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Biotech Software Engineer Jobs in Berkeley, CA (NOW HIRING)

BigHat Biosciences

Senior Software Engineer

San Mateo, CA · On-site

$139K - $183K/yr

Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience. *At BigHat we believe in titles that ...

RheoSense, Inc.

Software Engineer

San Ramon, CA · On-site

$120K - $155K/yr

... across biotechnology, pharmaceuticals, materials science, and advanced manufacturing. We are ... Software Engineer Corporate Office: San Ramon, California Relocation Assistance: No (Local ...

BigHat Biosciences

Senior Software Engineer

San Mateo, CA · On-site

$139K - $184K/yr

Job Summary : BigHat Biosciences is looking for a Senior Software Engineer to join their ... biotech, life sciences, laboratory environments, or scientific software, where domain knowledge ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

Strong understanding of system design, software architecture, and engineering best practices ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

Strong understanding of system design, software architecture, and engineering best practices ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

LatchBio

Software Engineer

San Francisco, CA · On-site

$180K - $250K/yr

Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI ... We need engineers to build the infrastructure that powers our benchmarking pipeline - data ...

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All JobsBiotech Software Engineer JobsBiotech Software Engineer Jobs in Berkeley, CA

Biotech Software Engineer information

See Berkeley, CA salary details

$77.8K

$180.6K

$251.6K

How much do biotech software engineer jobs pay per year?

As of Jul 26, 2026, the average yearly pay for biotech software engineer in Berkeley, CA is $180,634.00, according to ZipRecruiter salary data. Most workers in this role earn between $146,900.00 and $211,800.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Biotech Software Engineer position, and why are they important?

To thrive as a Biotech Software Engineer, you need a solid background in computer science or software engineering, coupled with an understanding of biology, genetics, or related life sciences. Familiarity with programming languages such as Python or Java, experience using bioinformatics tools (like BLAST or Bioconductor), and, in some settings, knowledge of regulatory standards are highly valuable. Strong problem-solving abilities, effective communication, and the ability to work well in interdisciplinary teams distinguish top performers in this field. These skills are crucial for building reliable software solutions that support scientific discovery and innovation in biotechnology organizations.

What engineers make $500,000?

Senior biotech software engineers with extensive experience, specialized skills in data analysis, machine learning, or bioinformatics, and often working in leadership roles or at large biotech firms can earn $500,000 or more annually. High compensation may also include bonuses, stock options, or profit sharing, especially in competitive or rapidly growing companies.

What are some typical projects or daily tasks for a Biotech Software Engineer?

As a Biotech Software Engineer, you'll often develop and maintain software tools for analyzing biological data, automate laboratory workflows, or create user-friendly interfaces for scientific researchers. Your daily tasks might include writing code, troubleshooting algorithms, reviewing scientific data, and collaborating closely with biologists, data scientists, and laboratory technicians. Depending on the company, you may be involved in developing cloud-based platforms, integrating new laboratory hardware, or ensuring software compliance with industry regulations. This dynamic and collaborative environment means your work directly impacts ongoing research and helps accelerate scientific discoveries in the biotech sector.

Will AI replace biotechnologists?

Biotech software engineers and biotechnologists perform complementary roles; AI can automate certain tasks like data analysis and modeling but is unlikely to fully replace the expertise, creativity, and decision-making skills required in biotechnology. Human oversight remains essential for experimental design, interpretation, and ethical considerations in the field.

What is a biotech software engineer?

A biotech software engineer develops software applications and tools to support biological research, healthcare, and pharmaceutical development. They often work with data analysis, automation, and laboratory systems, requiring skills in programming, bioinformatics, and understanding of biological processes.

What is a Biotech Software Engineer job?

A Biotech Software Engineer develops software solutions for the biotechnology industry, enabling research, data analysis, and automation in fields like genomics, bioinformatics, and drug discovery. They work with scientists to design algorithms, manage biological data, and create applications that support experiments and workflows. This role requires expertise in programming, cloud computing, and biological sciences to bridge the gap between technology and life sciences.

