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Director Hpc System Engineer Jobs (NOW HIRING)

Altair Engineering

System Engineer - HPC

Troy, MI · On-site

Transforming the Future with the Convergence of Simulation and Data Systems Engineer - HPC Do you like a challenge, are you a complex thinker who likes to solve problems? If so, then you might be the ...

Meta

AI/HPC System Performance Engineer

Menlo Park, CA

$154K/yr

As an AI/HPC System Performance Engineer on the Network Infrastructure Engineering team, you will drive end-to-end performance characterization, bottleneck analysis, and optimization of large-scale ...

Power3 Solutions

Analyzes system requirements and leads design and development activities. Guides users in ... Provides system engineering services and support HPC System Design & Engineering organization in ...

Meta

AI/HPC System Performance Engineer

Menlo Park, CA · On-site

$154K - $217K/yr

As an AI/HPC System Performance Engineer on the Network Infrastructure Engineering team, you will drive end-to-end performance characterization, bottleneck analysis, and optimization of large-scale ...

BCT LLC

$197K - $214K/yr

Analyzes system requirements and leads design and development activities. Guides users in ... Provides system engineering services and supports the HPC System Design & Engineering organization ...

Prolim Global

CAE HPC System Administrator

Saline, MI · On-site

The ideal candidate combines strong Linux systems expertise, HPC workload management experience, and a solid understanding of CAE engineering environments. Key Responsibilities: * HPC Job Queuing ...

ExxonMobil

HPC Systems Engineer

Spring, TX

The HPC Systems Engineer will be involved in various aspects of designing and engineering our HPC ... Monitor overall system performance and health and partner with 3rd parties on hardware support as ...

ExxonMobil

HPC Systems Engineer

Spring, TX

The HPC Systems Engineer will be involved in various aspects of designing and engineering our HPC ... Monitor overall system performance and health and partner with 3rd parties on hardware support as ...

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All JobsDirector Hpc System Engineer Jobs

Director Hpc System Engineer information

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$53.5K

$127.2K

$167K

How much do director hpc system engineer jobs pay per year?

As of Jun 8, 2026, the average yearly pay for director hpc system engineer in the United States is $127,215.00, according to ZipRecruiter salary data. Most workers in this role earn between $98,000.00 and $157,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Director HPC System Engineer, and why are they important?

To thrive as a Director HPC System Engineer, you need deep expertise in high-performance computing architecture, system integration, and advanced problem-solving, usually supported by a degree in computer science or engineering. Familiarity with HPC cluster management tools, parallel computing frameworks, and certifications in relevant technologies like Linux or cloud platforms are highly valued. Strong leadership, project management, and communication skills help drive cross-functional teams and strategic initiatives. These abilities are crucial for optimizing complex computing environments and ensuring organizational objectives are met efficiently.

What does a Director HPC System Engineer do?

A Director HPC (High Performance Computing) System Engineer oversees the design, implementation, and management of high-performance computing systems within an organization. They lead teams responsible for deploying and maintaining scalable computing infrastructures that support advanced scientific research, data analysis, and complex computational tasks. This role typically involves strategic planning, collaborating with stakeholders, ensuring system security and performance, and staying updated with the latest HPC technologies. Directors also mentor engineering staff and help set the vision for future HPC initiatives.

What are some common challenges faced by a Director HPC System Engineer when managing large-scale computing infrastructure?

As a Director HPC System Engineer, one of the main challenges involves ensuring the reliability and scalability of complex, high-performance computing environments while balancing resource allocation and budget constraints. Managing a diverse team of engineers, coordinating with researchers or end-users, and keeping up with rapidly evolving HPC technologies are also frequent hurdles. Additionally, optimizing system performance, troubleshooting bottlenecks, and overseeing regular maintenance and security updates are part of the daily responsibilities. Successfully navigating these challenges requires strong leadership, technical expertise, and effective communication across multidisciplinary teams.

What is the difference between Director Hpc System Engineer vs Hpc System Engineer?

AspectDirector Hpc System EngineerHpc System Engineer
CredentialsBachelor's/Master's in Computer Science or related, certifications like HPC certificationsBachelor's in Computer Science or related, similar certifications
Work EnvironmentLeadership role overseeing teams, strategic planningTechnical role focusing on system setup and maintenance
Employer & IndustryResearch institutions, large tech companies, data centersResearch labs, universities, tech firms

The main difference is that the Director Hpc System Engineer holds a leadership position responsible for strategic planning and team management, while the Hpc System Engineer focuses on technical system implementation and maintenance. The director role involves higher-level decision-making, whereas the engineer role is more hands-on technical work.

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Director Hpc System Engineer jobs near you
Infographic showing various Director Hpc System Engineer job openings in the United States as of May 2026, with employment types broken down into 1% Locum Tenens, 1% As Needed, 96% Full Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $127,215 per year, or $61.2 per hour.
Director, HPC Infrastructure Engineering

Director, HPC Infrastructure Engineering

Guardant Health

Palo Alto, CA • On-site

$126K - $165K/yr

Full-time

Posted 19 days ago

Job description

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visitguardanthealth.comand follow the company onLinkedIn,X (Twitter)andFacebook.

