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Clinical Research Manager Jobs (NOW HIRING)

Tufts University

Clinical Research Manager

Boston, MA · On-site

$74K - $111K/yr

What You'll Do The Clinical Research Program Manager is the operational lead of the Coordinating Center for a multi-site Lyme disease research program spanning three regional hubs and more than 20 ...

Envista

Clinical Research Manager

Brea, CA · On-site

$125K - $153K/yr

The Clinical Research Manager is responsible for managing all US clinical usability studies for Restorative, Endodontics and Preventive, making sure that all studies follow regulatory standards for ...

Horizon Clinical Research

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Clinical Research Assistant

Cypress, TX · On-site

$37K - $47K/yr

The CRA will work under the supervision of the Principal Investigator(s) and Site research manager and will include all study related activities during the clinical research timeline from pre-site ...

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$49K

$107.3K

$189K

How much do clinical research manager jobs pay per year?

As of Aug 18, 2026, the average yearly pay for clinical research manager in the United States is $107,336.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,000.00 and $122,500.00 per year, depending on experience, location, and employer.

What does a clinical research manager do?

A clinical research manager oversees clinical trials, which involve testing new medications or medical devices. Their responsibilities include ensuring all ethical practices and legal protocols are followed and that all paperwork is filled out completely and accurately. They also maintain standards for the data collection and procedures during the clinical trial and make sure all team members, including the doctors and nurses on the trial, are kept informed.

What are the key skills and qualifications needed to thrive as a clinical research manager?

To thrive as a Clinical Research Manager, you need a solid understanding of clinical trial protocols, regulatory requirements (such as GCP), and a background in life sciences or healthcare, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), EDC software, and certifications like ACRP or SOCRA are typically expected. Strong leadership, excellent organizational skills, and effective communication abilities set outstanding managers apart. These competencies are critical for ensuring compliance, data integrity, and the successful coordination of multidisciplinary research teams.

What are some common challenges clinical research managers face when overseeing multiple clinical trials simultaneously?

Clinical Research Managers often encounter challenges such as balancing competing timelines, ensuring regulatory compliance across different studies, and effectively allocating resources among projects. Managing communication between diverse teams—such as investigators, sponsors, and regulatory bodies—can also be demanding, especially when trials are at different stages. Developing strong organizational skills and leveraging project management tools are key to successfully navigating these complexities and maintaining high standards for data quality and participant safety.

What is the difference between Clinical Research Manager vs Clinical Research Coordinator?

AspectClinical Research ManagerClinical Research Coordinator
CredentialsBachelor's or higher in life sciences, often with experience in project managementBachelor's in health sciences or related field, often with certification like CCRP
Work EnvironmentOversees multiple studies, manages teams, and ensures compliance at a higher levelAssists with daily study activities, patient interactions, and data collection
Employer & Industry UsagePharmaceutical companies, CROs, academic institutionsHospitals, clinics, research sites

The Clinical Research Manager focuses on overseeing entire studies and managing teams, while the Clinical Research Coordinator handles daily study tasks and participant interactions. Both roles require relevant certifications and are essential in clinical research settings, but they differ in scope and responsibilities.

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Clinical Research Manager jobs near you
Infographic showing various Clinical Research Manager job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $107,336 per year, or $51.6 per hour.

