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How much do day shift upstream manufacturing associate jobs pay per hour?

As of Jun 7, 2026, the average hourly pay for day shift upstream manufacturing associate in the United States is $20.84, according to ZipRecruiter salary data. Most workers in this role earn between $16.35 and $23.32 per hour, depending on experience, location, and employer.

What is a Day Shift Upstream Manufacturing Associate?

A Day Shift Upstream Manufacturing Associate is responsible for preparing and operating equipment to support the initial stages of biopharmaceutical production, typically involving cell culture, fermentation, and media preparation. Working during the day shift, they monitor processes, maintain sterile environments, and ensure production runs smoothly and efficiently. Their work is crucial in ensuring quality and consistency in the early phases of manufacturing biological products such as vaccines or therapeutic proteins.

What is the difference between Day Shift Upstream Manufacturing Associate vs Night Shift Upstream Manufacturing Associate?

AspectDay Shift Upstream Manufacturing AssociateNight Shift Upstream Manufacturing Associate
Work HoursTypically 8 AM - 4 PMTypically 8 PM - 4 AM
Work EnvironmentManufacturing floor during daytime operationsManufacturing floor during nighttime operations
Required SkillsSimilar technical skills, safety protocols, and certificationsSame technical skills, safety protocols, and certifications
Employer UsageCommonly used in biopharma and biotech manufacturingSame industry usage, different shift timing

The main difference between a Day Shift Upstream Manufacturing Associate and a Night Shift Upstream Manufacturing Associate lies in their working hours. Both roles require similar skills, certifications, and work environments, but they operate during different shifts. Employers in biopharma and biotech industries often employ both to ensure continuous production, with shift timing being the primary distinction.

What are the typical collaboration points between a Day Shift Upstream Manufacturing Associate and other teams in a biomanufacturing facility?

Day Shift Upstream Manufacturing Associates frequently collaborate with downstream processing teams, quality control, and process engineering staff. Daily responsibilities often involve communicating batch progress, troubleshooting issues, and ensuring compliance with safety and GMP standards. Clear documentation and timely reporting to supervisors and quality teams are crucial for maintaining production flow. This cross-functional teamwork ensures efficient handoffs and rapid response to any process deviations, making collaboration a key part of the role.

What are the key skills and qualifications needed to thrive as a Day Shift Upstream Manufacturing Associate, and why are they important?

To excel as a Day Shift Upstream Manufacturing Associate, you typically need a background in biotechnology or life sciences, experience with aseptic techniques, and an understanding of Good Manufacturing Practices (GMP). Familiarity with bioreactors, cell culture systems, and process control software is commonly required, along with relevant safety or GMP certifications. Attention to detail, teamwork, and strong problem-solving abilities are valuable soft skills in this role. These competencies ensure the efficient and compliant production of high-quality biopharmaceuticals in a regulated manufacturing environment.
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Day Shift Upstream Manufacturing Associate jobs near you
Infographic showing various Day Shift Upstream Manufacturing Associate job openings in the United States as of May 2026, with employment types broken down into 1% Locum Tenens, 84% Full Time, and 15% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $43,341 per year, or $20.8 per hour.
Manufacturing Associate - Biotech - Vacaville, CA

Manufacturing Associate - Biotech - Vacaville, CA

Unicon Pharma Inc.

Vacaville, CA • On-site

Contractor

Posted 4 days ago

Job description

Description:
Shifts and Hours schedule:
Upstream Day Shift: 6am - 7pm
Upstream Night Shift: 6pm - 7am
Downstream Day Shift: 6:30am - 7:30pm
Downstream Night Shift: 6:30pm - 7:30am
  • These roles follow a 3-4-3 shift pattern

Role Purpose:

  • The Manufacturing Associate is responsible for the manufacture of therapeutic proteins (API) under cGMP conditions.
  • Level I associates are expected to execute process recipes, follow written procedures (SOPs), monitor equipment and processes, perform basic laboratory tasks, including pH, conductivity, sampling, and conduct routine sanitization tasks to maintain facility and equipment.
  • They are expected to attain a basic understanding of cGMP compliance while training under close supervision, demonstrating aseptic technique in handling of products and materials.
  • 40% Set up, operate equipment, and monitor production processes, including clean-in-place (CIP) and steam-in-place (SIP) operations and report production in written and electronic documents in accordance with good manufacturing practice (GMPs) and good documentation procedures (GDPs), review documentation as appropriate
  • 20% Attain qualification for all assigned tasks and maintain individual training plan
  • 10% Perform basic laboratory tasks, such as monitor pH, conductivity, test product samples, etc.
  • 10% Perform material movements, transfer raw materials, chemicals into, out of, across the production areas.
  • 10% Maintain facility and equipment through routine cleaning and sanitization, support 6S programs
  • 10% Administrative tasks – attending shift exchange, meetings, sending/receiving emails, participating in projects, perform other duties as assigned.
  • High School Diploma or Equivalent minimum; AS/BS preferred
  • Preferred area of study: Science related discipline
  • 0-3 years’ experience; some prior experience in a manufacturing setting preferred.
  • Proven logic and decision making abilities, critical thinking skills