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$30.5K

$97.6K

$153.5K

How much do api manufacturing jobs pay per year?

As of Aug 7, 2026, the average yearly pay for api manufacturing in the United States is $97,556.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,000.00 and $120,500.00 per year, depending on experience, location, and employer.

What kinds of teams or departments do api manufacturing professionals typically collaborate with?

API Manufacturing professionals often work closely with quality assurance, process development, engineering, and regulatory affairs teams to ensure safe and compliant production of pharmaceutical ingredients. Daily responsibilities may involve coordinating with maintenance staff for equipment upkeep and troubleshooting, as well as working with quality control analysts to monitor product specifications. This collaborative environment fosters continuous improvement and adherence to strict industry standards, making strong communication and teamwork vital. Joining an API manufacturing team often provides exposure to cross-functional projects and potential pathways for advancement into supervisory or technical specialist roles.

What are the key skills and qualifications needed to thrive in api manufacturing?

To thrive in API Manufacturing, you need a solid understanding of chemical processes, current Good Manufacturing Practices (cGMP), and safety regulations, typically supported by a degree in chemistry, chemical engineering, or a related field. Experience with process control systems, laboratory information management systems (LIMS), and relevant safety certifications such as OSHA are essential. Strong attention to detail, teamwork, and problem-solving skills are valued soft skills in this setting. These capabilities ensure production efficiency, regulatory compliance, and safety in the manufacture of active pharmaceutical ingredients.

What is an api manufacturing?

An API Manufacturing job involves the production of Active Pharmaceutical Ingredients (APIs), which are the key components in medications. Professionals in this field oversee chemical synthesis, purification, and quality control processes to ensure that APIs meet regulatory and safety standards. They work in pharmaceutical manufacturing facilities, following strict guidelines set by regulatory bodies like the FDA and EMA. The role often includes maintaining Good Manufacturing Practices (GMP), troubleshooting production issues, and optimizing processes for efficiency and quality.

More about Api Manufacturing jobs
What are the most commonly searched types of Api Manufacturing jobs? The most popular types of Api Manufacturing jobs are:
What states have the most Api Manufacturing jobs? States with the most job openings for Api Manufacturing jobs include:
What job categories do people searching Api Manufacturing jobs look for? The top searched job categories for Api Manufacturing jobs are:
Api Manufacturing jobs near you
Infographic showing various Api Manufacturing job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 4% Part Time, 1% Temporary, 4% Contract, and 3% Nights. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $97,556 per year, or $46.9 per hour.

API Manufacturing Process Safety Engineer

Phlow Corp

Petersburg, VA • On-site

$100K - $150K/yr

Full-time

Medical, Life, Retirement, PTO

Re-posted 10 days ago

Job description

Phlow Corp is seeking an API Manufacturing Process Safety Engineer to own and build the API Manufacturing Process Safety program from the ground up for small-molecule API manufacturing at the Petersburg, VA campus. This position is directly responsible for the process safety activities associated with technology transfer, process design, and GMP startup, and works hand in hand with the Tech Transfer team and the GMP Manufacturing Operations team to ensure safe, compliant, and reliable operations. The role leads process safety assessments, Management of Change (MOC), and the implementation and verification of safeguards in GMP manufacturing.
Requirements
Essential Job Duties & Responsibilities
  • Build, implement, and continually improve the API Process Safety program in alignment with OSHA PSM, EPA requirements, and Phlow procedures.
  • Own and lead PFMEAs, PHAs, and PSSRs for new and existing API processes; translate outcomes into practical engineered and administrative controls for GMP operations.
  • Identify and control hazards typical to API operations (e.g., exotherms, overpressure, vacuum collapse, flammable/toxic releases, static, dust deflagration) and ensure safeguards are in place and effective.
  • Coordinate thermal hazard characterization (e.g., DSC/ARC/RC1) and ensure data are integrated into equipment design, operating limits, automation strategies, interlocks, and procedures.
  • Develop and support relief and vent strategies (PSVs/rupture discs, vent sizing, scrubbers/containment) and contribute to LOPA/SIL evaluations and verification of assumptions.
  • Own the process safety portion of the MOC process by evaluating risk impacts, defining required safeguards, and confirming PSI updates, training, and startup readiness.
  • Define mechanical integrity expectations for critical protective systems and instrumented functions; work closely with Maintenance and Engineering to prioritize and validate testing.
  • Lead or participate in incident and near-miss investigations related to process and equipment; perform root cause analysis and track corrective/preventive actions to closure.
  • Develop and deliver training and coaching for employees and contractors on process safety and life safety requirements related to API manufacturing.
  • Collaborate closely with Tech Transfer, GMP Manufacturing GMP Manufacturing Operations, Process Engineering, Quality & Regulatory, Facility Security, and local emergency responders to support drills, pre-incident planning, and safe execution of campaigns.

Requirements:
  • Bachelor's degree in Chemical Engineering or a closely related engineering discipline.
  • Experience in process safety, chemical engineering, or EHS in manufacturing (pharma/API or chemical processing preferred).
  • Practical experience with exothermic/reactive chemistry, overpressure protection, or cryogenic/flammable systems.
  • Working knowledge of OSHA/EPA regulations and core PSM elements (PHA/HAZOP, LOPA/SIL concepts, MOC, PSSR, incident investigation).
  • Proficiency with process safety tools and documentation (PSI, risk assessments, action tracking).
  • Strong analytical and problem-solving skills with the ability to collaborate in cross-functional teams.
  • Ability to work in a fast-paced environment with regular field presence in manufacturing areas.

Competencies/Skills:
  • Solid technical proficiency in process safety methods and engineering fundamentals.
  • Ability to perform structured risk assessments and recommend practical mitigation strategies.
  • Effective communication and interpersonal skills at all organizational levels.
  • Strong organizational skills and the ability to manage multiple tasks and priorities.
  • Continuous improvement mindset and attention to detail.

Working Conditions:
  • Work environment includes GMP manufacturing suites, technical areas, and utilities with potential exposure to chemical materials and elevated noise.
  • Must maintain a high level of awareness for personnel and equipment safety.
  • Use of personal protective equipment (PPE) may be required, including respirators, gloves, safety glasses, and protective clothing.

Physical Requirements
  • Work in various positions such as walking, standing, or sitting for prolonged durations, including reaching, bending, twisting, turning, and climbing.
  • Exposure to indoor factory conditions and outdoor environments with varying temperatures.
  • Ability to lift objects up to 25-35 pounds occasionally.
  • Frequent walking, standing, bending, and climbing stairs or ladders to access equipment and platforms

The salary range for this position is $100,000 to $150,000, with the final offer determined based on factors such as the candidate's experience, qualifications, skills, and education. In addition to a competitive base salary, this position is eligible to participate in Phlow's bonus and stock option programs. Phlow also offers a comprehensive benefits package that includes medical, life, and disability insurance; retirement savings plans; paid time off and company holidays; and education-related benefits. Many of these programs are fully funded or significantly subsidized by the company, reflecting our commitment to supporting the health, well-being, and professional development of our employees.

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