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TheAI Security Operations Engineeris responsible for securing, operationalizing, and scalingAI, Generative AI, and Agentic AI systemsacross the enterprise. This role bridgessecurity architecture, AI governance, and operational security, ensuring AI systems are designed, deployed, and monitored withsecuritybydesign and runtime assurance. This role operates as ahandson technical leaderand trusted advisor to engineering, AI, and business stakeholders, translating AI risk into actionable security controls without slowing innovation.

Key Responsibilities Leadsecurity design and operational oversightfor AI, Generative AI, and Agentic AI initiatives across the enterprise Define and operationalizeAI security frameworks, standards, and review processesthat govern model lifecycle, data usage, and autonomous behavior ConductAIfocused security architecture reviewsand threat modeling to identify and mitigate risks before deployment Support and monitoragentic and autonomous AI workflows, ensuring guardrails, accountability, and runtime visibility Partner with AI leadership and accelerator programs to enablesecure AI adoption at scale Translate complex AI and cybersecurity risks intoclear business and patientimpact narrativesfor senior leadership Contribute to and evolveenterprise AI governance programs, aligning with global regulatory expectations (e.g., NIST AI RMF, EU AI Act, privacy frameworks) Enable continuous improvement of AI security operations throughautomation, metrics, and repeatable processes Required Qualifications Bachelor's Degree 7+ years of experience incybersecurity architecture, security engineering, or security operations Demonstrated expertise securingcloud, hybrid, and onprem environments(AWS, Azure, GCP) Handson experience withAI/ML security, Generative AI, and Agentic AI concepts Proven ability to build and scaleenterprise security frameworksfor emerging technologies Strong background inthreat modeling, risk analysis, and secure solution design Experience advising and influencingmultiple stakeholders across hundreds of initiativesannually Ability to operate independently while shaping strategy and execution Preferred / Differentiating Skills Experience designing or contributing toenterprise AI cybersecurity frameworks Background supportingAI governance and accelerator programs Knowledge ofglobal regulatory and compliance requirements(NIST AI RMF, EU AI Act, GDPR, HIPAA, PCIDSS) Experience inlife sciences, healthcare, or highly regulated environments Certifications inAI governance or cybersecurity(e.g., AIGP, CISSP, CISM, CISA) What Success Looks Like AI initiatives move faster because security isembedded early, not reviewed late Agentic AI systems are deployed withclear guardrails, monitoring, and accountability Security reviews scale acrosshundreds of AI and nonAI projects annuallywithout becoming a bottleneck Leadership has clear visibility intoAI risk, posture, and readiness When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office

But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $136,044.00 - $204,066.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience

In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Are you ready to bring new insights and fresh thinking to the table. Fantastic.

We have one seat available, and we hope it's yours. Apply today. AstraZeneca embraces diversity and equality of opportunity.

We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.

We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. Date Posted 05-Jun-2026 Closing Date 19-Jun-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.

If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.