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Day Shift Upstream Manufacturing Associate Jobs in Raleigh, NC

As a leading developer, manufacturer, and global supplier of scientific laboratory products for 100 ... Relieve other Production Associates during their absence or break periods, and for rotation of ...

Manufacturing Associate This role involves setting up and maintaining multiple CNC machines in a ... shift and be available for substantial overtime, including working most days of the week. * Support ...

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Day Shift Upstream Manufacturing Associate information

See Raleigh, NC salary details

$11

$20

$32

How much do day shift upstream manufacturing associate jobs pay per hour?

As of Sep 7, 2026, the average hourly pay for day shift upstream manufacturing associate in Raleigh, NC is $20.26, according to ZipRecruiter salary data. Most workers in this role earn between $15.87 and $22.64 per hour, depending on experience, location, and employer.

What is a day shift upstream manufacturing associate?

A Day Shift Upstream Manufacturing Associate is responsible for preparing and operating equipment to support the initial stages of biopharmaceutical production, typically involving cell culture, fermentation, and media preparation. Working during the day shift, they monitor processes, maintain sterile environments, and ensure production runs smoothly and efficiently. Their work is crucial in ensuring quality and consistency in the early phases of manufacturing biological products such as vaccines or therapeutic proteins.

What are the key skills and qualifications needed to thrive as a day shift upstream manufacturing associate?

To excel as a Day Shift Upstream Manufacturing Associate, you typically need a background in biotechnology or life sciences, experience with aseptic techniques, and an understanding of Good Manufacturing Practices (GMP). Familiarity with bioreactors, cell culture systems, and process control software is commonly required, along with relevant safety or GMP certifications. Attention to detail, teamwork, and strong problem-solving abilities are valuable soft skills in this role. These competencies ensure the efficient and compliant production of high-quality biopharmaceuticals in a regulated manufacturing environment.

What are the typical collaboration points between a day shift upstream manufacturing associate and other teams in a biomanufacturing facility?

Day Shift Upstream Manufacturing Associates frequently collaborate with downstream processing teams, quality control, and process engineering staff. Daily responsibilities often involve communicating batch progress, troubleshooting issues, and ensuring compliance with safety and GMP standards. Clear documentation and timely reporting to supervisors and quality teams are crucial for maintaining production flow. This cross-functional teamwork ensures efficient handoffs and rapid response to any process deviations, making collaboration a key part of the role.

What is the difference between Day Shift Upstream Manufacturing Associate vs Night Shift Upstream Manufacturing Associate?

AspectDay Shift Upstream Manufacturing AssociateNight Shift Upstream Manufacturing Associate
Work HoursTypically 8 AM - 4 PMTypically 8 PM - 4 AM
Work EnvironmentManufacturing floor during daytime operationsManufacturing floor during nighttime operations
Required SkillsSimilar technical skills, safety protocols, and certificationsSame technical skills, safety protocols, and certifications
Employer UsageCommonly used in biopharma and biotech manufacturingSame industry usage, different shift timing

The main difference between a Day Shift Upstream Manufacturing Associate and a Night Shift Upstream Manufacturing Associate lies in their working hours. Both roles require similar skills, certifications, and work environments, but they operate during different shifts. Employers in biopharma and biotech industries often employ both to ensure continuous production, with shift timing being the primary distinction.

What cities near Raleigh, NC are hiring for Day Shift Upstream Manufacturing Associate jobs?

Cities near Raleigh, NC with the most Day Shift Upstream Manufacturing Associate job openings:

Infographic showing various Day Shift Upstream Manufacturing Associate job openings in Raleigh, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $42,131 per year, or $20.3 per hour.

Manufacturing Associate, Bulk Drug Substance Upstream - Days

Amgen, Inc.

Holly Springs, NC โ€ข On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 8 days ago


Job description

Career Category
Manufacturing
Job Description
HOW MIGHT YOU DEFY IMAGINATION?
You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX Batch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Manufacturing Associate, Bulk Drug Substance Upstream - Days
Live
What you will do
Let's do this! Let's change the world! In this dynamic role, you will be an Associate in the manufacturing organization at Amgen North Carolina (ANC). The schedule is a rotating 2-2-3, 5:45AM-6:15PM (12-hour shift). Associates will be completing operations on the floor in our upstream area and are responsible for the manufacturing of cGMP (Current Good Manufacturing Practices) drug substance.
With general direction, the Associate will support all floor operations in accordance with cGMP practices.
Responsibilities will include...
Compliance:
  • Completes work in accordance with established cGMP procedures and policies (Standard Operating Procedures [SOPs], Manufacturing Procedures [MPs], Job Hazard Analysis [JHAs], Code of Federal Regulations [CFR]) with strict adherence to safety and compliance

  • Assure proper gowning and aseptic techniques are always followed

Process/Equipment/Facilities:
  • Perform hands-on operations including set-up, cleaning, sanitization, monitoring of equipment and assigned area

  • Run and monitor critical process tasks per assigned procedures

  • Perform in-process sampling, operate analytical equipment, and complete process documentation (Electronic Batch Records [EBRs])

  • Identify and escalate issues and concerns regarding daily routine functions related to process and tasks; may engage with team on potential solutions

  • Perform documentation for assigned functions (i.e., equipment logs, EBRs)

  • Collaborate as part of a cross-functional team (i.e., QA/QC, F&E (Facilities & Engineering), PPIC, Mfg., PD (Process Development), Regulatory, etc.) in completing production activities

  • Maintain an organized, clean, and workable space

Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The hard-working professionals we seek are team players with these qualifications.
Basic Qualifications:
  • High School/GED + 2 years manufacturing and/or other regulated environment experience

Or
  • Associate's Degree + 6 months manufacturing and/or other regulated environment experience

Or
  • Bachelor's Degree

Preferred Qualifications:
  • Completion of NC BioWorks Certification Program

  • Experience in a regulated industry such as biotechnology or pharmaceutical

  • Basic understanding and process experience in a cGMP manufacturing facility

  • Excellent verbal and written communication

  • Proficient Microsoft Office skills, and knowledge of other electronic systems such as EBR/MES, Delta V, and Electronic Quality Systems

  • An ability to demonstrate desire and drive to learn and grow their understanding of operations and processes

Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
#AmgenNorthCarolina
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Salary Range
70,985.20USD -96,038.80 USD