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Bioanalytical Mass Spectrometry Jobs (NOW HIRING)

Genentech

Principal Scientist

South San Francisco, CA · On-site

$143K - $265K/yr

Perform mass spectrometry data processing and statistical analysis; build or leverage Generative AI ... Oversee rigorous bioanalytical quality control using common industry practices and critical ...

Genentech

Principal Scientist

San Francisco, CA · On-site

$143.20 - $265.90/hr

Perform mass spectrometry data processing and statistical analysis; build or leverage Generative AI ... Oversee rigorous bioanalytical quality control using common industry practices and critical ...

Genentech

Principal Scientist

South San Francisco, CA · On-site

$143.20 - $265.90/hr

Perform mass spectrometry data processing and statistical analysis; build or leverage Generative AI ... Oversee rigorous bioanalytical quality control using common industry practices and critical ...

Discovery Life Sciences LLC

Senior Scientist

Malden, MA

$95K - $130K/yr

Design and execute qualitative bioanalytical strategies supporting regulated and non-regulated ... Interpret complex mass spectrometry and MS/MS fragmentation data. * Characterize metabolites and ...

Discovery Life Sciences

Senior Scientist

Malden, MA

$95K - $130K/yr

Design and execute qualitative bioanalytical strategies supporting regulated and non-regulated ... Interpret complex mass spectrometry and MS/MS fragmentation data. * Characterize metabolites and ...

Discovery Life Sciences

Senior Scientist

Malden, MA · On-site

$95K - $130K/yr

Design and execute qualitative bioanalytical strategies supporting regulated and non-regulated ... Interpret complex mass spectrometry and MS/MS fragmentation data. * Characterize metabolites and ...

University of Michigan

RESEARCH FELLOW

Ann Arbor, MI · On-site

... mass spectrometry imaging of small molecules, endogenous metabolites, lipids, proteins on tissue sections. What You'll Do * LC-MS bioanalysis method development, validation, and samples analysis to ...

MSD

Scientist, Pharmacokinetics

West Point, PA · On-site

$87K - $137K/yr

Qualitative bioanalysis using LC-HRMS (Liquid chromatography high resolution mass spectrometry), including assay development. * Generation, interpretation, and documentation of high-quality ADME/DMPK ...

Parexel

$34.50 - $43.25/hr

Familiarity with the operation of chromatographic tandem mass spectrometric and ligand binding assays including bioanalysis of large molecules by mass spectrometry (or other comparable bioanalytical ...

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How much do bioanalytical mass spectrometry jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for bioanalytical mass spectrometry in the United States is $22.62, according to ZipRecruiter salary data. Most workers in this role earn between $18.51 and $24.04 per hour, depending on experience, location, and employer.

What is the difference between Bioanalytical Mass Spectrometry vs Analytical Chemist?

AspectBioanalytical Mass SpectrometryAnalytical Chemist
CredentialsBachelor's or Master's in Chemistry, Biochemistry, or related fields; certifications in mass spectrometryBachelor's or Master's in Chemistry or related fields; certifications vary
Work EnvironmentLaboratories focused on drug development, pharmacokinetics, or clinical researchGeneral laboratories, quality control, research and development
Industry UsagePharmaceutical, biotech, clinical researchPharmaceutical, environmental, food testing, academia

Bioanalytical Mass Spectrometry specialists focus on analyzing biological samples using mass spectrometry techniques, often within pharmaceutical and clinical settings. Analytical Chemists have broader roles in chemical analysis across various industries. While both roles require chemistry knowledge, bioanalytical mass spectrometry professionals specialize in advanced instrumentation and biological sample analysis, making their skills more specific to bioanalysis applications.

What is bioanalytical mass spectrometry?

Bioanalytical mass spectrometry is a scientific technique used to identify and quantify chemicals, such as drugs and biomolecules, in biological samples. It combines the principles of mass spectrometry with bioanalytical chemistry to analyze complex biological matrices like blood, urine, or tissue extracts. This method is essential in pharmaceutical research, clinical diagnostics, and biomarker discovery due to its high sensitivity, specificity, and accuracy.

What are some typical challenges faced when working in bioanalytical mass spectrometry, and how can they be addressed?

Professionals in bioanalytical mass spectrometry often encounter challenges such as matrix effects, sample preparation complexities, and data interpretation of complex biological samples. Addressing these challenges involves optimizing sample clean-up procedures, regularly calibrating and maintaining instruments, and collaborating closely with colleagues in method development and validation. Staying current with new analytical techniques and software tools can also help in resolving technical issues and ensuring reliable, high-quality data for regulatory submissions or research projects.

What are the key skills and qualifications needed to thrive in bioanalytical mass spectrometry, and why are they important?

To thrive in Bioanalytical Mass Spectrometry, you need a solid background in analytical chemistry, biochemistry, and quantitative analysis, often supported by a relevant degree (such as a BSc, MSc, or PhD). Proficiency with mass spectrometry instruments (e.g., LC-MS/MS), chromatography systems, and specialized data analysis software is essential, and certifications in laboratory safety or GLP can be advantageous. Attention to detail, critical thinking, and strong problem-solving abilities help you interpret complex datasets and troubleshoot technical issues effectively. These skills are crucial for producing accurate, reproducible results that drive scientific discovery and support regulatory compliance in pharmaceutical, clinical, or research environments.
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Bioanalytical Mass Spectrometry jobs near you
Infographic showing various Bioanalytical Mass Spectrometry job openings in the United States as of August 2026, with employment types broken down into 70% Full Time, 29% Part Time, and 1% Contract. Highlights an 94% Physical, 3% Hybrid, and 3% Remote job distribution, with an average salary of $47,050 per year, or $22.6 per hour.

Scientist I - Mass Spec Development (LC-MS/MS)

KCAS Bio

Kansas City, MO

Full-time

Re-posted 28 days ago

Job description

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by learning and applying your knowledge in bioanalytical and scientific principles to support study execution and development activities under the guidance of senior scientists. You will begin building your foundation in assessing data integrity and troubleshooting with support.

Our Mass Spec Bioanalysis Development team uses LCMS (Liquid Chromatography Mass Spectrometry) techniques to conduct sophisticated sample preparation to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:
  • Execute assigned portions of studies including sample preparation (extractions, enrichments/affinity capture, digestions) and LCMS analysis under supervision
  • Support method development and qualification activities by following established protocols
  • Perform routine data processing and assist in preparing data summaries
  • Troubleshoot basic technical issues with guidance
  • Maintain accurate documentation in compliance with study protocols, SOPs & regulatory requirements
  • Ensure proper sample identification, handling, and tracking
  • Communicate progress and escalate issues to senior staff as needed
  • Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values
To qualify for this role, you will have:
  • Bachelor’s or master’s in chemistry, Biochemistry or chemical/biochemical engineering, or related field with 2+ years of experience with LC-MS/MS
  • Exposure to bioanalytical sample preparation and quantitative LC-MS/MS techniques (academic or industry)
  • Basic understanding of chromatographic principles and mass spectrometry
  • Experience with small molecule analysis; exposure to proteins and peptides is a plus
  • Familiarity with laboratory documentation and working in a structured or regulated environment is preferred
Depending on your background and qualifications, we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.  

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE
You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU’LL GET
Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio 

WHO WE ARE
We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to kcasrecruiting@kcasbio.com or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.
 
IND123

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.