Clinical Research Manager

Tufts University

Boston, MA • On-site

$74K - $111K/yr

Full-time

Posted 19 days ago

Tufts University rating

8.4

Company rating: 8.4 out of 10

Based on 25 frontline employees who took The Breakroom Quiz

99th of 618 rated colleges and universities

Job description

Overview
The Department of Molecular Biology and Microbiology at Tufts University School of Medicine works to improve global health by using molecular genetics and innovation to address fundamental and medically related problems in microbiology. Training is a core tenet of the department's approach, with students, postdocs, and staff serving as key drivers of its scientific impact. Founded on community building, mentorship, and collaboration, the department is committed to fostering a diverse, inclusive scientific community that welcomes a range of perspectives to produce more innovative and impactful science.
What You'll Do
The Clinical Research Program Manager is the operational lead of the Coordinating Center for a multi-site Lyme disease research program spanning three regional hubs and more than 20 clinical and data-collection sites across New England. Reporting to study leadership, this role provides study-wide project management and serves as the primary regulatory lead for the Tufts single IRB, coordinating across clinical operations, data management, laboratory operations, investigative project teams, documentation, training, and stakeholder communications. The ideal candidate brings strong clinical research operations experience, excellent organizational and communication skills, and the ability to manage complex timelines, cross-functional workflows, and competing priorities across multiple institutions.
  • Serve as the operational center of the study through the Coordinating Center, which owns and drives study-wide infrastructure and execution, including procedures, training, participant materials, progress tracking, and cross-group coordination.
  • Serve as primary regulatory lead for the Tufts single IRB of record: prepare and maintain submissions, modifications, continuing reviews, reportable new information, consent revisions, reliance agreements, and the study regulatory binder; advise investigators and site staff on compliance strategy across sites.
  • Maintain study-wide timelines, milestones, and dependencies; manage risks, decisions, and action items using appropriate project-management tools; and oversee implementation of protocol amendments and operational changes across all hubs and sites.
  • Create, maintain, and update study Manuals of Procedures, SOPs, workflows, and controlled documentation.
  • Develop and deliver onboarding, refresher, and ongoing training and guidance for study coordinators and site staff across hubs.
  • Track enrollment and retention across hubs and sites, identify barriers, develop participant-facing retention materials, and work with hub teams on solutions.
  • Serve as operational liaison to the Diagnostic Core (sample-kit logistics, specimen workflows, enrollment-season readiness, consent preferences) and the Data Center (REDCap updates, data requests, reports, data-quality activities), keeping deliverables on schedule and resolving bottlenecks.
  • Oversee Tufts hub operations and Tufts-affiliated sites, including site activation, enrollment preparation, and ongoing support; train, onboard, supervise, and support Tufts study coordinators and delegated staff.
    Serve as the operational link among the investigative project teams, Data Center, and Diagnostic Core to support sample requests, clinical and diagnostic data needs, analysis support, and selection criteria; prepare enrollment and retention metrics and progress reports for leadership and external stakeholders.

What We're Looking For
Basic Requirements:
Knowledge and experience typically acquired by:
  • Advanced degree in clinical research, public health, project management, health administration, life sciences, nursing, or a related field, or equivalent experience.
  • At least 5 years of progressively responsible clinical research experience, including managing complex, multi-site or multi-institutional studies.
  • Strong IRB experience, including single-IRB oversight and negotiating or managing reliance agreements.
  • Demonstrated project-management experience: timeline development, milestone tracking, risk management, dependency tracking, and stakeholder communication.
  • Experience supervising, training, or leading clinical research staff.
  • Experience developing and maintaining MOPs, SOPs, training materials, study workflows, onboarding tools, or controlled documentation.
  • Experience supporting study recruitment, enrollment tracking, participant retention, and follow-up workflows, including developing participant-facing retention materials.
  • Ability to coordinate work across clinical operations, regulatory, data-management, laboratory, and investigator teams.
  • Excellent written and verbal communication skills; strong organizational skills and ability to manage multiple priorities in a fast-paced, highly collaborative environment.
  • Knowledge of Good Clinical Practice, human-subjects protections, HIPAA, and applicable clinical research regulations.
  • Ability to travel to clinical sites as needed.

Preferred Qualifications:
  • Experience managing NIH-funded clinical or translational research.
  • Familiarity with REDCap sufficient to understand data-team workflows and communicate effectively about data collection, reports, and database changes.
  • Ability to independently access and analyze study data using R, SAS, Python, or similar tools to build enrollment, retention, and operational reports that inform decisions.
  • Experience coordinating biospecimen collection, laboratory workflows, or biorepository procedures.
  • Formal project-management training or certification.
  • Familiarity with infectious-disease, longitudinal studies, or biorepository research

Pay Range
Minimum $74,000.00, Midpoint $92,500.00, Maximum $111,000.00
Salary is based on related experience, expertise, and internal equity; generally, new hires can expect pay between the minimum and midpoint of the range.

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