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Adme Dmpk Jobs (NOW HIRING)

Resolian

Scientist I ADME

Malvern, PA · On-site

$57K - $58K/yr

Design, execute, and interpret a range of in vitro ADME/DMPK studies, including: * Metabolic stability * Reaction phenotyping * Metabolite identification * CYP inhibition and induction * Transporter ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA

$130K - $150K/yr

Propose ADME/PK, biodistribution and PK-PD approaches at team discussions of high impact on project progression. * Manage consultants and vendors to support DMPK studies. * Partner with the discovery ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA · On-site

$130K - $150K/yr

Propose ADME/PK, biodistribution and PK-PD approaches at team discussions of high impact on project progression. * Manage consultants and vendors to support DMPK studies. * Partner with the discovery ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA · On-site

$130K - $150K/yr

Propose ADME/PK, biodistribution and PK-PD approaches at team discussions of high impact on project progression. * Manage consultants and vendors to support DMPK studies. * Partner with the discovery ...

Exelixis

DMPK Director

Alameda, CA

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

Exelixis

DMPK Director

Alameda, CA · On-site

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

Exelixis

DMPK Director

Alameda, CA · On-site

Lead the Translational IND- and NDA-enabling ADME work; characterize the ADME properties of molecules and collaborate to establish in vitro to in vivo correlations; ensure that all DMPK studies and ...

General Proximity

Head of DMPK

San Francisco, CA · On-site

What You'll Do In Vitro ADME * Provide strategic oversight of in vitro ADME activities including metabolic stability, CYP inhibition/induction, plasma protein binding, permeability (Caco-2/MDCK ...

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How much do adme dmpk jobs pay per year?

As of Jul 20, 2026, the average yearly pay for adme dmpk in the United States is $128,367.00, according to ZipRecruiter salary data. Most workers in this role earn between $58,000.00 and $188,500.00 per year, depending on experience, location, and employer.

What jobs can I do with clinical pharmacology?

With a background in clinical pharmacology, you can pursue roles such as clinical research scientist, pharmacovigilance specialist, regulatory affairs associate, or medical affairs professional. These positions often require knowledge of drug development, regulatory guidelines, and data analysis, and may involve working in pharmaceutical companies, research organizations, or healthcare settings.

What are ADME DMPK scientists?

ADME DMPK scientists specialize in understanding how drugs are Absorbed, Distributed, Metabolized, and Excreted (ADME) in the body, as well as evaluating Drug Metabolism and Pharmacokinetics (DMPK). Their role is crucial in drug discovery and development, as they design and perform experiments to predict a drug's behavior in humans, assess its safety, and optimize its efficacy. By analyzing how drugs interact with biological systems, they help researchers and pharmaceutical companies select the most promising drug candidates for further development.

What is ADME in drug development?

In drug development, ADME refers to Absorption, Distribution, Metabolism, and Excretion, which are key pharmacokinetic processes that determine how a drug behaves in the body. ADME studies help assess a drug's safety, efficacy, and optimal dosing, often involving laboratory experiments and modeling. Professionals in ADME DMPK roles analyze these processes to support drug candidate selection and development.

What are the key skills and qualifications needed to thrive as an ADME DMPK scientist, and why are they important?

To excel as an ADME DMPK scientist, you need a solid background in pharmacokinetics, drug metabolism, and analytical chemistry, typically supported by an advanced degree in a relevant scientific field. Expertise in bioanalytical tools such as LC-MS/MS, in vitro/in vivo assay development, and experience with data analysis software like WinNonlin are commonly required. Strong problem-solving abilities, attention to detail, and effective communication are valuable soft skills in this role. These competencies are essential for generating reliable data, informing drug development decisions, and collaborating within multidisciplinary project teams.

What is the DMPK department in pharma?

The DMPK (Drug Metabolism and Pharmacokinetics) department in pharma focuses on studying how drugs are absorbed, distributed, metabolized, and excreted in the body. Professionals in this department analyze drug behavior to optimize efficacy and safety, often using laboratory techniques and pharmacokinetic modeling. The role requires knowledge of biochemistry, pharmacology, and relevant regulatory guidelines.