Can you make $500,000 as a software engineer?

Biotech software engineers typically earn between $80,000 and $150,000 annually, with higher salaries possible for senior roles or those with specialized skills like data analysis or machine learning. Reaching a $500,000 salary usually requires extensive experience, leadership positions, or working in high-paying industries or companies. Such compensation levels are uncommon for standard biotech software engineering roles.
What are the most commonly searched types of Biotech Software Engineer jobs in Berkeley, CA? The most popular types of Biotech Software Engineer jobs in Berkeley, CA are:
What are popular job titles related to Biotech Software Engineer jobs in Berkeley, CA? For Biotech Software Engineer jobs in Berkeley, CA, the most frequently searched job titles are:
What job categories do people searching Biotech Software Engineer jobs in Berkeley, CA look for? The top searched job categories for Biotech Software Engineer jobs in Berkeley, CA are:
What cities near Berkeley, CA are hiring for Biotech Software Engineer jobs? Cities near Berkeley, CA with the most Biotech Software Engineer job openings:
Biotech Software Engineer jobs near you
Infographic showing various Biotech Software Engineer job openings in Berkeley, CA as of July 2026, with employment types broken down into 89% Full Time, 3% Part Time, 1% Temporary, and 7% Contract. Highlights an 83% Physical, 3% Hybrid, and 14% Remote job distribution, with an average salary of $180,634 per year, or $86.8 per hour.
Senior Software Engineer

Senior Software Engineer

BigHat Biosciences

San Mateo, CA

$19K - $215K/mo

Full-time

Medical, Dental, Vision, Retirement

Posted yesterday

Job description

The role: BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject-matter expert, lead epics end-to-end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.
This role is leveled as Senior Software Engineer I. At this level, you operate as a subject-matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.
  • Lead projects end-to-end, from PRD through implementation, testing, release, and validation against the customer success metric.
  • Own one or more major areas of BigHat's internally developed, cloud-based platform as a subject-matter expert, and serve as a cross-team and cross-org resource for those areas.
  • Take on net-new, 0-to-1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.
  • Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real-world lab workflows into reliable software, and to iterate on success metrics.
  • Operate and run engineering processes: PRD reviews, stand-ups, PR approvals, and other team ceremonies.
  • Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.
  • Drive technical depth across the codebase, infrastructure, and systems, and actively improve the design and architectural principles the team works within.
  • Design and build high-quality software across front-end (UI/UX) and back-end systems, with system-level expertise in the databases, AWS services, runtimes, and processes that underpin them.
  • Lead and review technical designs and PRDs; contribute architectural direction and surface risks and tradeoffs early.
  • Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.
  • Run code reviews as a routine approver, providing thoughtful, high-leverage feedback that develops other engineers.
  • Diagnose and resolve complex issues across production and development environments, including across system and environment boundaries.
  • Improve internal engineering practices, documentation, tooling, and architecture; help set and transmit appropriate urgency in partnership with engineering leaders.
About You
  • You have a track record of owning features and epics end to end in a production software environment.
  • You are an SME in at least one significant technical area and are reaching to master new ones.
  • You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.
  • You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.
  • You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.
  • You are motivated by building software that supports real users doing complex, high-stakes scientific work.
  • You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.
Experience
  • 7+ years of professional software engineering experience building and owning production systems, including demonstrated end-to-end ownership of features or epics, OR
  • 5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.
Relevant Tech / Skills
Depth in several of the following, with the ability to make and improve system- and architecture-level decisions:
  • TypeScript, React, Material-UI, Vega
  • Python 3, SQLAlchemy
  • RESTful API design
  • AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
  • Relational databases (e.g., PostgreSQL), including schema and query design
  • Pandas
  • PyTorch or other ML frameworks (nice to have, not required)
The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match 
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

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