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Comparative Effectiveness Jobs (NOW HIRING)

Servier

Associate Director, HEOR & RWE

Boston, KY · On-site

Lead the development of comprehensive evidence strategy (e.g., economic, comparative effectiveness) and operational plans for pipeline assets, with a focus on establishing early value propositions ...

Servier

Associate Director, HEOR & RWE

Boston, KY · On-site

Lead the development of comprehensive evidence strategy (e.g., economic, comparative effectiveness) and operational plans for pipeline assets, with a focus on establishing early value propositions ...

UCB

RWE Strategy Lead, Developed Brands

Boston, MA · On-site

Provide strategic guidance on topics including disease burden, natural history, comparative effectiveness, long-term outcomes, drug utilization, safety commitments, and health technology assessment ...

New

The Harris Center

Outcome Analyst

Houston, TX

Stays abreast of changes in database methods, processes of behavioral health care delivery, and current analytic methodologies, including cost effectiveness and comparative effectiveness study ...

UCB

RWE Strategy Lead, Developed Brands

Boston, MA · On-site

Provide strategic guidance on topics including disease burden, natural history, comparative effectiveness, long-term outcomes, drug utilization, safety commitments, and health technology assessment ...

Slipstream IT

Statistical Analytical Programmer

PA · On-site +1

Experience supporting retrospective cohort, natural history, burden of illness, comparative effectiveness, and other epidemiologic study designs. Strong programming skills in SAS , with R experience ...

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Comparative Effectiveness information

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$63

$81

How much do comparative effectiveness jobs pay per hour?

As of Aug 6, 2026, the average hourly pay for comparative effectiveness in the United States is $63.51, according to ZipRecruiter salary data. Most workers in this role earn between $50.48 and $77.88 per hour, depending on experience, location, and employer.

What is the difference between Comparative Effectiveness vs Clinical Research Coordinator?

AspectComparative EffectivenessClinical Research Coordinator
Primary FocusEvaluating the effectiveness of healthcare interventionsManaging clinical trials and research studies
Required CredentialsMaster's degree or higher in health sciences or related fieldsBachelor's degree; often certification in clinical research
Work EnvironmentHealthcare settings, research institutions, policy analysisHospitals, research centers, clinical trial sites
Industry UsageHealthcare policy, evidence-based medicine, health services researchClinical trial management, research compliance

Comparative Effectiveness professionals analyze and compare healthcare interventions to determine the best options for patient care, often working in policy or research settings. Clinical Research Coordinators manage the day-to-day operations of clinical trials. While both roles are involved in healthcare research, Comparative Effectiveness focuses on evaluating interventions' outcomes, whereas Clinical Research Coordinators handle trial logistics and compliance.

What are the key skills and qualifications needed to thrive as a comparative effectiveness researcher, and why are they important?

To thrive as a Comparative Effectiveness Researcher, you need a strong background in epidemiology, biostatistics, and health outcomes research, typically supported by an advanced degree in public health, pharmacy, or a related field. Proficiency with statistical software (such as SAS, R, or STATA) and knowledge of evidence synthesis methods are essential. Analytical thinking, attention to detail, and effective communication skills help translate complex findings for diverse stakeholders. These skills ensure rigorous, actionable research that informs healthcare decision-making and improves patient outcomes.

What is comparative effectiveness research?

Comparative effectiveness research (CER) is a field of study that compares different healthcare interventions and strategies to determine which work best for specific populations or conditions. The goal is to provide evidence on the effectiveness, benefits, and harms of various treatment options so patients and healthcare providers can make informed decisions. CER often uses real-world data and clinical trials to evaluate how treatments perform in routine practice, not just controlled settings. This research helps improve healthcare outcomes and ensures resources are used efficiently.

How does a comparative effectiveness professional typically collaborate with clinicians and data scientists to inform healthcare decision-making?

