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Biotech Software Engineer Jobs in Boston, MA (NOW HIRING)

Prime Medicine

Informatics Engineer

Cambridge, MA · On-site

Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next ... Translate scientific requirements into reliable, maintainable software, helping bring research ...

RA Capital Management, LLC

Data Solution Engineer

Boston, MA · On-site

$124K - $149K/yr

... hcare, biotechnology, life sciences, and/or financial services experience strongly preferred ... Familiarity with APIs, integrations, and modern software engineering practices is a plus * Exposure ...

Edison

Forward Deployed AI Engineer

Boston, MA · On-site

$140 - $180/hr

... pharma and biotech - taking full ownership of how Edison's AI agents create value in their ... Requirements * 2+ years of professional software engineering experience, with a track record of ...

KG Tiger

Application Support Engineer

Natick, MA · On-site

It is a leading developer of mathematical computing software, Engineers and scientists worldwide ... biotech, semiconductor, etc. ABOUT KGTiger: A professional services consulting firm hired to ...

Vertex Pharmaceuticals

Senior AI DevOps Engineer

Boston, MA · On-site

$95K - $142K/yr

Working closely with software engineers, cloud architects, information security teams, and business ... Experience operating in pharmaceutical, biotechnology, healthcare, or other regulated environments.

Vrtx

Senior AI DevOps Engineer

Boston, MA · Hybrid

$95K - $142K/yr

Working closely with software engineers, cloud architects, information security teams, and business ... Experience operating in pharmaceutical, biotechnology, healthcare, or other regulated environments.

Prime Medicine

Informatics Engineer

Cambridge, MA · On-site

Translate scientific requirements into reliable, maintainable software, helping bring research ... such as biotech, pharma, healthtech, clinical informatics, scientific instrumentation, or ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively ... software engineering best practices • Strong problem-solving skills and ability to work ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively ... software engineering best practices • Strong problem-solving skills and ability to work ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively ... software engineering best practices • Strong problem-solving skills and ability to work ...

Manifold Bio

AI/ML Research Engineer

Boston, MA · On-site

Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively ... software engineering best practices • Strong problem-solving skills and ability to work ...

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All JobsBiotech Software Engineer JobsBiotech Software Engineer Jobs in Boston, MA

Biotech Software Engineer information

See Boston, MA salary details

$69K

$160.3K

$223.2K

How much do biotech software engineer jobs pay per year?

As of Aug 27, 2026, the average yearly pay for biotech software engineer in Boston, MA is $160,261.00, according to ZipRecruiter salary data. Most workers in this role earn between $130,400.00 and $187,900.00 per year, depending on experience, location, and employer.

What is a biotech software engineer?

A Biotech Software Engineer develops software solutions for the biotechnology industry, enabling research, data analysis, and automation in fields like genomics, bioinformatics, and drug discovery. They work with scientists to design algorithms, manage biological data, and create applications that support experiments and workflows. This role requires expertise in programming, cloud computing, and biological sciences to bridge the gap between technology and life sciences.

What does a biotech software engineer do?

As a Biotech Software Engineer, you'll often develop and maintain software tools for analyzing biological data, automate laboratory workflows, or create user-friendly interfaces for scientific researchers. Your daily tasks might include writing code, troubleshooting algorithms, reviewing scientific data, and collaborating closely with biologists, data scientists, and laboratory technicians. Depending on the company, you may be involved in developing cloud-based platforms, integrating new laboratory hardware, or ensuring software compliance with industry regulations. This dynamic and collaborative environment means your work directly impacts ongoing research and helps accelerate scientific discoveries in the biotech sector.

What are the key skills and qualifications needed to thrive as a biotech software engineer?

To thrive as a Biotech Software Engineer, you need a solid background in computer science or software engineering, coupled with an understanding of biology, genetics, or related life sciences. Familiarity with programming languages such as Python or Java, experience using bioinformatics tools (like BLAST or Bioconductor), and, in some settings, knowledge of regulatory standards are highly valuable. Strong problem-solving abilities, effective communication, and the ability to work well in interdisciplinary teams distinguish top performers in this field. These skills are crucial for building reliable software solutions that support scientific discovery and innovation in biotechnology organizations.

What are the most commonly searched types of Biotech Software Engineer jobs in Boston, MA?

The most popular types of Biotech Software Engineer jobs in Boston, MA are:

What are popular job titles related to Biotech Software Engineer jobs in Boston, MA?

For Biotech Software Engineer jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Biotech Software Engineer jobs in Boston, MA look for?

