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Car T Cell Therapy Jobs (NOW HIRING)

Legend Biotech US

Scientist, Solid Tumor CAR-T

Philadelphia, PA · On-site

$110K - $145K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of ...

Legend Biotech US

Scientist, Solid Tumor CAR-T

Philadelphia, PA · On-site

$110K - $145K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of ...

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How much do car t cell therapy jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for car t cell therapy in the United States is $17.41, according to ZipRecruiter salary data. Most workers in this role earn between $14.90 and $19.23 per hour, depending on experience, location, and employer.

What is a Car T Cell Therapy?

A CAR T Cell Therapy job involves researching, developing, and manufacturing personalized cancer treatments using genetically engineered T cells. Professionals in this field work in roles such as scientists, lab technicians, process engineers, and clinical specialists. Their responsibilities may include cell extraction, gene modification, quality control, and ensuring compliance with regulatory standards. These jobs are typically found in biotech companies, hospitals, and research institutions focused on advancing immunotherapy treatments.

What are the key skills and qualifications needed to thrive in Car T Cell Therapy?

To thrive in a CAR T Cell Therapy role, a strong background in cellular immunology, clinical research, and oncology is typically required, often supported by a relevant advanced degree and laboratory or clinical experience. Familiarity with cell processing technologies, GMP (Good Manufacturing Practice) compliance, and scientific data analysis tools such as flow cytometry and ELISA is essential. Strong teamwork, attention to detail, and effective communication skills help professionals collaborate across clinical, laboratory, and regulatory teams. Together, these capabilities ensure safe, high-quality development, manufacturing, and administration of CAR T cell therapies to patients.

What does a Car T Cell Therapy do?

In a CAR T Cell Therapy role, your daily tasks could include preparing and processing patient-derived cells, conducting laboratory assays to ensure product quality, and documenting results for regulatory compliance. You may also collaborate with physicians, clinical trial coordinators, and manufacturing specialists to coordinate patient treatment schedules and resolve any product-related challenges. Balancing lab work, patient-focused communication, and data management is common. The role is dynamic and collaborative, offering opportunities to contribute directly to cutting-edge cancer treatments while working as part of a multidisciplinary team.

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Car T Cell Therapy jobs near you
Infographic showing various Car T Cell Therapy job openings in the United States as of August 2026, with employment types broken down into 5% As Needed, 59% Full Time, 19% Part Time, and 17% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $36,219 per year, or $17.4 per hour.

Scientist, Solid Tumor CAR-T

Legend Biotech US

Philadelphia, PA

Full-time

Posted 22 days ago

Job description

Legend Biotech is seeking a Scientist, Solid Tumor CAR-T as part of the Research and Development team based in Philadelphia, PA. 

Role Overview

We are seeking a highly motivated Scientist to join our interdisciplinary cell therapy team at Legend Biotech, focused on advancing CAR-T cell therapies for solid tumors. This role is central to our in vivo CAR-T platform and will drive preclinical development from construct design through animal model efficacy studies.

The ideal candidate holds a PhD in Immunology, Immuno-Oncology, or a closely related discipline, with up to 3 years of postdoctoral experience. You are a rigorous scientist who thrives in a fast-paced, collaborative environment and is passionate about translating basic immunology insights into transformative oncology therapies.

Key Responsibilities

  • Design and execute in vitro CAR-T functional assays.
  • Perform comprehensive phenotypic analysis of T cell differentiation, activation, and memory subsets.
  • Evaluate CAR-T cell trafficking and tumor infiltration in vivo using flow cytometry and immunohistochemistry.
  • Handling and engineering human and murine T cells as well as various cancer cells.
  • Engineering and maintaining various cancer cell lines for model development.
  • Analyze and interpret data, troubleshooting, maintain detailed experimental records. 

Requirements

  • A scientist in Immunology, Immuno-Oncology, Tumor Immunology, Cancer Biology, or a closely related field.
  • Candidates completing ther PhD within the past 3 years are strongly encouraged to apply.
  • Primary human T cell isolation, activation, lentiviral transduction, and expansion is required.
  • Multicolor flow cytometry: panel design, data acquisition (e.g., Attune,Novocyte, Cytek Aurora), and analysis (FlowJo).
  • Standard molecular biology: PCR/qPCR, lentiviral vector packaging and titration, Western blot.
  • Experience with humanized mouse models for in vivo CAR-T evaluation.
  • Proficiency in CAR-T cell trafficking studies: IHC/IF of tumor sections, in vivo imaging.
  • Familiarity with gene editing tools (CRISPR/Cas9) for cell engineering.
  • Experience with in vitro Organoid cancer model establishment and expansion.
  • Experience in solid tumor indications (e.g., lung, gastric, or other refractory cancers).
  • Contributions to innovation in cell therapy (publications, patents, or conference presentations).

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