Comparative Effectiveness professionals frequently work in interdisciplinary teams, partnering with clinicians to understand real-world patient outcomes and with data scientists to analyze large healthcare datasets. Their role often involves translating complex statistical findings into actionable insights for healthcare providers and policymakers. Regular meetings, joint research projects, and cross-functional workshops are common, ensuring that research findings are both methodologically sound and practically relevant. This collaborative approach helps bridge the gap between analytical research and clinical practice, making it essential for professionals in this field to have strong communication and teamwork skills.
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Comparative Effectiveness jobs near you
Infographic showing various Comparative Effectiveness job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, and 2% Contract. Highlights an 90% Physical, 4% Hybrid, and 6% Remote job distribution, with an average salary of $132,108 per year, or $63.5 per hour.

Associate Director, Health Economics & Outcomes Research/Real-World Evidence (HEOR/RWE)

Mineralys Therapeutics

Remote

$175K - $200K/yr

Full-time

Posted 8 days ago

Job description

"Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky"
Mineralys is a fully remote company.
Position Summary:
The Associate Director, HEOR / Real-World Evidence (RWE) plays a strategic and scientific leadership role in developing and executing evidence strategies that support the clinical and economic value of our innovative therapy. This position is responsible for designing and delivering real-world and outcomes research evidence to support medical affairs, market access, and regulatory objectives. The role focuses on generating high-quality, decision-relevant evidence, including observational studies, external control arms, and economic models, and indirect treatment comparisons, to contextualize clinical outcomes, demonstrate value, and support stakeholder decision- making.
The Associate Director collaborates cross-functionally with Medical Affairs, biostatistics, and commercial teams, while also engaging external partners such as academic researchers, key opinion leaders, and data vendors. This role contributes to strategic evidence planning, scientific communication, and advancing real-world data capabilities within a matrixed organization.
Key Responsibilities:
  • Lead the design, execution, and oversight of HEOR and RWE studies, including observational studies (retrospective/prospective cohorts), economic models, external control arms and indirect treatment comparisons.
  • Oversee data analysis ensuring methodological rigor and contribute to research reports for internal and external consumption.
  • Develop and execute integrated HEOR strategies aligned with product development and market access needs.
  • Identify evidence gaps and define research strategies to address unmet needs, burden of disease, and treatment pathways.
  • Support development of value messaging tools (e.g., cost-effectiveness models, budget impact models).

Cross-functional Collaboration & Stakeholder Engagement
  • Partner cross-functionally with Medical Affairs, Clinical Development, Market Value & Access and Commercial teams to align with data needs.
  • Build and manage relationships with external experts, academic collaborators, and vendors.
  • Provide HEOR/RWE expertise to support interactions with HTA agencies.
  • Lead publication planning and development of HEOR/RWE abstracts, manuscripts, and presentations for scientific congresses and peer-reviewed journals.

Operational Leadership & Governance
  • Oversee vendor selection and management, ensuring timely, high-quality study execution.
  • Manage timelines, budgets, and deliverables across multiple projects
  • Ensure all HEOR activities adhere to compliance guidelines, internal SOPs, regulatory standards, and ethical guidelines for RWD and economic modeling.

Qualifications:
  • Advanced degree required (PhD, PharmD, MD, MPH, or similar) in health economics, outcomes research, biostatistics, epidemiology or related field.
  • Minimum of 5 years of relevant experience in HEOR, RWE, or outcomes research in pharmaceutical, biotech, consulting, or academic settings.
  • Strong analytical skills and strong understanding of observational study design, real-world data sources (claims, EMR, registries), and health economic modeling.
  • Experience with burden of illness studies, and comparative effectiveness research.
  • Familiarity HTA requirements and RWE regulatory landscape.
  • Demonstrated ability to successfully lead complex research projects independently and collaboratively.
  • Strong communication, and scientific writing skills, including publication track record.
  • Proven cross-functional collaboration and stakeholder engagement capabilities.

Travel:
  • This position requires up to 20% travel. Frequently travel is outside the local area and overnight.

US Salary Range: $175,000 - $200,000
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