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Associate Clinical Trial Manager Jobs (NOW HIRING)

C4 Therapeutics Inc

Clinical Trial Manager

Watertown, MA · On-site

$138K - $153K/yr

In collaboration with the Clinical Operations leadership, develop, manage, and track clinical trial budgets including providing ongoing reporting and forecasting to finance (inclusive of site budget ...

ICON

Clinical Trial Manager

Raleigh, NC · On-site +1

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Clinical Trial Manager - Phase I oncology ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

Icon plc

Clinical Trial Manager

Philadelphia, PA

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Clinical Trial Manager - Phase I oncology ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

Kardigan

Clinical Trial Manager

Princeton, NJ · On-site

As a Clinical Trial Manager (CTM), you will be part of the Clinical Operations team reporting to the asset's Clinical Trial or Clinical Program Lead. This position will be responsible for the ...

Icon plc

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Clinical Trial Manager - Phase I oncology ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As ...

Frontier Medicines

Clinical Trial Manager

Boston, MA · Hybrid

$120K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

Frontier Medicines

Clinical Trial Manager

Boston, MA · On-site

$120K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance ...

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How much do associate clinical trial manager jobs pay per hour?

As of Aug 12, 2026, the average hourly pay for associate clinical trial manager in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

What are some common challenges faced by associate clinical trial managers when coordinating cross-functional teams?

Associate Clinical Trial Managers often encounter challenges related to aligning objectives and communication among cross-functional teams, such as regulatory, clinical operations, data management, and vendors. Managing timelines, ensuring all parties are updated on protocol changes, and resolving conflicts between departments can be complex, especially in a fast-paced environment. Proactive communication, attention to detail, and strong organizational skills are essential for overcoming these challenges and maintaining trial quality and compliance.

What does an associate clinical trial manager do?

An Associate Clinical Trial Manager assists in the planning, execution, and management of clinical trials to ensure they are conducted in accordance with regulatory guidelines and company protocols. They support the Clinical Trial Manager by coordinating study timelines, managing vendors and sites, and overseeing documentation and reporting. This role involves collaborating with cross-functional teams, identifying and resolving issues, and ensuring that trials meet quality and compliance standards. Associate Clinical Trial Managers play a key part in bringing new treatments to market efficiently and safely.

What is the difference between Associate Clinical Trial Manager vs Clinical Trial Coordinator?

AspectAssociate Clinical Trial ManagerClinical Trial Coordinator
ResponsibilitiesOversees trial operations, manages teams, ensures compliance, and supports trial planningCoordinates trial activities, manages documentation, schedules visits, and assists with data collection
Required CredentialsBachelor's degree, experience in clinical trials, knowledge of GCPBachelor's degree, experience in clinical settings, familiarity with trial procedures
Work EnvironmentTypically in clinical research settings, working closely with managers and teamsOften in clinical sites or research offices, supporting trial staff

The Associate Clinical Trial Manager and Clinical Trial Coordinator roles share similar educational backgrounds and work environments. However, the Associate Clinical Trial Manager has broader responsibilities, including overseeing trial operations and managing teams, while the Clinical Trial Coordinator focuses on day-to-day coordination and documentation tasks. Both roles are essential in clinical research, with the manager position having a higher level of oversight and strategic involvement.

What are the key skills and qualifications needed to thrive as an associate clinical trial manager?

To thrive as an Associate Clinical Trial Manager, you need a solid understanding of clinical trial processes, regulatory guidelines, and a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as GCP (Good Clinical Practice) are typically required. Strong organizational skills, attention to detail, and effective communication are essential soft skills for managing timelines and collaborating with multiple stakeholders. These skills and qualifications ensure clinical trials run smoothly, comply with regulations, and deliver reliable results.
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Associate Clinical Trial Manager jobs near you
Infographic showing various Associate Clinical Trial Manager job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 12% Part Time, and 1% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.

