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Computer System Validation Manager Jobs in Pennsylvania

Deloitte

System Test and Validation Lead

Pittsburgh, PA · On-site +1

This role supports system validation strategy, audit readiness, CAPA management, and risk-based ... Bachelor's degree in business, information systems, computer science, engineering, or equivalent ...

Deloitte

System Test and Validation Lead

Pittsburgh, PA · On-site +1

This role supports system validation strategy, audit readiness, CAPA management, and risk-based ... Bachelor's degree in business, information systems, computer science, engineering, or equivalent ...

Deloitte

System Test and Validation Lead

Pittsburgh, PA · On-site +1

This role supports system validation strategy, audit readiness, CAPA management, and risk-based ... Bachelor's degree in business, information systems, computer science, engineering, or equivalent ...

GSK

Senior Validation Engineer

King Of Prussia, PA · On-site

Development of procedures, practices, and policies related to computer system validation. Monitor ... Lean Management, Problem Solving, Project Management, Quality Assurance (QA), Risk Awareness ...

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All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Pennsylvania

Computer System Validation Manager information

See Pennsylvania salary details

$47.6K

$105.7K

$160.9K

How much do computer system validation manager jobs pay per year?

As of Aug 25, 2026, the average yearly pay for computer system validation manager in Pennsylvania is $105,668.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $132,300.00 per year, depending on experience, location, and employer.

What does a computer system validation manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What are the key skills and qualifications needed to thrive as a computer system validation manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a computer system validation manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are the most commonly searched types of Computer System Validation jobs in Pennsylvania?

The most popular types of Computer System Validation jobs in Pennsylvania are:

What are popular job titles related to Computer System Validation Manager jobs in Pennsylvania?

For Computer System Validation Manager jobs in Pennsylvania, the most frequently searched job titles are:

What job categories do people searching Computer System Validation Manager jobs in Pennsylvania look for?

The top searched job categories for Computer System Validation Manager jobs in Pennsylvania are:

What cities in Pennsylvania are hiring for Computer System Validation Manager jobs?

Cities in Pennsylvania with the most Computer System Validation Manager job openings:

Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Pennsylvania as of August 2026, with employment types broken down into 73% Full Time, 13% Part Time, and 14% Contract. Highlights an 86% In-person, 5% Hybrid, and 9% Remote job distribution, with an average salary of $105,668 per year, or $50.8 per hour.

Senior Clinical Computer System Validation Engineer

Blue Bell, PA • On-site

Icon plc
See more jobs at Icon plcexternal

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 12 days ago

Job description

Senior Clinical Computer System Validation Engineer

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


We are seeking an experienced CSV Quality Consultant to support a strategic software integration program within a regulated pharmaceutical environment.

The consultant will provide quality and validation expertise throughout the lifecycle of computerized systems, ensuring compliance with GxP requirements, data integrity principles, and company quality standards.

What You Will Do:

You will take ownership of software development and engineering deliverables, applying your expertise to complex challenges.
Key responsibilities include:

  • Support the validation lifecycle of computerized systems in accordance with GAMP 5, CSA, and internal quality procedures.

  • Provide quality oversight for software implementation, integration, and data migration activities.

  • Develop and review validation deliverables, validation plans, risk assessments, requirements traceability matrices, test protocols, summary reports, and change controls.

  • Ensure migration and integration activities maintain data integrity, traceability, and regulatory compliance.

  • Partner with business, IT, data, and quality stakeholders to support project delivery and inspection readiness.

  • Review vendor documentation and assess supplier validation approaches.

  • Lead or support computerized system retirement and decommissioning activities, including archival, data retention, and preservation of validation evidence.

  • Identify compliance risks and recommend pragmatic, risk-based solutions.

Your Profile:

  • Bachelor's degree in Life Sciences, Computer Science, Engineering, Information Technology, or a related discipline.

  • Minimum 10 years of experience in Computerized System Validation (CSV) within the pharmaceutical, biotechnology, or medical device industry.

  • Strong knowledge of GxP, GAMP 5, CSA, 21 CFR Part 11, Annex 11, and data integrity principles (ALCOA+).

  • Proven experience supporting system implementations, integrations, and data migration projects.

  • Experience with system decommissioning, archival, and record retention requirements.

  • Excellent stakeholder management, communication, and problem-solving skills.

  • Demonstrated ability to work in cross-functional and global project teams.


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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