The top searched job categories for Biotech Software Engineer jobs in Boston, MA are:

What cities near Boston, MA are hiring for Biotech Software Engineer jobs?

Cities near Boston, MA with the most Biotech Software Engineer job openings:

Biotech Software Engineer jobs near you
Infographic showing various Biotech Software Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 84% Full Time, 12% Part Time, and 4% Contract. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution, with an average salary of $160,261 per year, or $77 per hour.

Informatics Engineer

Prime Medicine

Cambridge, MA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 17 days ago

Job description

Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit www.primemedicine.com.
About the role
We're hiring an Informatics Engineer to build the scientific data and computing platform that powers Prime Medicine's gene editing programs.
You will work in close partnership with our computational biology team and our cloud infrastructure team. The role suits someone who's comfortable owning a platform end-to-end, building the engineering foundations that scientists across the organization rely on, including data pipelines and APIs through to AI-enabled internal tooling. Your engineering judgment about what to build and how to build it will shape how Prime Medicine works with scientific data day-to-day.
What you'll do
  • Design and build the data platform connecting NGS instruments, laboratory informatics systems (Benchling), and AWS cloud compute; covering automated ingestion, provenance tracking, scalable storage, and observability.
  • Build production-grade APIs, SDKs, and internal tools that bring genomic data and analytical capabilities to scientists across the organization.
  • Build the orchestration layer for the automated, event-triggered execution of our scientific pipelines. The pipelines themselves (amplicon-seq, off-target analysis, and others) are co-developed with our computational biology team; you'll own how they run, scale, and integrate.
  • Ship AI-powered and agentic capabilities such as RAG over internal scientific data, agentic workflows with human-in-the-loop review, and internal copilots that streamline routine workflows across the organization connecting both science and business needs.
  • Build integrations across the scientific tool chain so data moves reliably between ELNs, LIMS, instrument software, and cloud compute.
  • Translate scientific requirements into reliable, maintainable software, helping bring research prototypes into production-grade systems.
  • Partner with computational biologists, lab scientists, and our cloud-support team to continuously improve platform performance, cost, and reliability.

What we're looking for
This is an Infrastructure engineering focused role, well suited to candidates whose primary background is software engineering, data engineering, or scientific platform engineering, with a strong interest in applying those skills to scientific problems.
Requirements:
  • 5+ years of full-time engineering experience (3+ for those with an MS or PhD) in production environments.
  • Strong Python programming skills.
  • Production AWS experience with depth in event-driven, cloud-native architectures, including AWS Lambda, EventBridge (or comparable event-routing infrastructure), and Infrastructure as Code with Terraform or CDK.
  • Docker / containerization, Git-based workflows, CI/CD, code review, and testing code in DEV/TEST environments before deploying to production.
  • A track record of building integrations and automations. Experience in a life-science related industry involving scientific or regulated data, such as biotech, pharma, healthtech, clinical informatics, scientific instrumentation, or agricultural genomics.

Nice to have
  • NGS expertise. Knowledge of NGS technology, workflows and pipeline architecture is strongly preferred.
  • Hands-on workflow orchestration experience. Familiarity with Nextflow/NextFlow Tower/Seqera Platform preferred.
  • Laboratory informatics experience with Benchling or comparable ELN/LIMS, as an operator, builder, or administrator.
  • AI / LLM tooling and agentic systems (LangChain, LangGraph, MCPs, RAG architectures).
  • Gene editing familiarity: CRISPR, base editing, prime editing.
  • GxP / 21 CFR Part 11 / regulated-software experience.
  • Plotly Dash, Streamlit, Spotfire, Retool, or similar tools for internal apps and data visualizations.
  • Experience managing or querying relational databases (PostgreSQL, MSSQL).

Interview process
The process includes a recruiter conversation, a hiring manager interview, and a small panel that includes computational biology, engineering, and wet lab partners. A Python coding exercise is part of the process
Logistics and policy
  • Hybrid with office in Cambridge, MA. We are not currently able to sponsor visas. US work authorization at the time of application is required.
  • Competitive base salary, equity, and standard benefits.

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus) and an annual long-term incentive award (e.g., equity).
Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits-including medical, dental, vision, life insurance, a 401(k) match, and equity programs-along with generous paid time off, wellness days, and company-wide recharge breaks.
Our commitment to employee well-being reflects our belief that when we care for our people, we strengthen our ability to put patients first and make meaningful impact together.
U.S. Pay Range
$134,000-$163,000 USD
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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