Clinical Informatics Manager Jobs in Pennsylvania

7,000 Diseases - 500 Treatments - 1 Rare Pharmacy

PANTHERx is the nation’s largest rare disease pharmacy, and we put the patient experience at the top of everything that we do.

If you are looking for a career in the healthcare field that embraces authentic dedication to patient care, you don’t need to look beyond PANTHERx. In every line of service, in every position and area of expertise, PANTHERx associates are driven to provide the highest quality outcomes for our patients.

We are seeking team members who:

Are inspired and compassionate problem solvers;

Produce high quality work;

Thrive in the excitement of the ever-challenging environment of modern medicine; and

Are committed to achieving superior health outcomes for people living with rare and devastating diseases.

At PANTHERx, we know our employees are the driving force in what we do. We cultivate talent and encourage growth within PANTHERx so that our associates can continue to explore their interests and expand their careers. Guided by our mission to provide uncompromising quality every day, we continue our strategic growth to further reach those affected by rare diseases.

Join the PANTHERx team, and define your own RxARE future in healthcare!

Location: Pittsburgh, PA (Hybrid)

Classification: Exempt

Status: Full-Time

Reports to: Senior Manager, Clinical Informatics

Purpose

The Senior Clinical Informatics Analyst applies clinical domain expertise to technology analysis, system design, and requirements development within the Clinical Informatics track. This role bridges clinical operations and IT delivery: translating clinical workflows and business needs into structured, testable requirements, and ensuring that system configurations, integrations, and data flows reflect the realities of clinical practice. The Senior Clinical Informatics Analyst serves as a senior practitioner and informal mentor within the track, providing clinical depth and analytical rigor that elevates the quality of requirements and system design decisions across Informatics workstreams.

Responsibilities

Clinical Analysis & Requirements

• Analyzes clinical workflows, operational processes, and business needs to develop structured technology requirements, including user stories and acceptance criteria that meet Informatics methodology standards.
• Conducts current-state and future-state workflow analysis for clinical systems, identifying gaps, risks, and design considerations before work enters delivery.
• Documents clinical requirements with sufficient precision for QA to execute acceptance criteria directly, in alignment with the Informatics-to-QA handoff standard.

System Design & Integration Support

• Provides clinical informatics input on system configuration, integration design, and data flow decisions, ensuring solutions reflect clinical workflow requirements and applicable data standards.
• Evaluates interoperability requirements for clinical systems, applying knowledge of NCPDP, HL7, and FHIR standards to ensure integration designs are clinically sound and technically executable.
• Participates in technical design reviews, contributing clinical perspective on decisions that affect pharmacy operations, patient care workflows, or clinical data integrity.

Documentation & Standards

• Produces high-quality requirements documentation, workflow diagrams, and business process models that meet the Clinical Informatics track's methodology standards.
• Maintains and updates clinical system documentation, including integration specifications, configuration guides, and workflow maps, as systems evolve.
• Contributes to the development and refinement of Clinical Informatics standards, templates, and quality benchmarks in collaboration with the Sr. Manager.

Cross-Functional Collaboration

• Partners with Business Analysts, Product Owners, and QA to ensure clinical requirements are accurate, complete, and directly usable in delivery and test execution.
• Serves as a clinical subject matter resource for Data & Analytics, IT Infrastructure, and AI teams on projects with clinical workflow or data implications.
• Mentors Clinical Informatics Analysts, providing guidance on clinical documentation standards, workflow analysis, and requirements quality.

Required Qualifications

• 5+ years of experience in clinical informatics, pharmacy informatics, clinical operations, or a closely related field.
• Demonstrated clinical domain knowledge: familiarity with pharmacy operations, clinical workflows, and the technology systems that support them.
• Proven ability to document clinical requirements with sufficient precision for technology delivery and QA test execution.
• Experience conducting workflow analysis and translating operational needs into structured technology requirements.
• Strong written communication skills: able to produce clear, precise documentation for both clinical and technical audiences.

Preferred Qualifications

• Experience in specialty pharmacy, rare disease, or high-complexity clinical environments.
• Familiarity with interoperability standards: NCPDP, HL7 FHIR, and pharmacy-specific data exchange formats.
• Exposure to clinical decision support, medication management systems, or prior authorization workflows.
• Familiarity with agile delivery practices and acceptance criteria standards sufficient to contribute directly to story-level requirements.
• Bachelor's degree in Pharmacy, Health Informatics, Nursing, Information Systems, or a related field, or equivalent experience.

Work Environment

This position works in a home office and professional office environment. When in-office this role routinely uses standard office equipment such as computers, phones, photocopiers, filing cabinets and fax machines, and communications via MS Teams.

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, see, talk or hear. The employee frequently is required to stand; walk; use hands and fingers to handle or feel; and reach with hands and arms. Visual acuity is necessary for tasks such as reading and working with various forms of data on a screen. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions of the job.

Benefits:

Hybrid, remote and flexible on-site work schedules are available, based on the position. PANTHERx Rare Pharmacy also affords an excellent benefit package, including but not limited to medical, dental, vision, health savings and flexible spending accounts, 401K with employer matching, employer-paid life insurance and short/long term disability coverage, and an Employee Assistance Program! Generous paid time off is also available to all full-time employees, as well as limited paid time off for part-time employees. Of course we offer paid holidays too!

Equal Opportunity:

PANTHERx Rare Pharmacy is an equal opportunity employer, and does not discriminate in recruiting, hiring, promotions or any term or condition of employment based on race, age, religion, gender, ethnicity, sexual orientation, gender identity, disability, protected veteran's status, or any other characteristic protected by federal, state or local laws.