Guardant Health's High-Performance Computing team (HPC) builds and operates the computational technology infrastructure backbone of the company.

This includes scalable data storage that holds petabytes of genomics data, high performance compute clusters running a custom bioinformatics pipeline in production and R&D environments, and the softwareinfrastructurethat hosts an ecosystem of services for internal data processing and external data integration.To facilitateGuardantHealth's fast growth in the next few years, the HPC team is seeking a strong technical engineering leader who can help maintain and grow the HPC infrastructure during its expansion, while partnering with other engineering functions (Corporate IT, SQA and DevOps/SRE) as well as the R&D user community and Lab Operations. This is a hands-on technical leadership position that will leverage your expertise in HPC environments, as well as your experience leading and managing a team.

Role: Director, HPC Infrastructure Engineering

Location: Preference is given to candidates located in the San Francisco Bay Area with the ability to work onsite in Redwood City and Palo Alto; however, the role offers partial remote flexibility.

Onsite presence is required during rotational coverage, scheduled maintenance windows, and cluster deployment activities.

In this role, you will primarily lead an engineering team to:

  • Oversee and manage the HPC environment - compute, storage, network, physical infrastructure, and software - serving multiple Production and Development clusters
  • Integrate HPC systems with on-prem and cloud-based systems and data sources as required
  • Administer multiple HPC clusters and associated cluster file systems
  • Research, design, and implement next-generation HPC solutions
  • Diagnose and resolve production system stack issues, leveraging software utilities down to the source code level (e.g., shell scripts, Python, etc.)
  • Maintain and monitor infrastructure and facilities to ensure operational stability
  • Drive continuous improvement initiatives to enhance reliability and performance as workloads and data volumes scale
  • Ensure control, integrity, and accessibility across systems and applications serving multiple concurrent users
  • Provide operational oversight for systems at remote and international locations
  • Collaborate with offsite consultants to sustain and optimize infrastructure performance
  • Partner with vendors to procure, troubleshoot, upgrade, repair, and replace systems as needed
  • Foster a culture of continuous engineering improvement through design and architecture review, mentoring, feedback, and development and monitoring of key performance metrics
  • Hire, coach, and mentor individuals; build a strong cross-functional organization
  • Partner with a diverse customer base to understand requirements, priorities, and processes
  • Propose and implement new projects or recommend system improvements
  • Observe Quality standards appropriate for an FDA governed and CLIA/CAP compliant diagnostic laboratory
  • Manage budgets to balance refresh of obsolete equipment and software, scaling to support company growth, utilizing fixed headcount and contractor/consulting resources
  • Participate in a 24/7 on-call rotation

Required:

  • B.S. in Computer Science or related technical field or equivalent experience
  • 10 years' experience with high performance computing platforms, preferably organizations handling large volumes of sequenced genomic data, within a commercial enterprise
  • Experience with software-defined Infrastructure and cloud computing - Google Cloud Platform, Amazon Web Service (AWS) etc
  • GPUs and Petabyte scale Storage platforms management experience
  • Design, deployment, support and troubleshooting experience, in a complex computing environment
  • HPC Engineering team management experience (either directly or in a matrixed environment)
  • 4+ years of networking experience with certification of CCNA or better
  • 4+ years of Linux/Unix system administration, knowledge of Unix network protocols, TCP/IP, coreinfrastructuretechnologies and virtualization
  • 2+ years of large-scale data storage and compute clusters (HPC)infrastructure
  • 2+ years working in and with on-premise and cloud-based (AWS, Google, IBM and Azure) data-centers
  • 2+ years of building software release and ops processes and automation toolset
  • 2+ years providing documentation of system administration

Preferred:

  • Proficiency with Arista and compatible networking, up to and including 400 Gb/s links
  • Hands-on administration of IBM's General Parallel File System
  • Operational oversight of Slurm scheduler
  • Working knowledge of cloud bursting technologies
  • Familiarity with wide area file systems
  • Practical expertise in Docker and container technologies
  • Working experience with Kubernetes
  • Operation of infrastructure compliant with HIPAA and SOX standards

Success Profile:

  • Excels in agile, high-velocity technical environments.
  • Demonstrates self-leadership and a commitment to advancing both individual and team expertise.
  • Combines engineering rigor with pragmatic adaptability.
  • Successfully manages operational SLAs while leading initiatives critical to business growth.


Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate's compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $230,200 - $316,600 Other US Location(s) Base Pay Range: $195,700 - $269,100 If the role is performed in Colorado, the pay range for this job is: $207,200 - $284,950


Employee may be required to lift routine office supplies and use office equipment.Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment.Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out toPeopleteam@guardanthealth.com

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review ourPrivacy Notice for Job Applicants.

Please visit our career page at:http://www.guardanthealth.com/jobs/

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