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Cra Ii Jobs (NOW HIRING)

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

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CRA II and Senior CRA

Downers Grove, IL · Remote

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

System One

CRA II

Exton, PA · Remote

$82K - $107K/yr

CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model:

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CRA II and Senior CRA

Lawrence, KS · Remote

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

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CRA II and Senior CRA

Salt Lake City, UT · Remote

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

ICON

CRA II and Senior CRA

Downers Grove, IL · On-site

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

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CRA II and Senior CRA

Houston, TX · Remote

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

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CRA II and Senior CRA

Portland, OR · Remote

$91K - $114K/yr

CRA II or Senior CRA (Home-based in U.S.) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

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CRA 2

Blue Bell, PA · On-site

As a CRA II at ICON, you will design and analyse clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies. What You Will Do: You ...

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All JobsCra Ii Jobs

Cra Ii information

See salary details

$12

$41

$69

How much do cra ii jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for cra ii in the United States is $41.13, according to ZipRecruiter salary data. Most workers in this role earn between $28.85 and $52.64 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Clinical Research Associate II (CRA II), and why are they important?

To thrive as a CRA II, you need a solid background in clinical research, knowledge of Good Clinical Practice (GCP), and typically a bachelor's degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and clinical trial management software is essential. Strong attention to detail, organizational skills, and effective communication help build trust with study sites and ensure protocol adherence. These competencies are crucial for maintaining data integrity, regulatory compliance, and the overall success of clinical trials.

What are some common challenges CRA IIs face when managing multiple clinical trial sites simultaneously?

As a CRA II, juggling several clinical trial sites can present challenges such as coordinating site visits, maintaining timely communication, and ensuring protocol compliance across diverse teams. Effective time management, organization, and proactive problem-solving are essential to address site-specific issues and keep studies on track. Additionally, balancing travel demands with documentation and reporting requirements can be demanding, so strong prioritization and adaptability are key for success in this role.

What is the difference between Cra Ii vs Cra I?

AspectCra ICra II
Required CertificationsTypically requires a basic certification or no certificationRequires advanced certification or more experience
Work EnvironmentEntry-level clinical research settingsMore complex projects, increased responsibilities
Job ResponsibilitiesAssisting with data collection and basic tasksOverseeing data, coordinating activities, mentoring Cra I
Industry UsageCommonly used in clinical research organizations and pharmaUsed in similar settings but with higher responsibility

The main difference between Cra I and Cra II lies in experience, responsibilities, and certifications. Cra II roles involve more complex tasks, greater oversight, and often require additional certifications, reflecting a higher level of expertise in clinical research.

What is a CRA II?

CRA II stands for Clinical Research Associate II. These professionals are responsible for monitoring clinical trials to ensure compliance with regulatory requirements and study protocols. They serve as a key link between the clinical trial site and the sponsor or CRO, overseeing data integrity, patient safety, and proper documentation. CRA IIs typically have more experience than entry-level CRAs and may handle more complex trials or sites.
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What states have the most Cra Ii jobs?

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Cra Ii jobs near you
Infographic showing various Cra Ii job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 5% Part Time, 1% Temporary, and 2% Contract. Highlights an 81% Physical, 6% Hybrid, and 13% Remote job distribution, with an average salary of $85,542 per year, or $41.1 per hour.

CRA II

System One

Exton, PA • Remote

$82K - $107K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 28 days ago

Job description

Job Title: CRA II Location: Must be Mid-West based in the United States Type: Direct Hire, full time permanent direct with the client Salary Range: $82,000 - $107,000 commemorate with level of experience Model: Hybrid – onsite and remote Hours: 40.0 Looking for your next step as a CRA? This is an opportunity to join a fast-moving medical device organization where you'll have meaningful ownership, strong visibility within Clinical Operations, and the ability to contribute to studies that can directly impact patient outcomes.

Responsibilities

  • Maintain TMF and regulatory documentation ensuring ICH/GCP and SOP compliance; oversee IRB approvals, informed consent quality, investigational device accountability, and complete/accurate reporting of AEs and protocol-required data.
  • Support study start-up and site readiness, conduct site training, manage study supplies and tracking systems, resolve queries/DCFs, and identify/implement corrective actions for protocol deviations across multiple concurrent studies.
  • Drive communication through team meetings, status reporting, and milestone tracking; support audits and site payments, lead documentation updates, and contribute to SOP enhancements and operational best practices.
Requirements
  • Bachelor’s Degree, or RN required
  • 2+ years monitoring experience
  • 3+ Clinical Research Coordinator experience
  • Class III Medical Device experience required
  • ICU (and therefore hospital) and site management experience required
  • Ability to travel 2-4 times/month (depends on volume of need)

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

#M- #LI- #LI-ES1 Ref: #568-Clinical