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Clinical Research Associate 1099 Jobs in Springfield, IL

Oncology Research Liaison

Springfield, IL · On-site

$24 - $32/hr

Collaborate with Clinical Research Associates (CRAs) and study monitors to ensure data accuracy, resolve discrepancies, and maintain audit readiness. This coordination and collaboration could include:

Clinical Research Specialist

Springfield, IL · On-site

$22.05 - $33.08/hr

Associate degree in a science or healthcare related field or a degree in nursing required; high ... Research certification preferred. * Human Subject Protection and Good Clinical Practices Training ...

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Clinical Research Associate 1099 information

See Springfield, IL salary details

$35.7K

$93.5K

$142.2K

How much do clinical research associate 1099 jobs pay per year?

As of Aug 10, 2026, the average yearly pay for clinical research associate 1099 in Springfield, IL is $93,476.00, according to ZipRecruiter salary data. Most workers in this role earn between $61,900.00 and $126,900.00 per year, depending on experience, location, and employer.

What is a clinical research associate 1099?

A Clinical Research Associate (CRA) 1099 is an independent contractor who oversees clinical trials for pharmaceutical, biotechnology, or medical device companies. Unlike traditional W-2 employees, CRAs working under a 1099 agreement operate as self-employed professionals, managing their own taxes and benefits. Their responsibilities include monitoring study sites, ensuring compliance with protocols, and safeguarding patient safety and data integrity. This role offers more flexibility but also requires handling administrative tasks that would typically be managed by an employer.

What are some common challenges independent (1099) clinical research associates face, and how can they be managed?

Independent Clinical Research Associates (CRAs) often face challenges such as managing multiple sponsor expectations, maintaining consistent study documentation, and navigating variable workloads. As a 1099 contractor, you are responsible for your own scheduling, invoicing, and tax obligations, which requires strong organizational skills. Building clear communication channels with sponsor teams and staying updated on regulatory requirements can help ensure study quality and compliance. Networking with other independent CRAs and utilizing professional resources can also provide support and guidance.

What are the key skills and qualifications needed to thrive as a clinical research associate 1099?

To thrive as a Clinical Research Associate 1099, you need a solid understanding of clinical trial protocols, GCP (Good Clinical Practice) guidelines, and typically a bachelor’s degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, regulatory documentation, and often certifications like ACRP or SOCRA are important. Strong organizational skills, attention to detail, and effective communication enable you to manage multiple studies and collaborate with diverse teams. These skills ensure compliance, data integrity, and the successful execution of clinical research projects.

What is the difference between Clinical Research Associate 1099 vs Clinical Research Associate W-2?

AspectClinical Research Associate 1099Clinical Research Associate W-2
Employment StatusIndependent contractorEmployee
TaxationResponsible for own taxes, self-employedTaxes withheld by employer
Work EnvironmentTypically contract-based, flexible locationsUsually full-time, in-house or site-based
CredentialsOften similar certifications, e.g., CCR, but no employer-mandated benefitsSame certifications, with benefits provided by employer

The main difference between a Clinical Research Associate 1099 and a W-2 is employment status. The 1099 role is an independent contractor, offering flexibility but requiring self-management of taxes and benefits. The W-2 role is a traditional employee position with taxes and benefits handled by the employer. Both roles often require similar credentials and work in comparable environments, but their employment structure impacts taxes, benefits, and work arrangements.

What job categories do people searching Clinical Research Associate 1099 jobs in Springfield, IL look for? The top searched job categories for Clinical Research Associate 1099 jobs in Springfield, IL are:
What cities near Springfield, IL are hiring for Clinical Research Associate 1099 jobs? Cities near Springfield, IL with the most Clinical Research Associate 1099 job openings:

Clinical Research Coordinator

Springfield Clinic

Springfield, IL • On-site

$24 - $32/hr

Other

Re-posted 8 days ago


Springfield Clinic rating

6.7

Company rating: 6.7 out of 10

Based on 59 frontline employees who took The Breakroom Quiz

531st of 887 rated healthcare providers


Job description

The Clinical Research Coordinator serves as the principal study contact and implements clinical research study activities between the Clinical Research Department, SC Investigators, SC staff, and the pharmaceutical and medical device study sponsors.