Clinical Trial Manager/Senior Clinical Trial Manager

Oruka Therapeutics

Waltham, MA • On-site

Full-time

Re-posted 4 days ago

Job description

About Us:
Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka's mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com
As we build our core team, we're seeking top talent in different functional areas who are not just looking for a job, but an opportunity to be part of something bigger. Someone who is passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.
Job Title: Clinical Trial Manager/Senior Clinical Trial Manager
Location: Hybrid 3 days/week if located near office in Waltham, MA or Menlo Park, CA will be required. Remote may be considered.
About Us:
Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka's mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com
As we build our core team, we're seeking top talent in different functional areas who are not just looking for a job, but an opportunity to be part of something bigger. Someone who is passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.
Role Overview:
Will ensure trial compliance, regulatory alignment, and operational efficiency while collaborating with cross-functional teams to advance Oruka's clinical pipeline. Independently manage the clinical trial by effectively planning and executing the study to ensure quality of deliverables within the specified budget and timeframe. May serve as the clinical functional lead and lead clinical trial initiatives for Oruka's cutting-edge dermatology treatments.
Key Responsibilities:
  • Clinical Trial Management:
    • Lead and manage multiple clinical trials from initiation through to completion, ensuring adherence to study timelines and budgets.
    • Collaborate with investigators, vendors, and cross-functional teams to ensure study execution and operational excellence.
    • Oversee the preparation and review of trial-related documentation, including protocols, informed consent forms (ICFs), case report forms (CRFs), and study reports.
    • In partnership with Program Management, develop and drive cross functional study timelines related to trial setup and execution.
  • Team Leadership:
    • Drive the cross functional internal study team ensuring appropriate alignment, risk management and coordination across all participating functions.
    • Successfully interface with Data Management, Biostatistics and Clinical Development to ensure seamless monitoring and data cleaning initiatives to meet study deliverables and timelines
    • Foster a collaborative team environment focused on operational efficiency and continuous improvement.
  • Regulatory and Compliance Oversight:
    • Ensure that clinical trials are conducted in compliance with all applicable regulations, including FDA, EMA, and ICH-GCP guidelines.
    • Support the preparation and submission of clinical trial applications, including INDs, NDAs, and other regulatory documents with functional leads.
    • Manage interactions with Regulatory Affairs and external vendors to ensure timely submissions and approvals.
  • Budget and Resource Management:
    • Develop and manage clinical trial budgets, ensuring efficient use of resources and timely financial reporting.
    • Monitor and control trial costs to ensure alignment with project forecasts and company objectives.
    • Negotiate contracts and budgets with clinical vendors and investigators.
  • Vendor and Site Management:
    • Oversee the selection and management of clinical vendors (CROs, laboratories, etc.) and ensure they meet performance expectations.
    • Develop strong relationships with clinical sites and external partners to ensure aggressive site startup, high-quality data collection and trial conduct.
    • Perform risk assessment and management, addressing issues proactively to mitigate operational issues.

Qualifications:
  • Bachelor's or Master's degree in life sciences or a related field.
  • 5-7+ years of experience in clinical operations, with a focus on managing complex clinical trials.
  • Expertise in GCP and regulatory requirements.
  • Strong leadership and team management skills.

Compensation:
  • An appropriate financial package will be developed for the successful candidate to include a competitive base salary and equity, with a performance-related bonus opportunity.
  • The anticipated salary range for Manager level is $146,000 - $161,000 and Sr. Manager level is $161,000 - $187,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Oruka is a multi-state employer and this salary range may not reflect positions that work in other states.

Job Location:
  • Hybrid 3 days/week if located near office in Waltham, MA or Menlo Park, CA will be required. Remote may be considered.

We're looking forward to hearing how you can contribute to our team and mission. Join us in shaping the future of our company and making a real impact every day.
Salary Range for the Role
$146,000-$187,000 USD
What We Offer:
  • A chance to be part of a vibrant startup culture where your work can directly impact bringing new medicines to patients.
  • Competitive salary and benefits package.
  • A supportive and inclusive team environment where everyone is encouraged to bring their authentic selves to work.
  • Opportunities for professional growth and development.

Apply