strategy, process, best practices and standardization
  • Ensure that cross-functional stakeholders and leaders are informed by clearly communicating updates within the program team and with leadership
  • Monitor potential budget, timeline and strategy variances; proactively bring forward with functions; assess options for tradeoffs within overall budget, timeline, and strategy
  • Coordinate development of impactful presentations to facilitate strategic planning and decision-making as well as preparing program status updates for Quarterly Portfolio Review meetings
  • Build relationships with key stakeholders to ensure alignment of corporate and functional objectives
  • Actively contribute to, oversee or lead the development of processes, tools, and standards necessary to establish program management best practices; Drive continuous process improvement initiatives across functional areas of Rhythm.

Qualifications and Skills
  • BA/BS degree or equivalent experience required
  • 10+ years of experience in pharma/biotech drug development with 5 years experience preferred in project/program management
  • Experience within clinical development/Phase 1 through regulatory submission strongly preferred
  • Passion and excitement for driving research forward toward a goal of helping patients with rare, unmet medical needs
  • Experience in rare disease indications preferred, but not required
  • Experience in both early and late phase development preferred including simultaneous oversight of multiple projects
  • Ability to drive strategic thinking and collaborate across multiple functions (Research, Development, Manufacturing, and Commercial)
  • Knowledge of pharmaceutical development, including regulatory approval pathways in US, Europe, ROW (IND, NDA, etc.)
  • Working knowledge of the essential activities for all key functional areas across cross-functional program teams
  • Exceptional planning and organizational skills and ability to execute while dealing with competing priorities
  • Excellent communication and interpersonal skills (written and verbal)
  • Proficient with MS Office Suite (Excel, Word and PowerPoint); Familiarity with Smartsheet or MS Project preferred

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.
The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.
More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.
At Rhythm our core values are:
  • We are committed to advancing scientific understanding to improve patients' lives
  • We are inspired to tackle tough challenges and have the courage to ask bold questions
  • We are eager to learn and adapt
  • We believe collaboration and ownership are foundational for our success
  • We value the unique contribution each individual brings to furthering our mission

Inherent in our core values is the commitment to act ethically and with integrity in all we do.
Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.
Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.

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