Director Commercial Operation Jobs (NOW HIRING)

Osteal Therapeutics is a Dallas-based, privately held biotechnology company redefining the standard of care for life-altering orthopedic infections.

Osteal is hiring to launch NEXCHANGE™ KIT, a first-of-its-kind FDA Breakthrough Therapy for periprosthetic joint infection (PJI), a critical condition impacting 50,000 Americans annually. PJI currently lacks FDA-approved therapies and forces patients through grueling, months-long treatments with poor outcomes. Our disruptive technology transforms this journey by safely delivering high-concentration, broad-spectrum antibiotics directly to the infection site; reducing the treatment timeline from months to just seven days.

Powered by $137M in funding to date and a distinguished investor base that includes strategic partners Johnson & Johnson and Zimmer Biomet, we are advancing toward FDA approval and building the organization that will bring this therapy to patients in dire need.

We are looking for bold, relentless professionals who thrive in a “builder” environment. If you are driven by the opportunity to do work that genuinely matters—to be part of a cohesive and capable team striving to deliver the first on‑label PJI treatment that promises to transform outcomes for tens of thousands of patients.

The Commercial Operations Director will play a central role in ensuring the effective and efficient delivery of a potentially groundbreaking targeted infection therapy for musculoskeletal infections. This position will have responsibility for supporting the commercial organization in the design, development, and maintenance of programs, processes, tools, and practices. The role will have responsibility building out and maintaining the commercial systems required for commercialization. It will also be responsible for execution of sales planning and operations, data analytics and insights, and reporting. The Commercial Operations Director will manage, generate, interpret, and communicate insights driven analytics across all commercial functions with responsibility for developing dashboards to track key performance indicators (KPI).

• Technology
  • Collaborate with Commercial stakeholders to design, deliver and maintain technology solutions that align to Commercial’s business strategic direction.
  • Design, develop, implement and lead the company's customer management system (CRM) with input from Commercial, IT, Quality and Finance.
  • Support the build, implementation, and maintenance of sales tools, including CRM, data analytics, and sales dashboards.
  • Lead the development of databases and infrastructure to support analytics, insights, forecasting and budgeting.
• Data Analytics & Reporting
  • Work with cross‑functional team members to identify and prioritize actionable, high‑impact insights across a variety of core business areas including Sales, Marketing, Finance and Market Access.
  • Oversee market insights, analytics and competitive intelligence to deliver data driven business recommendations.
  • Research, design, implement, and validate cutting‑edge dashboards to analyze diverse sources of data to achieve targeted outcomes.
  • Institute processes for data and reporting governance of ad‑hoc field‑based inquiries from the Executive Leadership Team and other Commercial functions.
  • Lead data inquiry and data stewardship efforts in support of field‑based teams.
• Field Management
  • Strategic and tactical planning for field teams including management of vehicle allowance, incentive compensation design and administration, data management, reporting, and CRM management.
  • Oversee field effectiveness and operations, including territory planning, sales performance tracking and analytics, incentive programming, and the development and delivery of customer engagement and sales enablement tools.
  • Design, develop, implement and manage an integrated Case Management utility to ensure efficient coordination of NexChange procedure.
• Budget & Forecast Management
  • Develop and oversee the operational budget, ensuring efficient allocation of resources and monitoring of key performance indicators (KPIs) to drive cost reduction and service improvement.
  • Work closely with Commercial and Finance to ensure accurate forecasting reporting.
• Trade & Distribution
  • Develop a deep knowledge of the channel strategy along with standard of care fluency to support case logistics in the field by ensuring drug, device and representative readiness.
  • Support the head of trade and distribution with data, reporting, and inventory management.
• Launch Readiness
  • Lead cross‑functional launch readiness meetings, track risks, and manage cross‑functional partners.
  • Closely collaborate with leadership and support strategic cross-functional initiatives.
  • Drive operational alignment, enablement, execution excellence and continuous improvement of commercial operations.

• Bachelor’s degree required; advanced degree (MBA or related discipline) preferred.
• 10+ years of progressive commercial operations experience within biotechnology, pharmaceuticals, medical devices, or combination product organizations.
• Prior launch experience supporting specialty products, hospital‑based therapies, or complex reimbursement environments.
• Demonstrated success building commercial infrastructure and operational processes within emerging or high‑growth companies.
• Experience supporting market access, reimbursement, and contracting operations.
• Strong analytical and strategic planning capabilities with experience leveraging commercial data to drive business decisions.
• Experience with CRM systems, commercial analytics platforms, and sales operations tools.
• Exceptional cross‑functional leadership, communication, and organizational skills.
• Ability to thrive in a fast‑paced, hands‑on start‑up environment with evolving priorities.
• Willingness to travel as needed.

• 100% of Health Insurance paid by Osteal Tx for Employee & Dependents
• Dental & Vision Insurance
• Short & Long Term Disability Insurance paid 100% by Osteal Tx
• 401(k) (Regular & Roth)
• Holiday Pay & PTO
• Competitive compensation: ($220,000 - $260,000) + Bonus + Equity

Osteal Therapeutics is an Equal Opportunity Employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to protected characteristics such as race, color, religion, sex, national origin, age, disability or veteran status.