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Adme Dmpk Jobs (NOW HIRING)

Evommune, Inc.

Director, DMPK

Palo Alto, CA · On-site

The Director, DMPK will serve as the DMPK program lead, responsible for establishing and executing ADME, PK, and PK-PD strategies that inform candidate selection, IND-enabling activities, and first ...

Relay Therapeutics

VP, Head of Drug Discovery

Cambridge, MA · On-site

$230K - $328K/yr

Deep understanding of medicinal chemistry, molecular design, ADME/DMPK, structure-based drug design, and computational chemistry. * Demonstrated success implementing modern computational approaches ...

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$45K

$128.4K

$232.5K

How much do adme dmpk jobs pay per year?

As of Aug 13, 2026, the average yearly pay for adme dmpk in the United States is $128,367.00, according to ZipRecruiter salary data. Most workers in this role earn between $58,000.00 and $188,500.00 per year, depending on experience, location, and employer.

What is an ADME DMPK scientist?

ADME DMPK scientists specialize in understanding how drugs are Absorbed, Distributed, Metabolized, and Excreted (ADME) in the body, as well as evaluating Drug Metabolism and Pharmacokinetics (DMPK). Their role is crucial in drug discovery and development, as they design and perform experiments to predict a drug's behavior in humans, assess its safety, and optimize its efficacy. By analyzing how drugs interact with biological systems, they help researchers and pharmaceutical companies select the most promising drug candidates for further development.

What are the key skills and qualifications needed to thrive as an ADME DMPK scientist?

To excel as an ADME DMPK scientist, you need a solid background in pharmacokinetics, drug metabolism, and analytical chemistry, typically supported by an advanced degree in a relevant scientific field. Expertise in bioanalytical tools such as LC-MS/MS, in vitro/in vivo assay development, and experience with data analysis software like WinNonlin are commonly required. Strong problem-solving abilities, attention to detail, and effective communication are valuable soft skills in this role. These competencies are essential for generating reliable data, informing drug development decisions, and collaborating within multidisciplinary project teams.

What are some common challenges faced by professionals working in ADME DMPK roles, and how can they be addressed?

Professionals in ADME DMPK (Absorption, Distribution, Metabolism, Excretion, and Drug Metabolism and Pharmacokinetics) often encounter challenges such as interpreting complex biological data, keeping up with evolving regulatory requirements, and collaborating across multidisciplinary teams. Adapting quickly to new analytical technologies and effectively communicating findings to both scientists and non-scientists are also crucial. These challenges can be addressed by ongoing professional development, active participation in cross-functional meetings, and leveraging mentorship from experienced colleagues to stay current with best practices and regulatory expectations.
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Adme Dmpk jobs near you
Infographic showing various Adme Dmpk job openings in the United States as of August 2026, with employment types broken down into 98% Full Time, and 2% Contract. Highlights an 87% Physical, 8% Hybrid, and 5% Remote job distribution, with an average salary of $128,367 per year, or $61.7 per hour.

Director, Clinical Pharmacology

Alkermes, Inc.

Waltham, MA • On-site

$130 - $180/hr

Other

Re-posted 8 days ago

Job description

We have an exciting opportunity for a highly motivated and experienced quantitative clinical pharmacologist to join our team supporting CNS therapeutic area as a key member of Clinical Pharmacology, DMPK and BA department. He/she will represent as a Clinical Pharmacology Lead and provide subject matter expertise on cross-functional project teams.

The Clinical Pharmacology Director provides strategic, scientific, and operational leadership for clinical pharmacology activities at the program level. This role serves as the primary clinical pharmacology representative on cross‑functional development teams and is accountable for dose selection and optimization across all stages of development. The Director will design and execute clinical pharmacology strategies by integrating PK/PD principles, quantitative modeling and simulation, translational sciences, and nonclinical ADME/DMPK data. Responsibilities include leading clinical pharmacology components of regulatory submissions, contributing to health authority interactions, and leading Clinical Pharmacology study design and execution.

This role is hybrid and requires the person to be onsite 3x a week in our Waltham, MA office.

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