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High Resolution Mass Spectrometry Jobs (NOW HIRING)

Stowers Institute

Scientist

Kansas City, MO · On-site

Demonstrated hands-on experience with native and/or top-down mass spectrometry of proteins and protein complexes. * Strong background in high-resolution MS instrumentation and protein-level ...

Battelle

Chemist

Atlanta, GA · On-site

Advanced high-resolution mass spectrometry (HRMS) and liquid chromatography (LC) experience * Knowledge of advanced sample preparation techniques * Experience in clinical method development * Basic ...

Battelle Memorial Institute

Chemist

Atlanta, GA · On-site

Advanced high-resolution mass spectrometry (HRMS) and liquid chromatography (LC) experience * Knowledge of advanced sample preparation techniques * Experience in clinical method development * Basic ...

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High Resolution Mass Spectrometry information

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$34K

$70.3K

$114.5K

How much do high resolution mass spectrometry jobs pay per year?

As of Jun 14, 2026, the average yearly pay for high resolution mass spectrometry in the United States is $70,345.00, according to ZipRecruiter salary data. Most workers in this role earn between $50,000.00 and $86,500.00 per year, depending on experience, location, and employer.

What are the typical day-to-day responsibilities for someone working in High Resolution Mass Spectrometry?

Professionals in High Resolution Mass Spectrometry are responsible for preparing samples, operating mass spectrometry instruments, performing method development, and interpreting complex analytical data. They often collaborate with colleagues in research, quality control, or product development to support broader scientific or manufacturing objectives. Daily tasks also include routine instrument maintenance, troubleshooting technical issues, and clearly documenting experimental results. Working in this role offers exposure to cutting-edge analytical technologies and provides opportunities to contribute to projects in pharmaceuticals, environmental science, or biotechnology.

What is a simile for high?

In the context of High Resolution Mass Spectrometry, 'high' can be compared to something that is elevated or at an advanced level, such as a mountain peak or a soaring bird, indicating superior resolution or sensitivity. This simile emphasizes the instrument's ability to detect and analyze very small differences in mass with precision. Understanding the 'high' resolution capabilities is essential for accurate identification of complex molecules in analytical chemistry.

What are synonyms for high?

In the context of high resolution mass spectrometry, synonyms for high include terms like elevated, advanced, or superior, which describe the level of detail or precision in the instrument's measurements. These terms emphasize the instrument's capability to distinguish between closely related molecular masses, often requiring specialized training and calibration. Understanding these synonyms helps in accurately communicating the instrument's performance in scientific and technical settings.

What are the key skills and qualifications needed to thrive in the High Resolution Mass Spectrometry position, and why are they important?

To thrive in High Resolution Mass Spectrometry, you need a solid background in analytical chemistry, experience with advanced mass spectrometry techniques, and typically a degree in chemistry, biochemistry, or a related field. Familiarity with instrumentation such as Orbitrap or time-of-flight mass spectrometers, data analysis software, and relevant laboratory certifications is highly valuable. Strong problem-solving skills, attention to detail, and effective communication help set candidates apart in this highly technical environment. These qualities are essential for producing accurate and reliable analytical results, ensuring safety, and collaborating effectively within research or quality assurance teams.

What is a High Resolution Mass Spectrometry job?

A High Resolution Mass Spectrometry (HRMS) job involves analyzing chemical compounds with high accuracy and precision using advanced mass spectrometers. Professionals in this role work in laboratories across industries like pharmaceuticals, environmental science, and forensics to identify and quantify complex molecules. Responsibilities may include sample preparation, data interpretation, instrument maintenance, and ensuring compliance with regulatory standards. Strong analytical skills and expertise in mass spectrometry techniques are essential for success in this field.

