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Biotech Software Engineer Jobs in California (NOW HIRING)

AgreeYa Solutions

Software Engineer II

Redwood City, CA

$119K - $163K/yr

Software Engineer II (P3) - Production AI (Metrics & Analytics) AgreeYa is a global Systems ... Pharma & Biotech, Retail, Client, and others. Please visit us at www.agreeya.com for more ...

AgreeYa Solutions

Software Engineer II

Los Angeles, CA

$105K - $143K/yr

Software Engineer II (P3) - Production AI (Metrics & Analytics) AgreeYa is a global Systems ... Pharma & Biotech, Retail, Client, and others. Please visit us at www.agreeya.com for more ...

Mithrl

Senior Software Engineer

San Francisco, CA

$144K - $190K/yr

Required Qualifications * 7+ years of professional software engineering experience * Strong full ... Exposure to biotech, life sciences, or R&D workflows What You Will Love At Mithrl * High ownership ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

Strong understanding of system design, software architecture, and engineering best practices ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

Strong understanding of system design, software architecture, and engineering best practices ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

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All JobsBiotech Software Engineer JobsBiotech Software Engineer Jobs in California

Biotech Software Engineer information

See California salary details

$62.7K

$145.6K

$202.8K

How much do biotech software engineer jobs pay per year?

As of Jun 12, 2026, the average yearly pay for biotech software engineer in California is $145,592.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,400.00 and $170,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Biotech Software Engineer position, and why are they important?

To thrive as a Biotech Software Engineer, you need a solid background in computer science or software engineering, coupled with an understanding of biology, genetics, or related life sciences. Familiarity with programming languages such as Python or Java, experience using bioinformatics tools (like BLAST or Bioconductor), and, in some settings, knowledge of regulatory standards are highly valuable. Strong problem-solving abilities, effective communication, and the ability to work well in interdisciplinary teams distinguish top performers in this field. These skills are crucial for building reliable software solutions that support scientific discovery and innovation in biotechnology organizations.

What are some typical projects or daily tasks for a Biotech Software Engineer?

As a Biotech Software Engineer, you'll often develop and maintain software tools for analyzing biological data, automate laboratory workflows, or create user-friendly interfaces for scientific researchers. Your daily tasks might include writing code, troubleshooting algorithms, reviewing scientific data, and collaborating closely with biologists, data scientists, and laboratory technicians. Depending on the company, you may be involved in developing cloud-based platforms, integrating new laboratory hardware, or ensuring software compliance with industry regulations. This dynamic and collaborative environment means your work directly impacts ongoing research and helps accelerate scientific discoveries in the biotech sector.

What is a Biotech Software Engineer job?

A Biotech Software Engineer develops software solutions for the biotechnology industry, enabling research, data analysis, and automation in fields like genomics, bioinformatics, and drug discovery. They work with scientists to design algorithms, manage biological data, and create applications that support experiments and workflows. This role requires expertise in programming, cloud computing, and biological sciences to bridge the gap between technology and life sciences.

What are the most commonly searched types of Biotech Software Engineer jobs in California? The most popular types of Biotech Software Engineer jobs in California are:
What are popular job titles related to Biotech Software Engineer jobs in California? For Biotech Software Engineer jobs in California, the most frequently searched job titles are:
What job categories do people searching Biotech Software Engineer jobs in California look for? The top searched job categories for Biotech Software Engineer jobs in California are:
What cities in California are hiring for Biotech Software Engineer jobs? Cities in California with the most Biotech Software Engineer job openings:
Biotech Software Engineer jobs near you
Software Engineer (SWE I / SWE II)

Software Engineer (SWE I / SWE II)

BigHat Biosciences

San Mateo, CA • On-site

$135K - $175K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 17 days ago

Job description

The role: BigHat Biosciences is looking for a Software Engineer to join our Lab Systems team. This role is designed for engineers with several years of experience building and supporting production software who are excited to grow their technical scope and domain impact. You will work closely with engineers, product partners, and laboratory scientists to build and evolve internal software systems that support the design, build, and testing of therapeutic antibodies at scale.
Depending on experience and demonstrated impact, this role may be leveled as Software Engineer I (SWE I) or Software Engineer II (SWE II). Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
  • Design, implement, test, and maintain features in BigHat's internally developed, cloud-based LIMS+ platform.
  • Work independently on well-scoped features and improvements, following work through implementation, testing, and release.
  • Collaborate closely with cross-functional partners (scientists, product owners, and other engineers) to translate real-world lab workflows into reliable software.
  • Participate actively in engineering ceremonies, technical discussions, and code reviews.
  • Own the quality and outcomes of your work, including debugging, test failures, and production issues.
  • Continue developing technical depth in the codebase, infrastructure, and systems that support our applications.
This role reports to the Lab Systems Lead and works closely with the Lab Systems Product Owner, with responsibilities that impact teams across BigHat.
  • Build high-quality software across front-end (UI/UX) and back-end systems, aligned with product and user needs.
  • Read and understand PRDs and technical designs, contributing questions and implementation ideas.
  • Write and maintain automated tests to ensure correctness, reliability, and maintainability.
  • Participate constructively in code reviews; at the SWE II level, regularly review others' code and provide thoughtful feedback.
  • Debug and troubleshoot complex issues in production and development environments.
  • Contribute to improving internal engineering practices, documentation, and tooling.
About You
  • You have experience contributing to and owning work in a production software environment.
  • You are comfortable working independently on small to medium features and improvements.
  • You communicate clearly about progress, risks, and tradeoffs, and collaborate effectively with peers and partners.
  • You take ownership of your work and follow issues through to resolution.
  • You are curious and motivated by building software that supports real users doing complex work.
Experience
  • 3-5 years of professional software engineering experience building production systems
     OR
  • 2+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.
Relevant Tech / Skills

Experience with some (not necessarily all) of the following:
  • TypeScript, React, Material-UI, Vega
  • Python 3, SQLAlchemy
  • RESTful API design
  • AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
  • Relational databases (e.g., PostgreSQL)
  • Pandas
  • PyTorch or other ML frameworks (nice to have, not required)
The salary estimated for this position is $135,000 - $175,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match 
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

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