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Clinical Research Associate 1099 Jobs in Springfield, IL

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Clinical Research Associate 1099 information

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$35.7K

$93.5K

$142.2K

How much do clinical research associate 1099 jobs pay per year?

As of Sep 4, 2026, the average yearly pay for clinical research associate 1099 in Springfield, IL is $93,476.00, according to ZipRecruiter salary data. Most workers in this role earn between $61,900.00 and $126,900.00 per year, depending on experience, location, and employer.

What is a clinical research associate 1099?

A Clinical Research Associate (CRA) 1099 is an independent contractor who oversees clinical trials for pharmaceutical, biotechnology, or medical device companies. Unlike traditional W-2 employees, CRAs working under a 1099 agreement operate as self-employed professionals, managing their own taxes and benefits. Their responsibilities include monitoring study sites, ensuring compliance with protocols, and safeguarding patient safety and data integrity. This role offers more flexibility but also requires handling administrative tasks that would typically be managed by an employer.

What are the key skills and qualifications needed to thrive as a clinical research associate 1099?

To thrive as a Clinical Research Associate 1099, you need a solid understanding of clinical trial protocols, GCP (Good Clinical Practice) guidelines, and typically a bachelor’s degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and often certifications like ACRP or SOCRA are important. Strong organizational skills, attention to detail, and effective communication enable you to manage multiple studies and collaborate with diverse teams. These skills ensure compliance, data integrity, and the successful execution of clinical research projects.

What are some common challenges independent (1099) clinical research associates face, and how can they be managed?

Independent Clinical Research Associates (CRAs) often face challenges such as managing multiple sponsor expectations, maintaining consistent study documentation, and navigating variable workloads. As a 1099 contractor, you are responsible for your own scheduling, invoicing, and tax obligations, which requires strong organizational skills. Building clear communication channels with sponsor teams and staying updated on regulatory requirements can help ensure study quality and compliance. Networking with other independent CRAs and utilizing professional resources can also provide support and guidance.

What is the difference between Clinical Research Associate 1099 vs Clinical Research Associate W-2?

AspectClinical Research Associate 1099Clinical Research Associate W-2
Employment StatusIndependent contractorEmployee
TaxationResponsible for own taxes, self-employedTaxes withheld by employer
Work EnvironmentTypically contract-based, flexible locationsUsually full-time, in-house or site-based
CredentialsOften similar certifications, e.g., CCR, but no employer-mandated benefitsSame certifications, with benefits provided by employer

The main difference between a Clinical Research Associate 1099 and a W-2 is employment status. The 1099 role is an independent contractor, offering flexibility but requiring self-management of taxes and benefits. The W-2 role is a traditional employee position with taxes and benefits handled by the employer. Both roles often require similar credentials and work in comparable environments, but their employment structure impacts taxes, benefits, and work arrangements.

What job categories do people searching Clinical Research Associate 1099 jobs in Springfield, IL look for?

The top searched job categories for Clinical Research Associate 1099 jobs in Springfield, IL are:

What cities near Springfield, IL are hiring for Clinical Research Associate 1099 jobs?

Cities near Springfield, IL with the most Clinical Research Associate 1099 job openings:

Orthopaedic Trauma Surgeon (Assistant or Associate Professor) - SMS-3341

Southern Illinois University School of Medicine

Springfield, IL • On-site

Other

Medical, Dental, Life, Retirement, PTO

Re-posted 11 days ago


Job description

Location : Springfield, IL
Job Type: Faculty
Job Number: N2301792
Department: Surgery-SMS
Division: Orthopaedic Surgery
Opening Date: 12/08/2023
Closing Date: Continuous
FLSA: Exempt
Bargaining Unit: N/A
Shift: Days
ExemptorNon_Exempt: Exempt
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Description
The incumbent will function as a faculty member in the Department of Surgery, in the Division of Orthopaedics and Rehabilitation. The incumbent will be responsible for active participation in the development and delivery of instructional activities to students, residents, and allied health professionals and for service and research functions related to specialty interest and expertise.
Examples of Duties
I. Administration 5%
This individual will perform administrative duties as requested by the Chairman of the Division of Orthopaedics and Rehabilitation
II. Teaching 15%A. Participate in the development and implementation of specific undergraduate curricula in orthopaedic trauma.
B. Participate directly in orthopaedics and rehabilitation residency training.
C. Act as a mentor on the Basic Surgical Clerkship.
D. Provide a role model as a practitioner/teacher for faculty, house staff, and students.
E. Serve as resource to hospital staff concerning the clinical management of orthopaedic trauma patients.
F. Participate in continuing education programs in orthopaedics within the clinical faculty and for practicing physicians in the area
III. Research 15%
A. Stimulate and initiate clinical research efforts in the areas of trauma and orthopaedics.
B. Seek extra and intramural grant support.
C. Provide a role model as an investigator and medical writer to residents/medical students
IV. Service 50%
A. Demonstrates, by actions, commitment to the mission and the behavioral standards of SIU School of Medicine. Provides excellent service to both internal and external customers through collaboration and partnership; compassion and respect; integrity and accountability, diversity and inclusion; as well as continuous learning and improvement
B Work on programmatic issues relating to the development, implementation, and coordination of the community-wide trauma program.
D. Set an example of highly skilled and conscientious practice of surgery that is balanced with self-education and other academic activities as an example to future practitioners of surgery in the area.
E. Maintain a surgical practice in order to maintain clinical proficiency.
F. Share in Orthopaedic call schedule.
F. Participate in departmental, University and hospital committees.
H. Represent the Division in departmental, School, University, hospital and community matters as requested.
I. Assist in the development of programs for the care of the hospitalized patient.
Qualifications
  1. Sensitive to the needs of underrepresented minority populations
  2. Graduate of accredited medical school program
  3. Licensed to practice medicine in the State of Illinois or eligible for such licensure
  4. Successful completion of an Orthopaedic residency program
  5. Board Eligible or Board Certified in Orthopaedic Surgery
  6. Graduate of formal specialty training program in Trauma

Supplemental Information
If you require assistance, please contact the Office of Human Resources at or call 217-545-0223 Monday through Friday, 8:00am-4:30pm.
The mission of Southern Illinois University School of Medicine is to optimize the health of the people of central and southern Illinois through education, patient care, research and service to the community.
The SIU School of Medicine Annual Security Report is available online at This report contains policy statements and crime statistics for Southern Illinois University School of Medicine in Springfield, IL. This report is published in compliance with Federal Law titled the
"Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act."
Southern Illinois University School of Medicine is an Affirmative Action/Equal Opportunity employer who provides equal employment and educational opportunities for all qualified persons without regard to race, color, religion, sex, national origin, age, disability, sexual orientation, protected veteran status or marital status in accordance with local, state and federal law.
Pre-employment background screenings required.
Paid time off: Includes 12 paid holidays per year. Accrual rates vary based on employment type and years of service
Paid sick time: Use for personal illness, doctor visits, or if your immediate family members fall ill
Health, Dental, and Life insurance
Optional life insurance: Your spouse and dependents can enroll in State term life and university-sponsored term life insurance.
Prescription: Plan participants enrolled in any state health plan have prescription drug benefits included in the coverage.
Long-term Disability Insurance
Flexible spending accounts: Optional, IRS tax-favored program that enables you to stretch medical expenses and dependent care dollars
Voluntary retirement accounts: Optional plans include the State of Illinois Deferred Compensation Plan (457) and Tax Deferred Annuity (403b).
Tuition Waiver/Tuition Reimbursement: Continue your graduate or undergraduate education with the help of tuition waivers or tuition reimbursement
Leaves of absence: Includes FMLA and Extended Sick Leave Benefits for qualified employees
Employee Assistance Program: Access free and confidential support, including counseling services, and information during difficult times
For more information please visit