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What cities are hiring for High Resolution Mass Spectrometry jobs? Cities with the most High Resolution Mass Spectrometry job openings:
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High Resolution Mass Spectrometry jobs near you
Infographic showing various High Resolution Mass Spectrometry job openings in the United States as of June 2026, with employment types broken down into 13% Locum Tenens, 5% Full Time, 3% Contract, 74% Nights, and 5% Summer. Highlights an 89% Physical, 4% Hybrid, and 7% Remote job distribution, with an average salary of $70,345 per year, or $33.8 per hour.
Instrument Design Physicist - Mass Spectrometry

Instrument Design Physicist - Mass Spectrometry

Agilent

Santa Clara, CA • On-site

$205K - $321K/yr

Full-time

Posted 4 days ago

Agilent Technologies rating

8.1

Company rating: 8.1 out of 10

Based on 38 frontline employees who took The Breakroom Quiz

109th of 518 rated manufacturers

Job description

Job Description
Join a premier measurement company focused on improving the quality of life and the world around us by bringing great science to life. Agilent, a global leader in life sciences, diagnostics, and applied markets, is seeking an experienced Instrument Design Physicist with a focus on Mass Spectrometry to join an interdisciplinary team of scientists and engineers supporting new product development.
This role offers a compelling opportunity for an experienced instrument designer to lead, influence, and advance Agilent's Mass Spectrometry portfolio. In this position, you will leverage your scientific and engineering expertise, technical leadership, collaboration and communication skills, and industry knowledge to help define and execute the vision for Agilent's technology development in High-Resolution Mass Spectrometry.
Key Responsibilities
  • Initiate, design, and execute scientific research and development strategies to create devices, products, applications, and/or services related to mass spectrometry optics and overall instrument design.

  • Apply a wide range of scientific principles and concepts to inventions, products, and technical challenges, including ionization and ion optics, vacuum systems, ion detection systems, high-voltage power supplies, RF electrodes, and digitizer systems.

  • Investigate, evaluate, and test discoveries through experimentation and application of scientific knowledge.

  • Share knowledge and expertise with team members across functions and business divisions.

  • Troubleshoot equipment and products to validate data collection processes and resolve technical issues.

  • Maintain broad awareness of state-of-the-art principles, theories, and academic and industrial developments in mass spectrometry.

  • Contribute to scientific literature and professional forums, including publications, application notes, and presentations at conferences and symposia.

  • Participate in the development of patent applications and other intellectual property disclosures.

  • Interface with cross-functional teams (e.g., Marketing, Product Support, Manufacturing) and serve as an internal technical consultant.

  • Travel to manufacturing facilities to support new product development and resolve technical issues.

  • Visit customers to gather insights that inform product development and to support issue resolution.

  • Provide technical due diligence assessments, including intellectual property reviews, for technology licensing and acquisition opportunities.

Qualifications
  • PhD in Physics or a closely related scientific discipline.
  • Typically, at least 10+ years of relevant experience for entry to this level.
  • Demonstrated success in ion optics design, including optimization across multiple performance dimensions.
  • Deep understanding of and hands-on experience with Mass Spectrometry detector technologies, including MCP-based detectors.
  • Experience working with high-voltage power supplies and RF power supplies, including an understanding of performance characteristics that influence Mass Spectrometry system design and performance.
  • Practical experience with high-vacuum system design practices relevant to Mass Spectrometry applications.
  • Proficiency with simulation tools such as SIMION, ANSYS, or equivalent.
  • Strong Python programming capability.
  • Solid knowledge of relevant materials science concepts applicable to Mass Spectrometry systems.

Preferred Qualifications
  • Advanced or specialized experience leading scientific or technical development initiatives in Mass Spectrometry.
  • Demonstrated ability to influence system-level design decisions through cross-disciplinary technical expertise.

Additional Details
This job has a full time weekly schedule. Applications for this job will be accepted until at least March 27, 2026 or until the job is no longer posted.
The full-time equivalent pay range for this position is $205,920.00 - $321,750.00/yr plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: https://careers.agilent.com/locations
Agilent Technologies, Inc. is an Equal Employment Opportunity and merit-based employer that values individuals of all backgrounds at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases. Agilent Technologies, Inc., is committed to creating and maintaining an inclusive in the workplace where everyone is welcome, and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email job_posting@agilent.com or contact +1-262-754-5030. For more information about equal employment opportunity protections, please visit www.agilent.com/en/accessibility.
Travel Required:
Occasional
Shift:
Day
Duration:
No End Date
Job Function:
R&D

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