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Computer System Validation Manager Jobs in Pennsylvania

Innovcentric LLC

CSV Lead

King Of Prussia, PA · On-site

$65/hr

King of Prussia, PA Mode (TP/FTE) TP Mandatory Skills Computer System Validation, Computed system assurance, GAMP,GxP risk assessments,Change Management JD 12+ years' Experience in Validating systems ...

Valspec

Validation Engineer (CQV)

Collegeville, PA

Validation Engineer (CQV) Location: Raleigh-Durham area, NC Position Overview We are seeking an ... Ability to manage multiple systems and priorities during commissioning/startup phases Work ...

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All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Pennsylvania

Computer System Validation Manager information

See Pennsylvania salary details

$47.6K

$105.7K

$160.9K

How much do computer system validation manager jobs pay per year?

As of Jul 15, 2026, the average yearly pay for computer system validation manager in Pennsylvania is $105,668.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $132,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Computer System Validation Manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a Computer System Validation Manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a Computer System Validation Manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are the most commonly searched types of Computer System Validation jobs in Pennsylvania? The most popular types of Computer System Validation jobs in Pennsylvania are:
What are popular job titles related to Computer System Validation Manager jobs in Pennsylvania? For Computer System Validation Manager jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Pennsylvania look for? The top searched job categories for Computer System Validation Manager jobs in Pennsylvania are:
What cities in Pennsylvania are hiring for Computer System Validation Manager jobs? Cities in Pennsylvania with the most Computer System Validation Manager job openings:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Pennsylvania as of July 2026, with employment types broken down into 1% As Needed, 77% Full Time, 17% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 78% Physical, 5% Hybrid, and 17% Remote job distribution, with an average salary of $105,668 per year, or $50.8 per hour.
CSV and Lab Application Support Specialist

CSV and Lab Application Support Specialist

Frontage Laboratories

Exton, PA • On-site

Full-time

Medical, Dental, Life, Retirement

Posted 25 days ago

Job description

CSV and Lab Application Support Specialist

Title: CSV and Lab Application Specialist

Location: Exton, PA

Reports to: Senior Director IT Infrastructure

Full-time (40 hrs./week) on site


Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.


Position/Job Summary:

As subject matter expert (SME), the CSV and lab application specialist define and maintain Frontage lab computer system validation program and responsible for testing, implementation, validation and date to date support of software applications.

The primary responsibilities of this position will be to perform lab software/application implementation and validation, administration, data management, user support, troubleshooting cross Frontage lab to meet GxP requirements on computer systems in lab.


Roles & Responsibilities:

  • Ensure Frontage lab global computer system validation program meets both business and regulatory requirements. Assist with client and FDA audits as necessary.
  • Provide validation support for Bioanalytical, DMPK, Biologics, Clinical and IT as needed.
  • Leverage validation efforts across sites and enterprise computer system solutions as appropriate.
  • Provide support, training and guidance for validation projects.
  • Maintain a computer inventory of computer system/software
  • Maintain validated state of software through periodic reviews, change controls and review of and implementation of upgrades as needed.
  • Provide application support for lab software systems in general. Provide focused support for key systems: i.e., Watson LIMS/Sciex Analyst/QuickBase/IDBS E-WorkBook, eBinder etc.
  • Resolve user problems and provide training as necessary.
  • Evaluate and implement new software-based technologies as needed.
  • Support user account and application access control
  • Manage and interact with system vendor to escalate and resolve issues
  • Provide support, instrument qualification and software validation, enhancement, and administration of laboratory instruments and related software.
  • Support lab software application configurations related to lab instrumentations.
  • Complete documentation for the support of software changes and upgrades.
  • Drive technology improvements and efficiency opportunities to improve business and compliance.
  • Contribute to change controls and procedures specific to laboratory software.
  • Coordinate/interface/host vendors on site, when applicable.
  • Provide training in software access and functionality.
  • Ensure the software applications are validated to 21 CFR Part 1 compliance and always maintained in validated state.
  • Other duties as assigned.


Education, Experience & Skills Required:

  • Bachelor's degree in relevant scientific, engineering, or computer-based area with 5 years' experience in the pharmaceutical industry or equivalent combination of education and IT and/or lab experience.
  • Knowledge of GxP regulatory requirements, computerized analytical systems (i.e., 21 CFR part 11) and data integrity.
  • Expert in lab systems such as Watson LIMS, IDBS eNotebook,, NUGENUSIS, Waters’ Empower Administration and other software programs, including Microsoft Office Applications.
  • Must have GxP experience.
  • Excellent organization, planning, and communication skills.


Salary and Benefits:

Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.