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Computer Information Systems Jobs in Missouri (NOW HIRING)

Weissman

Systems Administrator

Saint Louis, MO · On-site

Support a 24x7 production environment, including participation in off-hours maintenance and on-call support as needed QUALIFICATIONS Education Bachelor's degree in Computer Information Systems or a ...

Control Devices LLC

IT Systems Administrator

Fenton, MO · On-site

Bachelor's degree in information technology, Computer Science, Information Systems, or a related field required. Experience * 5+ years of hands-on systems administration in a Windows Server / Active ...

Walmart

Principal, Software Engineer

Anderson, MO · On-site

$110K - $220K/yr

Option 1: Bachelor's degree in computer science, computer engineering, computer information systems, software engineering, or related area and 5 years' experience in software engineering or related ...

Walmart

Principal, Software Engineer

Noel, MO · On-site

$110K - $220K/yr

Option 1: Bachelor's degree in computer science, computer engineering, computer information systems, software engineering, or related area and 5 years' experience in software engineering or related ...

Walmart

(USA) Software Engineer III

Noel, MO · On-site

$90K - $180K/yr

Option 1: Bachelor's degree in computer science, Computer Engineering, Computer Information Systems, Software Engineering, or a related field, with 7 years of professional experience in SAP Security ...

Walmart

Principal, Software Engineer

Cassville, MO · On-site

$110K - $220K/yr

Option 1: Bachelor's degree in computer science, computer engineering, computer information systems, software engineering, or related area and 5 years' experience in software engineering or related ...

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How much do computer information systems jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for computer information systems in Missouri is $23.53, according to ZipRecruiter salary data. Most workers in this role earn between $18.03 and $27.74 per hour, depending on experience, location, and employer.

What is computer information systems?

Computer Information Systems (CIS) is a field that focuses on the use of computer technology to solve business problems and manage information. It combines elements of computer science, business, and information technology to design, implement, and manage systems for organizations. Professionals in CIS analyze business needs, develop software and databases, and ensure the security and efficiency of IT infrastructure. The field offers diverse career opportunities, including systems analysis, network administration, and IT project management.

What are the key skills and qualifications needed to thrive in computer information systems, and why are they important?

The qualifications to get a job in CIS include a bachelor’s degree in computer science, information technology, or a related field and relevant experience. Several universities and colleges in the United States have begun to offer degrees in computer information systems, but the specialized subject is still not commonly available. A CIS job requires strong technical, problem-solving, and organizational skills, as well as programming knowledge in languages like Python, C, and Java. If you work on the database or administrative side, knowledge of SQL is also helpful.

What types of projects do computer information systems professionals typically work on within an organization?

Computer Information Systems professionals are often involved in projects that bridge the gap between business needs and technology solutions. This includes developing and maintaining databases, implementing enterprise software, optimizing IT processes, and supporting data analytics efforts. They frequently collaborate with departments like finance, marketing, and operations to ensure that technology supports organizational goals and improves efficiency. Their work may also involve troubleshooting system issues and training end-users on new technologies.

What is the difference between Computer Information Systems vs Computer Science?

AspectComputer Information SystemsComputer Science
CredentialsBachelor's in CIS, certifications like CompTIA, CiscoBachelor's in CS, certifications like Cisco, Microsoft
Work EnvironmentBusiness settings, IT support, systems managementResearch, software development, algorithms
Industry UsageCorporate, healthcare, financeTech companies, academia, research labs

Computer Information Systems focuses on applying technology solutions within organizations, emphasizing systems management and support. In contrast, Computer Science centers on developing new algorithms and software. Both fields share certifications and work environments but serve different career paths.

What can you do with a computer information systems degree?

A computer information systems degree prepares individuals for roles such as systems analyst, network administrator, database manager, or IT support specialist. Graduates can work in various industries, managing information technology systems, implementing software solutions, and ensuring cybersecurity. The degree often involves learning programming, networking, and database management, with certifications like CompTIA or Cisco enhancing job prospects.
More about Computer Information Systems jobs

What are the most commonly searched types of Computer Information Systems jobs in Missouri?

The most popular types of Computer Information Systems jobs in Missouri are:

What are popular job titles related to Computer Information Systems jobs in Missouri?

For Computer Information Systems jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Computer Information Systems jobs in Missouri look for?

The top searched job categories for Computer Information Systems jobs in Missouri are:

What cities in Missouri are hiring for Computer Information Systems jobs?

Cities in Missouri with the most Computer Information Systems job openings:

Computer Information Systems jobs near you
Infographic showing various Computer Information Systems job openings in Missouri as of August 2026, with employment types broken down into 1% As Needed, 73% Full Time, 24% Part Time, and 2% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $48,949 per year, or $23.5 per hour.

IT Systems Analyst - Epic Hospital Billing

CoxHealth

Springfield, MO

Full-time

Medical, Dental, Vision, Retirement

Posted 15 days ago

CoxHealth rating

6.7

Company rating: 6.7 out of 10

Based on 237 frontline employees who took The Breakroom Quiz

534th of 898 rated healthcare providers

Job description

Facility:

West Campus (Chase): 303 E Republic Rd, Springfield, Missouri, United States of America, 65807

Department:

1703 IT Epic Implementation

Scheduled Weekly Hours:

40

Hours:

8:00 AM – 5:00 PM

Work Shift:

Day Shift (United States of America)

CoxHealth is a leading healthcare system serving 25 counties across southwest Missouri and northern Arkansas. The organization includes six hospitals, 5 ERs, and over 80 clinics. CoxHealth has earned the following honors for workplace excellence:

  • Named one of Modern Healthcare’s Best Places to work five times.

  • Named one of America’s Greatest Workplaces, Greatest Workplaces in Healthcare (2025, 2026), Greatest Workplaces for Women (2023, 2024), and Greatest Workplaces for Diversity (2024) by Newsweek and Plant-A Insights Group. 

  • Acknowledged by Forbes as one of the Best Employers for New Grads.

  • Healthcare Innovation's Top Companies to Work for in Healthcare (2025).

Benefits

  • Medical, Vision, Dental, Retirement with Employer Match and more (20+ hrs/week)  

  • For a comprehensive list of benefits, please click here: Benefits | CoxHealth

Job Description:

The IT Systems Analyst is responsible for designing, testing, implementing, and troubleshooting IT applications and for ensuring the availability, stability, and reliability of those applications. They monitor system performance, identify, and resolve technical issues, and ensure efficient operation of all clinical systems. The analyst also provides technical support to end-users and collaborates with other IT teams to resolve complex technical problems related to clinical systems.Education: ▪ Preferred:  Associate degree in Computer Science, Information Systems, Healthcare Administration, a related field, or equivalent experience. Experience: ▪ Required: 2 years of experience in healthcare clinical workflows and/or IT support, including experience with nursing, provider, or ancillary department technologies OR Associate degree in Computer Science, Information Systems, Healthcare Administration, a related field.Skills: • Basic understanding of healthcare operations and clinical workflows • Basic knowledge of inter-related solutions and IT systems knowledge with the aligned application domain.  Develops and maintains knowledge of related IT systems as well as supporting business and IT domains. • Basic analytical and problem-solving skills; attention to detail. • Good communication and interpersonal skills. • Ability to work as part of a team. • Willingness to learn and adapt to the healthcare environment.Licensure/Certification/Registration: ▪ N/A

What CoxHealth employees say

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