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Computer System Validation Manager Jobs in Pennsylvania

Compli

CSV Lead/ Computer System Validation Lead

Marietta, PA · On-site

$96K - $127K/yr

CSV Lead/ Computer System Validation Lead Location : Marietta, PA Compli, LLC was founded in 2001 to provide Commissioning, Validation and Regulatory Support Services to the Life Sciences industry.

Valspec

Equipment Validation Engineer

Royersford, PA · On-site

... a team that also includes computer system validation engineers and specialists. Key ... Ability to work independently and manage multiple priorities. This is an excellent opportunity for ...

Novocure

Digital Systems Validation Lead

Wayne, PA · On-site

$116K - $130K/yr

Master's degree preferred * 8+ years of experience in computer system validation within regulated ... Leadership experience managing and developing validation teams, governance frameworks, and scalable ...

Novocure

Digital Systems Validation Lead

Wayne, PA · Hybrid

$116K - $130K/yr

Master's degree preferred * 8+ years of experience in computer system validation within regulated ... Leadership experience managing and developing validation teams, governance frameworks, and scalable ...

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All JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Pennsylvania

Computer System Validation Manager information

See Pennsylvania salary details

$47.6K

$105.7K

$160.9K

How much do computer system validation manager jobs pay per year?

As of Jun 24, 2026, the average yearly pay for computer system validation manager in Pennsylvania is $105,668.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $132,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Computer System Validation Manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a Computer System Validation Manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a Computer System Validation Manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are the most commonly searched types of Computer System Validation jobs in Pennsylvania? The most popular types of Computer System Validation jobs in Pennsylvania are:
What are popular job titles related to Computer System Validation Manager jobs in Pennsylvania? For Computer System Validation Manager jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Pennsylvania look for? The top searched job categories for Computer System Validation Manager jobs in Pennsylvania are:
What cities in Pennsylvania are hiring for Computer System Validation Manager jobs? Cities in Pennsylvania with the most Computer System Validation Manager job openings:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Pennsylvania as of June 2026, with employment types broken down into 2% Locum Tenens, 5% As Needed, 69% Full Time, 9% Part Time, 12% Contract, and 3% Nights. Highlights an 89% Physical, 5% Hybrid, and 6% Remote job distribution, with an average salary of $105,668 per year, or $50.8 per hour.
CSV Lead - Computer System Validation

CSV Lead - Computer System Validation

Centstone

Lancaster, PA • On-site

Full-time

Posted 12 days ago

Job description

Job Title: CSV Lead – Computer System Validation
Location: Lancaster, PA
Experience: 1O–20 Years
Job Type: Long-Term Contract
Work Model: Onsite

Job Summary:
Seeking an experienced CSV Lead to support Computer System Validation activities for a newly constructed Sterile Drug Product Clinical Manufacturing facility. The role involves leading CSV strategy, validation documentation, and execution activities in a GMP-regulated pharmaceutical environment.

Key Skills:

  • Computer System Validation (CSV)

  • AVEVA System Platform & PI Historian

  • Allen Bradley & Siemens PLC

  • SCADA, HMI, OIT Platforms

  • Operational Technology (OT)

  • Instrumentation & Control Systems

  • Alarm Management Systems

  • Robotic Isolators & Lyophilization

  • Autoclave & Equipment Wash Systems

  • Kneat Experience Preferred

Requirements:

  • 10–20 years of CSV experience in Pharma/Biotech

  • Strong GMP/GxP validation knowledge

  • Ability to work independently in fast-paced project environment

  • Excellent communication and deviation management skills

Thanks 

Adarsh Mallik

CENTSTONE LLC

adarsh.mallik@centstone.com

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About Centstone

Sourced by ZipRecruiter

In the dynamic landscape of today’s business environment, flexibility is key. At Centstone, we understand the unique demands of your industry and offer tailored Contract Hiring solutions to empower your organization with the right talent when you need it most.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Hazlet, NJ, US

Year founded

2022

Social media

Facebook

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