What are some common challenges faced by professionals working in ADME DMPK roles, and how can they be addressed?

Professionals in ADME DMPK (Absorption, Distribution, Metabolism, Excretion, and Drug Metabolism and Pharmacokinetics) often encounter challenges such as interpreting complex biological data, keeping up with evolving regulatory requirements, and collaborating across multidisciplinary teams. Adapting quickly to new analytical technologies and effectively communicating findings to both scientists and non-scientists are also crucial. These challenges can be addressed by ongoing professional development, active participation in cross-functional meetings, and leveraging mentorship from experienced colleagues to stay current with best practices and regulatory expectations.

What does DMPK mean in pharma?

In the pharmaceutical industry, DMPK stands for Drug Metabolism and Pharmacokinetics, which involves studying how a drug is absorbed, distributed, metabolized, and excreted in the body. For an Adme Dmpk role, professionals typically analyze these processes to support drug development and optimize dosing strategies using laboratory and modeling tools.
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Infographic showing various Adme Dmpk job openings in the United States as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $128,367 per year, or $61.7 per hour.

Scientist I ADME

Resolian

Malvern, PA • On-site

$57K - $58K/yr

Other

Posted 16 days ago

Job description

Responsibilities

Scientific Responsibilities

  • Design, execute, and interpret a range of in vitro ADME/DMPK studies, including:
  • Metabolic stability
  • Reaction phenotyping
  • Metabolite identification
  • CYP inhibition and induction
  • Transporter studies
  • Plasma protein binding
  • Solubility and permeability assays
  • Analyze and interpret complex scientific datasets.
  • Prepare study reports, data summaries, and client presentations.
  • Troubleshoot technical challenges and recommend scientifically sound solutions.
  • Contribute to assay development, validation, and continuous improvement initiatives.
  • Ensure studies are conducted in accordance with client requirements and applicable quality standards.

Client and Project Responsibilities

  • Serve as a scientific point of contact for assigned client programs.
  • Participate in project kickoff meetings, study updates, and scientific discussions with clients.
  • Provide technical input during proposal development and study scoping activities.
  • Support Business Development teams by participating in scientific and capabilities presentations.
  • Build strong client relationships through scientific excellence and responsive communication.

Quality and Compliance

  • Maintain accurate laboratory records and documentation.
  • Ensure compliance with GLP, GCP, GMP, and internal quality systems as applicable.
  • Support client audits, regulatory inspections, and quality investigations.
  • Promote a culture of scientific integrity, quality, and continuous improvement.

Success Measures

  • Deliver high-quality, scientifically robust ADME data on time.
  • Build strong relationships with clients and internal stakeholders.
  • Contribute to repeat business through technical expertise and exceptional customer service.
  • Support growth of the ADME business through innovation, scientific leadership, and operational excellence.


Skills, Education & Qualifications

Required

  • M.S. with 3+ years of relevant industry experience; Pharmaceutical Sciences, Drug Metabolism, Biochemistry, Chemistry, or related field with 0-3 years of relevant experience; or
  • B.S. with 5+ years of relevant industry experience.
  • Experience conducting in vitro ADME or DMPK studies.
  • Experience within a Contract Research Organization (CRO) environment.
  • Strong understanding of drug metabolism, pharmacokinetics, and drug-drug interaction assessment.
  • Experience with LC-MS/MS data interpretation.
  • Excellent verbal and written communication skills.
  • Demonstrated ability to manage multiple projects simultaneously.

Preferred

  • Experience in metabolite identification (MetID).
  • Knowledge of regulatory guidance related to DMPK studies.
  • Experience supporting pharmaceutical and biotechnology clients.
  • Familiarity with software such as MassHunter, Analyst, Phoenix WinNonlin, MetabolitePilot, or equivalent.
  • Previous client-facing experience.
  • Experience contributing to business development activities or proposal generation.


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