Job Relationships

  • Reports to the Clinical Research Manager

Principal Responsibilities

  • Plan and coordinate the initiation of assigned IRB approved clinical trial protocols; following all federal/local requirements, ICH/GCP, OSHA, IATA requirements.
  • Responsible for screening, consenting, and enrolling eligible patients, as well as following all enrolled study patients to study completion; conduct study visits per protocol, and collect, process, and ship all lab specimens as required and as per IATA training and certification.
  • Responsible for providing SC Investigators with information about the protocol, protocol amendments, Investigator's Brochure, ICH/GCP guidelines, and other study-required training to ensure compliance with all applicable regulations and study-specific guidelines.
  • Maintain adequate and accurate source documentation in each of the study patient's medical records regarding their participation in the clinical study; accurately enter data into the sponsor's case report forms per the sponsor's guidelines; maintain accurate investigational product accountability documentation regarding the receipt, disposition, dispensation, return and destruction.
  • Monitor research patients for suspected adverse events and report serious adverse events (SAEs) and any protocol deviations to the study sponsor within the appropriate time frame; provide pertinent information for submission to the proper authorities.
  • Schedule and meet with the study monitors/Clinical Research Associates (CRAs) to:
  • Review data entry against source documentation and assist in resolving all discrepancies, including resolving data queries.
  • Liaise between the study monitor, clinic staff, and the SC Investigators to ensure that quality research is being conducted according to the IRB approved protocol, amendments, procedures, laws, and regulations.
  • Assist management team in the training and mentoring of new/ lesser experienced staff.
  • As needed, obtain and maintain Allied Health Professional appointments at the local hospitals.
  • Responsible for handling and administration of investigational product as appropriately delegated and trained per protocol-specific guidelines. As delegated, licensed RN's are responsible for the administration and oversight of investigational product via the following routes: intravenous, injectable, and/or oral.
  • Comply with the Springfield Clinic incident reporting policy and procedures.
  • Provide excellent customer service and adhere to SC Code of Conduct and Ethics Standards.
  • Perform other job duties as assigned.

Education/Experience

  • Minimum of a Bachelor's degree in a related field.
  • Licensed by the State of Illinois as an RN with three-five+ (3-5+) years of medical experience preferred.
  • Clinical Research experience strongly preferred.

Licenses/Certificates

  • CPR certification per American Heart Association guidelines required within 30 days of hire.
  • RN License in the State of IL preferred.
  • It is strongly recommended that research certification (CCRP or CCRC) is obtained after two (2) years of employment and then subsequently maintained in good standing.

Knowledge, Skills and Abilities

  • A strong working knowledge of computer software including Microsoft Office, Electronic Medical Record(s), other SC platforms, and Sponsor required systems.
  • Attention to detail and ability to follow and interpret approved clinical protocols is required.
  • A strong working knowledge of GCP, ICH, CFR, and HIPAA laws and regulations will be required.
  • Knowledge of Springfield Clinic policies and procedures.
  • Ability to demonstrate good organizational skills, excellent oral & written communication skills, and excellent interpersonal skills in working effectively with Co-workers; Managers; Directors; Administration; Providers; Staff; Sponsors and Patients.
  • Ability to recognize, evaluate and solve problems.
  • Ability to manage projects in a team environment.
  • Ability to function and perform daily work independently; perform duties and tasks assigned and follow through to completion.
  • Must have the ability to control emotions and maintain composure under stress, using tact and good judgment.
  • Must be able to stand and walk for long periods and capable of stooping, bending, and lifting.

Working Environment

  • Office based with travel to other Springfield Clinic locations (including satellite offices) and other business related travel, as required to conduct day to day business aspects of the department.

PHI/Privacy Level

  • HIPAA1

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